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01.11.2014 | Special Annual Issue

Surgery for focal cortical dysplasia in children using intraoperative mapping

verfasst von: Vera C. Terra, Ursula Thomé, Sara S. Rosset, Sandra S. Funayama, Antonio Carlos dos Santos, Marcelo Volpon dos Santos, Américo C. Sakamoto, Helio R. Machado

Erschienen in: Child's Nervous System | Ausgabe 11/2014

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Abstract

Objective

Children with malformation of cortical development represent a significant proportion of pediatric epilepsy surgery candidates. Here, we describe a single-center experience with pediatric patients who underwent surgery for intractable epilepsy due to focal cortical dysplasia (FCD).

Methods

Clinical data of 78 patients under 18 years of age with diagnosis of intractable epilepsy due to FCD who underwent surgery from January 1996 to January 2012 were reviewed comparing data of patients submitted to electrocorticography (ECoG) with those without ECoG.

Results

Patients’ mean age at surgery was 8.52 ± 4.99 years; mean age at epilepsy onset was 2.55 ± 3.01 years. Almost 80 % of the patients underwent ECoG register that was essential for delimitation of surgical resection in 66 out of 78 patients. ECoG was performed in all patients with extratemporal lesions, and the most common FCD found was type II. Seizure outcome was similar in groups with or without ECoG.

Conclusions

Tailored resection of FCD lesions for intractable epilepsy can be safely performed in children with a good seizure outcome and low complication rate. Epilepsy surgery should be considered for all patients with FCD and refractory epilepsy.

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Titel: Surgery for focal cortical dysplasia in children using intraoperative mapping
verfasst von: Vera C. Terra
Ursula Thomé
Sara S. Rosset
Sandra S. Funayama
Antonio Carlos dos Santos
Marcelo Volpon dos Santos
Américo C. Sakamoto
Helio R. Machado
Publikationsdatum: 01.11.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Child's Nervous System / Ausgabe 11/2014
Print ISSN: 0256-7040
Elektronische ISSN: 1433-0350
DOI: https://doi.org/10.1007/s00381-014-2459-7

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Surgery for focal cortical dysplasia in children using intraoperative mapping