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Familial central serous retinopathy

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Abstract

• Purpose: To study the familial occurrence of central serous retinopathy (CSR).

• Methods: We pooled data from eight eye clinics in Western Europe.

• Results: We collected 11 families that each had two to four members with CSR. In 10 families siblings and in one family a mother and son were affected. Sixty percent of the patients were male and 40% female. CSR was found in 55 (92%) of 60 eyes, 44 (80%) showing a chronic course. In 25 patients (83%) both eyes were affected. Most recent visual acuity was 0.5 or less in 17 (39%) and 0.2 or less in 8 (18%) of the eyes with chronic CSR.

• Conclusion: Our findings of familial occurrence and a chronic disorder that is progressive, diffuse, and bilateral suggest an inborn disposition to develop a clinically manifest disintegration of the retinal pigment epithelium in adulthood.

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Authors and Affiliations

  1. Afdeling Oogheelkunde, J3-T, Academisch Ziekenhuis, 2333 AA, Leiden, The Netherlands

    Jendo A. Oosterhuis

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  1. Jendo A. Oosterhuis
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Additional information

This study was performed with the collaboration of the following members of the European Fluorescein Angiography (FAN) Club: F. Bandello, Milan, Italy; R.A. Borsje, Leiden, The Netherlands; S.Y. Cohen, Créteil, France; A. Gaudric, Paris, France; F.G. Holz, London, UK; A. Leys, Louvain, Belgium; B.C.P. Polak, Rotterdam, The Netherlands; B. Snyers, Brussels, Belgium

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Oosterhuis, J.A. Familial central serous retinopathy. Graefe's Arch Clin Exp Ophthalmol 234, 337–341 (1996). https://doi.org/10.1007/BF00220710

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  • DOI: https://doi.org/10.1007/BF00220710

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