Erschienen in:
01.10.2011 | Original Article
Invasive Rhino-Orbital Aspergillosis
verfasst von:
Vipin Arora, Nitin M. Nagarkar, Arjun Dass, Arvind Malhotra
Erschienen in:
Indian Journal of Otolaryngology and Head & Neck Surgery
|
Ausgabe 4/2011
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Abstract
Invasive aspergillosis usually affects immune-compromised patients and is common in diabetics. Proptosis, visual loss and ophthalmoplegia due to intra-orbital extension are common presentations. Three out of five patients in our series were immune-compromised. All the patients had visual loss and three patients presented with unilateral blindness. Three patients were treated by surgical debridement followed by Amphotericin B therapy. Two patients who had intra-cranial extension of the disease died during the treatment. Only one patient had improvement in vision following the treatment. High index of suspicion in immune-compromised patients, early diagnosis and prompt aggressive treatment is required to achieve clinical cure.