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Experimental Brain Research

Erschienen in:

01.01.2009 | Review

Plasticity in the adult brain: lessons from the visual system

verfasst von: Maria Spolidoro, Alessandro Sale, Nicoletta Berardi, Lamberto Maffei

Erschienen in: Experimental Brain Research | Ausgabe 3/2009

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Abstract

While cortical circuits display maximal sensitivity to sensory experience during critical periods of early postnatal development, far less plasticity is present in the mature brain. Ocular dominance shift of visual cortical neurons in response to eye occlusion and recovery of visual functions from a period of sensory deprivation are two classical models in the study of critical period determinants in the visual cortex. Recent papers employing various pharmacological and environmental strategies have shown that it is possible to reinstate much greater levels of plasticity in the adult visual cortex than previously suspected. These studies point toward intracortical inhibition as a crucial determinant for critical period regulation in the visual system and have a great potential for therapeutic rehabilitation and recovery from injury in the adult brain.

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Titel: Plasticity in the adult brain: lessons from the visual system
verfasst von: Maria Spolidoro
Alessandro Sale
Nicoletta Berardi
Lamberto Maffei
Publikationsdatum: 01.01.2009
Verlag: Springer-Verlag
Erschienen in: Experimental Brain Research / Ausgabe 3/2009
Print ISSN: 0014-4819
Elektronische ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-008-1509-3

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