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01.12.2005 | Original

Outcome and changes over time in survival following severe burns from 1985 to 2004

verfasst von: Nele Brusselaers, Eric A. J. Hoste, Stan Monstrey, Kirsten E. Colpaert, Jan J. De Waele, Koenraad H. Vandewoude, Stijn I. Blot

Erschienen in: Intensive Care Medicine | Ausgabe 12/2005

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Abstract

Objective

To investigate outcome in severely burned patients over a 20-year period and to evaluate survival over time.

Design and setting

Historical cohort in a six-bed burn unit of a 1060-bed university hospital.

Patients

1385 patients admitted to the burn unit over a 20-year period.

Measurements and results

Outcome was evaluated in relation to the presence of three major risk factors for death: age 60 years or over, total burned surface area 40% or more, and the presence of inhalation injury. Overall mortality was 7.1%. When zero, one, two, or three risk factors were present, mortality was respectively 0.5%, 9.9%, 48.0%, and 90.5%. Over the study period the average proportional total burned surface area decreased as did mortality. The survival benefit was significant among patient groups with one or two risk factors present. Multivariate regression analysis adjusting for risk factors for death confirmed that survival improved over time (odds ratio 0.73 per 5-year period).

Conclusions

Global mortality following burns is low, and nearly all patients who die had at least one risk factor present. In the presence of three risk factors the prognosis following burns is particularly compromised. Taking into account that our patients over the past 20 years have been progressively less extensively burned and hence have a lesser at risk for death, survival following severe burns has continued to improve.

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Titel: Outcome and changes over time in survival following severe burns from 1985 to 2004
verfasst von: Nele Brusselaers
Eric A. J. Hoste
Stan Monstrey
Kirsten E. Colpaert
Jan J. De Waele
Koenraad H. Vandewoude
Stijn I. Blot
Publikationsdatum: 01.12.2005
Verlag: Springer-Verlag
Erschienen in: Intensive Care Medicine / Ausgabe 12/2005
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-005-2819-6

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Outcome and changes over time in survival following severe burns from 1985 to 2004