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Journal of Neurology

Erschienen in:

01.07.2013 | Review

Imaging resting state brain function in multiple sclerosis

verfasst von: Massimo Filippi, Federica Agosta, Edoardo G. Spinelli, Maria Assunta Rocca

Erschienen in: Journal of Neurology | Ausgabe 7/2013

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Abstract

In multiple sclerosis (MS), physical and cognitive deficits not only reflect structural damage, but also functional imbalance in and between brain networks. Resting-state functional magnetic resonance imaging (fMRI) allows one to investigate intrinsic, synchronized brain activity across the whole brain, and to measure the degree of functional correlation between different cortical regions. This review describes the major findings obtained in MS patients at different clinical stages using resting state fMRI, and discusses how the use of fMRI techniques may improve our ability to identify novel biomarkers useful in the context of the diagnostic work-up, establishing prognosis and monitoring treatment.

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Titel: Imaging resting state brain function in multiple sclerosis
verfasst von: Massimo Filippi
Federica Agosta
Edoardo G. Spinelli
Maria Assunta Rocca
Publikationsdatum: 01.07.2013
Verlag: Springer Berlin Heidelberg
Erschienen in: Journal of Neurology / Ausgabe 7/2013
Print ISSN: 0340-5354
Elektronische ISSN: 1432-1459
DOI: https://doi.org/10.1007/s00415-012-6695-z

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