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Two-Dimensional Echocardiographic Valve Measurements in Healthy Children: Gender-Specific Differences

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An Erratum to this article was published on 06 December 2007

Abstract

The goal of this study was to create nomograms of echocardiographic two-dimensional valve dimensions based on a large group of children without heart disease. Children aged 0–18 years underwent standard echocardiographic evaluation. Referring diagnoses were chest pain, heart murmur, or syncope. Only patients with a structurally normal heart and normal systolic and diastolic function were included. All four valves were measured at their maximal dimensions. A total of 748 children (314 girls and 434 boys) met the inclusion criteria. Mean values and standard deviations were calculated, and z value nomograms based on body surface area were developed. Surprisingly, the boys had larger valve dimensions at all ages. These valve dimension differences were statistically significant for three of four valves even after adjustment for the differences in body sizes. The difference may be due to higher circulating blood volume in boys compared to that in girls. Because the differences are subtle, they reach statistical significance only when evaluated in a large group of subjects. Presented normal value data will be helpful in following cardiology patients and evaluating intervention strategy in patients with valve hypoplasia.

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References

  1. T Akiba M Yoshikawa S Otaki et al. (1986) ArticleTitleEchocardiographic measurements of left ventricle in normal infants and children Tohoki J Exp Med 149 31–37 Occurrence Handle1:STN:280:DyaL283ptVertA%3D%3D

    CAS  Google Scholar 

  2. GL Burke RA Arcilla WS Culpepper et al. (1987) ArticleTitleBlood pressure and echocardiographic measures in children: the Bogalusa Heart Study Circulation 75 106–114 Occurrence Handle2947739 Occurrence Handle1:STN:280:DyaL2s%2FnvVOntg%3D%3D

    PubMed  CAS  Google Scholar 

  3. PEF Daubeney EH Blackstone RG et al. Weintraub (1999) ArticleTitleRelationship of the dimension of cardiac structures to body size: an echocardiographic study in normal infants and children Cardiol Young 9 402–410 Occurrence Handle10476831 Occurrence Handle1:STN:280:DyaK1MvgsVCrsw%3D%3D Occurrence Handle10.1017/S1047951100005217

    Article  PubMed  CAS  Google Scholar 

  4. G Simone Particlede RB Devereux SR Daniels RA Meyer (1995) ArticleTitleGender differences in left ventricular growth Hypertension 26 979–983 Occurrence Handle7490158

    PubMed  Google Scholar 

  5. A Evangelista HG Casillo Particledel T Gonsales-Alujas et al. (1996) ArticleTitleNormal values of valvular annular areas. Comparison of the results of a necroscopy and an echocardiographic series Rev Espaniola de Cardiol 49 111–116 Occurrence Handle1:STN:280:DyaK2s7gsF2ksA%3D%3D

    CAS  Google Scholar 

  6. HP Gutgesell JT Bricker EV Colvin LA Latson EP Hawkins (1984) ArticleTitleAtrioventricular valve annular diameter: two-dimensional echocardiographic–autopsy correlation Am J Cardiol 53 1652–1655 Occurrence Handle6731311 Occurrence Handle10.1016/0002-9149(84)90596-4 Occurrence Handle1:STN:280:DyaL2c3ivVantw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  7. DA Halon N Amitai MS Gotsman BS Lewis (1979) ArticleTitleSerial echocardiography during the first 3 month of life in normal neonates Eur J Cardiol 9 393–404 Occurrence Handle456397 Occurrence Handle1:STN:280:DyaE1M3htlCrtw%3D%3D

    PubMed  CAS  Google Scholar 

  8. WL Henry J Ware JM Gardin et al. (1978) ArticleTitleEchocardiographic measurements in normal subjects Circulation 57 278–285 Occurrence Handle618615 Occurrence Handle1:STN:280:DyaE1c%2Fmt12mtw%3D%3D

    PubMed  CAS  Google Scholar 

  9. DH King EO Smith JC Huhta HP Gutgesell (1985) ArticleTitleMitral and tricuspid valve annular diameter in normal children determined by two-dimensional echocardiography Am J Cardiol 55 787–789 Occurrence Handle3976526 Occurrence Handle1:STN:280:DyaL2M7ksFGltg%3D%3D

    PubMed  CAS  Google Scholar 

  10. SM Nidorf MH Picard MO Triulzi et al. (1992) ArticleTitleNew perspectives in the assessment of cardiac chamber dimensions during development and adulthood J Am Coll Cardiol 19 983–988 Occurrence Handle1552123 Occurrence Handle1:STN:280:DyaK383gt1Gqsg%3D%3D Occurrence Handle10.1016/0735-1097(92)90282-R

    Article  PubMed  CAS  Google Scholar 

  11. PW O'Leary K Durongpisitkul T Cordes et al. (1998) ArticleTitleDiastolic ventricular function in children: a Doppler echocardiographic study establishing normal values and predictors of increased ventricular end-diastolic pressure Mayo Clinic Proc 73 616–628 Occurrence Handle10.4065/73.7.616

    Article  Google Scholar 

  12. HJA Rimoldi M Lev (1963) ArticleTitleA note on the concept of normality and abnormality in quantification of pathologic findings in congenital heart disease Pediatr Clin North Am 10 589–591

    Google Scholar 

  13. CLL Roge NH Silverman PA Hart RM Ray (1978) ArticleTitleCardiac structure growth pattern determined by echocardiography Circulation 57 285–290 Occurrence Handle618616 Occurrence Handle1:STN:280:DyaE1c%2Fmt12mtA%3D%3D

    PubMed  CAS  Google Scholar 

  14. MJ Roman RB Devereux R Kramer-Fox J O'Loughlin (1989) ArticleTitleTwo-dimensional echocardiographic aortic root dimensions in normal children and adults Am J Cardiol 64 507–512 Occurrence Handle2773795 Occurrence Handle1:STN:280:DyaL1MzntFGjtg%3D%3D

    PubMed  CAS  Google Scholar 

  15. DJ Sahn A DeMaria J Kisslo A Weyman (1978) ArticleTitleRecommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements Circulation 58 1072–1083 Occurrence Handle709763 Occurrence Handle1:STN:280:DyaE1M%2Fktl2msw%3D%3D

    PubMed  CAS  Google Scholar 

  16. ML Sheil O Jenkins G Sholler (1995) ArticleTitleEchocardiographic assessment of aortic root dimensions in normal children based on measurements of a new ratio of aortic size independent of growth Am J Cardiol 75 711–715 Occurrence Handle7900666 Occurrence Handle10.1016/S0002-9149(99)80659-6 Occurrence Handle1:STN:280:DyaK2M3gvVKjtQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  17. AR Snider MA Enderlein DF Teitel RP Juster (1984) ArticleTitleTwo-dimensional echocardiographic determination of aortic and pulmonary artery sizes from infancy to adulthood in normal subjects Am J Cardiol 53 218–224 Occurrence Handle6691264 Occurrence Handle10.1016/0002-9149(84)90715-X Occurrence Handle1:STN:280:DyaL2c7gtFaqtw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  18. R Solinger F Elbl K Minhas (1973) ArticleTitleEchocardiography in the normal neonate Circulation 47 108–118 Occurrence Handle4686588 Occurrence Handle1:STN:280:DyaE3s%2FpsFKmsw%3D%3D

    PubMed  CAS  Google Scholar 

  19. TA Tacy RP Vermilion A Ludomirsky (1995) ArticleTitleRange of normal valve annulus size in neonates Am J Cardiol 75 541–543 Occurrence Handle7864012 Occurrence Handle10.1016/S0002-9149(99)80605-5 Occurrence Handle1:STN:280:DyaK2M7mvVajtQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

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Acknowledgment

We thankWendi Long for her help in conducting the study.

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Author notes

  1. M. V. Zilberman

    Present address: Division of Cardiology, Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI, 48201, USA

Authors and Affiliations

  1. Division of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA

    M. V. Zilberman, P. R. Khoury & R. T. Kimball

Authors
  1. M. V. Zilberman
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  2. P. R. Khoury
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  3. R. T. Kimball
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Corresponding author

Correspondence to M. V. Zilberman.

Additional information

An erratum to this article is available at http://dx.doi.org/10.1007/s00246-007-9164-1.

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Zilberman, M.V., Khoury, P.R. & Kimball, R.T. Two-Dimensional Echocardiographic Valve Measurements in Healthy Children: Gender-Specific Differences . Pediatr Cardiol 26, 356–360 (2005). https://doi.org/10.1007/s00246-004-0736-z

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