nach oben

Erschienen in:

01.12.2007 | Positionspapier

Prophylaxe der infektiösen Endokarditis

verfasst von: Christoph K. Naber, Bilal Al-Nawas, Helmut Baumgartner, Hans-Jürgen Becker, Michael Block, Raimund Erbel, Georg Ertl, Ursula Flückiger, Damian Franzen, Christa Gohlke-Bärwolf, Rainer Gattringer, Wolfgang Graninger, Werner Handrick, Matthias Herrmann, Matthias Herrmann, Ruth Heying, Dieter Horstkotte, Andres Jaussi, Peter Kern, Hans-Heiner Kramer, Sebastian Kühl, Philipp M. Lepper, Rainer G. Leyh, Hartmut Lode, Uwe Mehlhorn, Philippe Moreillon, Andreas Mügge, Reinier Mutters, Jörg Niebel, Georg Peters, Raphael Rosenhek, Achim A. Schmaltz, Harald Seifert, Pramod M. Shah, Helmut Sitter, Wilfried Wagner, Karl Werdan, Michel Zuber

Erschienen in: Die Kardiologie | Ausgabe 4/2007

Einloggen, um Zugang zu erhalten

Auszug

Bearbeitet im Auftrag der Kommission für Klinische Kardiologie: …

Diese Empfehlung unterscheidet sich von den Empfehlungen der American Heart Association.

Wilson W, Taubert KA, Gewitz M et al. (2007) Prevention of infective endocarditis. Guidelines from the American Heart Association. A Guideline from the American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. Circulation 116: 1736–1754CrossRefPubMed

Lorenz W, Ollenschläger G, Geradts M et al. (2001) Das Leitlinien-Manual. Entwicklung und Implementierung von Leitlinien in der Medizin. Z Ärztl Fortbildung Qualitätssicherung 95/1. Auflage

The AGREE-Collaboration (2003) Appraisal of Guidelines for Research and Evaluation (AGREE) Instrument. http://www.agreecollaboration.org

Osterspey A (2006) Erstellung von Leitlinien in der Deutschen Gesellschaft fur Kardiologie – Herz- und Kreislaufforschung e.V. Clin Res Cardiol 95: 692–695CrossRefPubMed

Osler W (1885) Gulstonian lectures on malignant endocarditis. lecture I, and lecture II. Lancet 1: 415–418, 459–464.CrossRef

Okell CC, Elliott SD (1935) Bacteraemia and oral sepsis: with special reference to the aetiology of subacute endocarditis. Lancet 2: 869–872CrossRef

Danchin N, Duval X, Leport C (2005) Prophylaxis of infective endocarditis: French recommendations 2002. Heart ;91: 715–718

Gould FK, Elliott TS, Foweraker J et al. (2006) Guidelines for the prevention of endocarditis: report of the Working Party of the British Society for Antimicrobial Chemotherapy. J Antimicrob Chemother 57: 1035–1042CrossRefPubMed

Durack DT, Beeson PB (1972) Experimental bacterial endocarditis, II: survival of a bacteria in endocardial vegetations. Br J Exp Pathol 53: 50–53PubMed

10.

Lockhart PB, Durack DT (1999) Oral microflora as cause of endocarditis and other distant site infections. Infect Dis Clin North Am 13: 833–850CrossRefPubMed

11.

Roberts GJ, Holzel HS, Sury MR et al. (1997) Dental bacteremia in children. Pediatr Cardiol. 18: 24–27

12.

Pallasch TJ, Slots J (1996) Antibiotic prophylaxis and the medically compromised patient. Periodontol 2000 10: 107–138CrossRefPubMed

13.

Lockhart PB (2000) The risk for endocarditis in dental practice. Periodontol 2000 23: 127–135CrossRefPubMed

14.

Cobe HM (1954) Transitory bacteremia. Oral Surg Oral Med Oral Pathol 7: 609–615CrossRefPubMed

15.

Sconyers JR, Crawford JJ, Moriarty JD (1973) Relationship of bacteremia to toothbrushing in patients with periodontitis. Am Dent Assoc 87: 616–622.

16.

Forner L, Larsen T, Kilian M, Holmstrup P (2006) Incidence of bacteremia after chewing, tooth brushing and scaling in individuals with periodontal inflammation. Clin Periodontol 33: 401–407CrossRef

17.

Rise E, Smith JF, Bell J (1969) Reduction of bacteremia after oral manipulations. Arch Otolaryngol 90: 198–201PubMed

18.

Schlein RA, Kudlick EM, Reindorf CA et al. (1991) Tooth-brushing and transient bacteremia in patients undergoing orthodontic treatment. Am Orthod Dentofacial Orthop 99: 466–472CrossRef

19.

Faden HS (1974) Letter: Dental procedures and bacteremia. Ann Intern Med 81: 274PubMed

20.

Round H, Kirkpatrick HJR, Hails CG (1936) Further investigations on bacteriological infections of the mouth. Proc Soc Med 29: 1552–1556

21.

Felix JE, Rosen S, App GR (1971) Detection of bacteremia after the use of an oral irrigation device in subjects with periodontitis. Periodontol 42: 785–787

22.

O’Leary TJ, Shafer WG, Swenson HM et al. (1970) Possible penetration of crevicular tissue from oral hygiene procedures, I: use of oral irrigating devices. Periodontol 41: 158–162

23.

Rahn R (1989) Bakteriämien bei zahnärztlich-chirurgischen Eingriffen. Carl Hanser, München

24.

Rahn R, Shah PM, Schaefer V et al. (1986) Bakteriämie nach Zahnentfernung – Einfluss verschiedener Faktoren. ZWR 95: 822–826PubMed

25.

Rahn R, Shah PM, Schaefer V et al. (1986) Bakteriämie nach Zahnentfernung – Einfluss von Art und Dauer des Eingriffes. ZWR 1986: 1056–1063

26.

Rahn R, Shah PM, Schaefer V et al. (1987) Bakteriämie nach chirurgisch-endodontischen Eingriffen. ZWR 96: 903–907PubMed

27.

Rahn R, Shah PM, Schaefer V et al. (1987) Bestimmung der Keimzahl und Kinetik der Keimeliminierung bei Bakteriämie nach Zahnentfernung. Dtsch Zahnärztl Z 42: 964–969PubMed

28.

Rahn R, Shah PM, Schäfer V et al. (1988) Orale Endokarditis-Prophylaxe bei zahnärztlich-chirurgischen Eingriffen. Schweiz Monatsschr Zahnmed 98: 478–481PubMed

29.

Rahn R, Shah PM, Schaefer V, Grabbert U (1990) Endokarditis-Risiko bei Anwendung von Mundduschen. ZWR 99: 266–270PubMed

30.

Shah PM, Schaefer V, Finke HJ, Rahn R (1989) Vergleich zweier Blutkultursysteme durch Nachweis von Bakteriämien nach Zahnextraktion. Lab Med 13: 209–212

31.

Fowler VG, Scheld WM, Bayer AS (2005) Endocarditis and intravascular infections. In: Mandell GL, Bennett JE, Dolin R (eds) Principles and practices of infectious diseases. Elsevier Churchill Livingstone, Philadelphia, Pa, pp 975–1021

32.

Roberts GJ, Jaffray EC, Spratt DA et al. (2006) Duration, prevalence and intensity of bacteraemia after dental extractions in children. Heart 92: 1274–1277CrossRefPubMed

33.

Lucas VS, Lytra V, Hassan T et al. (2002) Comparison of lysis filtration and an automated blood culture system (BACTEC) for detection, quantification, and identification of odontogenic bacteremia in children. J Clin Microbiol 40: 3416–3420CrossRefPubMed

34.

Benetka O, Block M, Sangha O et al. (1999) On behalf of the ALKK, Arbeitsgemeinschaft Leitender Kardiologischer Krankenhausärzte. Clinical course of infective endocarditis in the late nineties: preliminary results of the ALKK endocarditis registry

35.

van der Meer JT, Thompson J, Valkenburg HA, Michel MF (1992) Epidemiology of bacterial endocarditis in The Netherlands, II: antecedent procedures and use of prophylaxis. Arch Intern Med 152: 1869–1873CrossRef

36.

Hirsh HL, Vivino JJ, Merril A, Dowling HF (1948) Effect of prophylactically administered penicillin on incidence of bacteremia following extraction of teeth. Arch Intern Med 81: 868–878

37.

Lockhart PB, Brennan MT, Kent ML et al. (2004) Impact of amoxicillin prophylaxis on the incidence, nature, and duration of bacteremia in children after intubation and dental procedures. Circulation 109: 2878–2884CrossRefPubMed

38.

Shanson DC, Akash S, Harris M, Tadayon M (1985) Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance. J Antimicrob Chemother 15: 83–90CrossRefPubMed

39.

Rahn R, Shah PM, Schäfer V et al. (1987) Endokarditis Prophylaxe bei zahnärztlich-chirurgischen Eingriffen. ZWR 5: 438–440

40.

Roberts GJ, Radford P, Holt R (1987) Prophylaxis of dental bacteraemia with oral amoxycillin in children. Br Dent J 162: 179–182CrossRefPubMed

41.

Hall G, Hedstrom SA, Heimdahl A, Nord CE (1993) Prophylactic administration of penicillins for endocarditis does not reduce the incidence of postextraction bacteremia. Clin Infect Dis 17: 188–194PubMed

42.

Hall G, Heimdahl A, Nord CE (1995) Effects of prophylactic administration of cefaclor on transitorisch bacteremia after dental extraction. Eur J Clin Microbiol Infect Dis 15: 646–649CrossRef

43.

Hall G, Heimdahl A, Nord CE (1999) Bacteremia after oral surgery and antibiotic prophylaxis for endocarditis. Clin Infect Dis 29: 1–8CrossRefPubMed

44.

Eldirini AH (1968) Effectiveness of epinephrine in local anesthetic solutions on the bacteremia following dental extraction. J Oral Ther Pharmacol 4: 317–326PubMed

45.

Lockhart PB (1996) An analysis of bacteremias during dental extractions: a double-blind, placebo-controlled study of chlorhexidine. Arch Intern Med 156: 513–520CrossRefPubMed

46.

Rahn R, Schneider S, Diehl O et al. (1995) Preventing post-treatment bacteremia: comparing topical povidone-iodine and chlorhexidine. J Am Dent Assoc 126: 1145–1149PubMed

47.

Oliver R, Roberts GJ, Hooper L (2004) Penicillins for the prophylaxis of bacterial endocarditis in dentistry. Cochrane Database Syst Rev 2004: CD003813.

48.

Horstkotte D, Rosin H, Friedrichs W, Loogen F (1987) Contribution for choosing the optimal prophylaxis of bacterial endocarditis. Eur Heart J 8 (Suppl J): 379–381

49.

Imperiale TF, Horwitz RI (1990) Does prophylaxis prevent postdental infective endocarditis? A controlled evaluation of protective efficacy. Am J Med 88: 131–136CrossRefPubMed

50.

Van der Meer JT, Van Wijk W, Thompson J et al. (1992) Efficacy of antibiotic prophylaxis for prevention of native-valve endocarditis. Lancet 339: 135–139CrossRef

51.

van der Meer JT, van Wijk W, Thompson J et al. (1992) Awareness of need and actual use of prophylaxis: lack of patient compliance in the prevention of bacterial endocarditis. J Antimicrob Chemother 29: 187–194CrossRef

52.

Duval X, Alla F, Hoen B et al. (2006) Estimated risk of endocarditis in adults with predisposing cardiac conditions undergoing dental procedures with or without antibiotic prophylaxis. Clin Infect Dis 42: e102–e107CrossRefPubMed

53.

Strom BL, Abrutyn E, Berlin JA et al. (1998) Dental and cardiac risk factors for infective endocarditis: a population-based, case-control study. Ann Intern Med 129: 761–769PubMed

54.

Tleyjeh IM, Steckelberg JM, Murad HS et al. (2005) Temporal trends in infective endocarditis: a population-based study in Olmsted County, Minnesota. JAMA 293: 3022–3028CrossRefPubMed

55.

Griffin MR, Wilson WR, Edwards WD et al. (1985) Infective endocarditis: Olmsted County, Minnesota, 1950 through 1981. JAMA 254: 1199–1202CrossRefPubMed

56.

Delahaye F, Goulet V, Lacassin F et al. (1995) Characteristics of infective endocarditis in France in 1991: a 1-year survey. Eur Heart J 16: 394–401PubMed

57.

Hoen B, Alla F, Selton-Suty C et al. (2002) Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA 288: 75–81CrossRefPubMed

58.

Steckelberg JM, Wilson WR (1993) Risk factors for infective endocarditis. Infect Dis Clin North Am 7: 9–19PubMed

59.

Gersony WM, Hayes CJ, Driscoll DJ et al. (1993) Bacterial endocarditis in patients with aortic stenosis, pulmonary stenosis, or ventricular septal defect. Circulation 87 [Suppl]: I-121–I-126

60.

Starkebaum M, Durack D, Beeson P (1977) The „incubation period“ of subacute bacterial endocarditis. Yale J Biol Med 50: 49–58PubMed

61.

Pallasch TJ, Wahl MJ (2003) Focal infection: new age or ancient history? Endodontic Topics 4: 32–45CrossRef

62.

Pallasch TJ (2003) Antibiotic prophylaxis: problems in paradise. Dent Clin North Am 47: 665–679CrossRefPubMed

63.

Gould IM, Buckingham JK (1993) Cost effectiveness of prophylaxis in dental practice to prevent infective endocarditis. Br Heart J 70: 79–83CrossRefPubMed

64.

Devereux RB, Frary CJ, Kramer-Fox R et al. (1994) Cost-effectiveness of infective endocarditis prophylaxis for mitral valve prolapse with or without a mitral regurgitant murmur. Am J Cardiol 74: 1024–1029CrossRefPubMed

65.

Caviness AC, Cantor SB, Allen CH, Ward MA (2004) A cost-effectiveness analysis of bacterial endocarditis prophylaxis for febrile children who have cardiac lesions and undergo urinary catheterization in the emergency department. Pediatrics 113: 1291–1296CrossRefPubMed

66.

Agha Z, Lofgren RP, Van Ruiswyk JV (2005) Is antibiotic prophylaxis for bacterial endocarditis cost-effective? Med Decis Making 25: 308–320CrossRefPubMed

67.

Jones TD, Baumgartner L, Bellows MT et al. (1955) Prevention of rheumatic fever and bacterial endocarditis through control of streptococcal infections. Circulation 11: 317–320

68.

Horstkotte D, Follath F, Gutschik E et al. (2004) Guidelines on prevention, diagnosis and treatment of infective endocarditis executive summary; the task force on infective endocarditis of the European society of cardiology. Eur Heart J 25: 267–276CrossRefPubMed

69.

Wilson WR, Jaumin PM, Danielson GK et al. (1974) Prosthetic valve endocarditis. Ann Intern Med 82: 751–756

70.

Wilson WR, Danielson GK, Giuliani ER, Geraci JE (1982) Prosthetic valve endocarditis. Mayo Clin Proc 57: 155–161PubMed

71.

Wilson WR, Geraci JE, Wilkowske CJ, Washington JA II (1978) Short-term intramuscular therapy with procaine penicillin plus streptomycin for infective endocarditis due to viridans streptococci. Circulation 57:1158–1161PubMed

72.

Anderson DJ, Olaison L, McDonald JR et al. (2005) Enterococcal prosthetic valve infective endocarditis: report of 45 episodes from the International Collaboration on Endocarditis-merged database. Eur J Clin Microbiol Infect Dis 24: 665–670CrossRefPubMed

73.

Chu VH, Cabell CH, Abrutyn E et al. (2004) Native valve endocarditis due to coagulase negative staphylococci: report of 99 episodes from the International Collaboration on Endocarditis Merged Database. Clin Infect Dis 39: 1527–1530CrossRefPubMed

74.

Lalani T, Kanafani ZA, Chu VH et al. (2006) Prosthetic valve endocarditis due to coagulase negative staphylococci: findings from the International Collaboration on Endocarditis Merged Database. Eur J Clin Microbiol Infect Dis 25: 365–368CrossRefPubMed

75.

McDonald JR, Olaison L, Anderson DJ et al. (2005) Enterococcal endocarditis: 107 cases from the International Collaboration on Endocarditis Merged Database. Am J Med 118: 759–766.CrossRefPubMed

76.

Sexton DJ, Tenenbaum MJ, Wilson WR et al. (1998) Ceftriaxone once daily for four weeks compared with ceftriaxone plus gentamicin once daily for two weeks for treatment of endocarditis due to penicillin-susceptible streptococci. Clin Infect Dis 27: 1470–1474CrossRefPubMed

77.

Francioli P, Etienne J, Hoigne R et al. (1992) Treatment of streptococcal endocarditis with a single daily dose of ceftriaxone sodium for 4 weeks: efficacy and outpatient treatment feasibility. JAMA 267: 264–267CrossRefPubMed

78.

Wilson WR, Wilkowske CJ, Wright AJ et al. (1984) Treatment of streptomycin-susceptible and streptomycin-resistant enterococcal endocarditis. Ann Intern Med 100: 816–823PubMed

79.

Mansur AJ, Dal Bo CM, Fukushima JT et al. (2001) Relapses, recurrences, valve replacements, and mortality during the long-term follow-up after infective endocarditis. Am Heart J 141: 78–86CrossRefPubMed

80.

Baddour LM (1988) Twelve-year review of recurrent native-valve infective endocarditis: a disease of the modern antibiotic era. Rev Infect Dis 10: 1163–1170PubMed

81.

Chu VH, Sexton DJ, Cabell CH et al. (2005) Repeat infective endocarditis: differentiating relapse from reinfection. Clin Infect Dis 41: 406–409CrossRefPubMed

82.

Welton DE, Young JB, Gentry WO et al. (1979) Recurrent infective endocarditis: analysis of predisposing factors and clinical features. Am J Med 66: 932–938CrossRefPubMed

83.

Levison ME, Kaye D, Mandell GL, Hook EW (1970) Characteristics of patients with multiple episodes of bacterial endocarditis. JAMA 211: 1355–1357CrossRefPubMed

84.

Renzulli A, Carozza A, Romano G et al. (2001) Recurrent infective endocarditis: a multivariate analysis of 21 years of experience. Ann Thorac Surg 72: 39–43CrossRefPubMed

85.

Erbel R, Liu F, Ge J, Kupferwasser I (1995) Identification of high-risk subgroups in infective endocarditis and the role of echocardiography. Eur Heart J 16: 588–602PubMed

86.

Kaplan EL, Rich H, Gersony W, Manning J (1979) A collaborative study of infective endocarditis in the 1970s: emphasis on infections in patients who have undergone cardiovascular surgery. Circulation 59: 327–335PubMed

87.

Coward K, Tucker N, Darville T (2003) Infective endocarditis in Arkansan children from 1990 through 2002. Pediatr Infect Dis J 22: 1048–1052CrossRefPubMed

88.

Saiman L, Prince A, Gersony WM (1993) Pediatric infective endocarditis in the modern era. J Pediatr 122: 847–853CrossRefPubMed

89.

Dodo H, Child JS (1996) Infective endocarditis in congenital heart disease. Cardiol Clin 14: 383–392CrossRefPubMed

90.

Martin JM, Neches WH, Wald ER (1997) Infective endocarditis: 35 years of experience at a children’s hospital. Clin Infect Dis 24: 669–675PubMed

91.

Parras F, Bouza E, Romero J et al. (1990) Infectious endocarditis in children. Pediatr Cardiol 11: 77–81CrossRefPubMed

92.

Takeda S, Nakanishi T, Nakazawa M (2005) A 28-year trend of infective endocarditis associated with congenital heart diseases: a single institute experience. Pediatr Int 47: 392–396CrossRefPubMed

93.

Sherman-Weber S, Axelrod P, Suh B et al. (2004) Infective endocarditis following orthotopic heart transplantation: 10 cases and a review of the literature. Transpl Infect Dis 6: 165–170CrossRefPubMed

94.

Conner HD, Haberman S, Collings CK, Winford TE (1967) Bacteremias following periodontal scaling in patients with healthy appearing gingiva. J Periodontol 38: 466–472PubMed

95.

McEntegart MG, Porterfield JS (1949) Bacteraemia following dental extractions. Lancet 2: 596–598CrossRefPubMed

96.

Robinson L, Kraus FW, Lazansky JP et al. (1950) Bacteremias of dental origin, II: a study of the factors influencing occurrence and detection. Oral Surg Oral Med Oral Pathol 3: 923–936CrossRef

97.

Roberts GJ (1999) Dentists are innocent! „Everyday“ bacteremia is the real culprit: a review and assessment of the evidence that dental surgical procedures are a principal cause of bacterial endocarditis in children. Pediatr Cardiol 20: 317–325CrossRefPubMed

98.

Hockett RN, Loesche WJ, Sodeman TM (1977) Bacteraemia in asymptomatic human subjects. Arch Oral Biol 22: 91–98CrossRefPubMed

99.

Rahn R, Frenkel G, Atamni F et al. (1986) Bakteriämie bei intraligamentärer Anästhesie. Zahnärztl Mitteilungen 76: 2121–2129

100.

Rahn R, Frenkel G, Atamni F et al. (1987) Bakteriämie nach Intradesmodontaler Anästhesie. Schweiz Monatsschr Zahnmed 97: 859–863PubMed

101.

Rahn R, Shah PM, Schaefer V et al. (1987) Intraligamentäre Anästhesie mit druckbegrenzender Spritze. Quintessenz 8: 1329–1336

102.

Idsoe O, Guthe T, Willcox RR, Weck AL (1968) Nature and extent of penicillin side-reactions, with particular reference to fatalities from anaphylactic shock. Bull Word Health Organ 38: 159–188

103.

Ahlstedt S (1984) Penicillin allergy – can the incidence be reduced? Allergy 39: 151–164CrossRefPubMed

Titel: Prophylaxe der infektiösen Endokarditis
verfasst von: Christoph K. Naber
Bilal Al-Nawas
Helmut Baumgartner
Hans-Jürgen Becker
Michael Block
Raimund Erbel
Georg Ertl
Ursula Flückiger
Damian Franzen
Christa Gohlke-Bärwolf
Rainer Gattringer
Wolfgang Graninger
Werner Handrick
Matthias Herrmann
Matthias Herrmann
Ruth Heying
Dieter Horstkotte
Andres Jaussi
Peter Kern
Hans-Heiner Kramer
Sebastian Kühl
Philipp M. Lepper
Rainer G. Leyh
Hartmut Lode
Uwe Mehlhorn
Philippe Moreillon
Andreas Mügge
Reinier Mutters
Jörg Niebel
Georg Peters
Raphael Rosenhek
Achim A. Schmaltz
Harald Seifert
Pramod M. Shah
Helmut Sitter
Wilfried Wagner
Karl Werdan
Michel Zuber
Publikationsdatum: 01.12.2007
Verlag: Springer-Verlag
Erschienen in: Die Kardiologie / Ausgabe 4/2007
Print ISSN: 2731-7129
Elektronische ISSN: 2731-7137
DOI: https://doi.org/10.1007/s12181-007-0037-x

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

Mehr Lebenszeit mit Abemaciclib bei fortgeschrittenem Brustkrebs?

24.05.2024 Mammakarzinom Nachrichten

In der MONARCHE-3-Studie lebten Frauen mit fortgeschrittenem Hormonrezeptor-positivem, HER2-negativem Brustkrebs länger, wenn sie zusätzlich zu einem nicht steroidalen Aromatasehemmer mit Abemaciclib behandelt wurden; allerdings verfehlte der numerische Zugewinn die statistische Signifikanz.

ADT zur Radiatio nach Prostatektomie: Wenn, dann wohl länger

24.05.2024 Prostatakarzinom Nachrichten

Welchen Nutzen es trägt, wenn die Strahlentherapie nach radikaler Prostatektomie um eine Androgendeprivation ergänzt wird, hat die RADICALS-HD-Studie untersucht. Nun liegen die Ergebnisse vor. Sie sprechen für länger dauernden Hormonentzug.

„Überwältigende“ Evidenz für Tripeltherapie beim metastasierten Prostata-Ca.

22.05.2024 Prostatakarzinom Nachrichten

Patienten mit metastasiertem hormonsensitivem Prostatakarzinom sollten nicht mehr mit einer alleinigen Androgendeprivationstherapie (ADT) behandelt werden, mahnt ein US-Team nach Sichtung der aktuellen Datenlage. Mit einer Tripeltherapie haben die Betroffenen offenbar die besten Überlebenschancen.

So sicher sind Tattoos: Neue Daten zur Risikobewertung

22.05.2024 Melanom Nachrichten

Das größte medizinische Problem bei Tattoos bleiben allergische Reaktionen. Melanome werden dadurch offensichtlich nicht gefördert, die Farbpigmente könnten aber andere Tumoren begünstigen.

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Die Highlights vom Kongress des American College of Cardiology 2024

Springer Medizin

Auszug

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 4/2007

Fortbildung und Wissenschaft mit den Zeitschriften der DGK

Mitralklappenendokarditis

17-Jährige Patientin mit Gesichtserythem, Niereninsuffizienz und Verdacht auf Mitralklappenendokarditis

Viel Neues beim AHA 2007 in Orlando

Bedeutung der MRT in der Diagnostik der arrhythmogenen rechtsventrikulären Kardiomyopathie