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Erschienen in: CNS Drugs 2/2013

01.02.2013 | Therapy in Practice

Refractory Trigeminal Neuralgia

Non-Surgical Treatment Options

verfasst von: Giorgio Cruccu, Andrea Truini

Erschienen in: CNS Drugs | Ausgabe 2/2013

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Abstract

The guidelines on trigeminal neuralgia management published by the American Academy of Neurology (AAN) and the European Federation of Neurological Societies (EFNS) recommended that patients unresponsive to carbamazepine or oxcarbazepine be offered the surgical option. However, because some patients may not be willing to resort to surgery, we searched the literature for treatment in refractory trigeminal neuralgia. We found other oral treatments, intranasal spray, subcutaneous injections, various kinds of peripheral nerve blocks and injections of botulinum toxin. On the basis of the available evidence we suggest that no oral treatment other than carbamazepine or oxcarbazepine is useful. Among the other options, there is increasingly strong evidence that botulinum toxin injections are efficacious and may be offered before surgery or to those unwilling to undergo surgery.
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Metadaten
Titel
Refractory Trigeminal Neuralgia
Non-Surgical Treatment Options
verfasst von
Giorgio Cruccu
Andrea Truini
Publikationsdatum
01.02.2013
Verlag
Springer International Publishing AG
Erschienen in
CNS Drugs / Ausgabe 2/2013
Print ISSN: 1172-7047
Elektronische ISSN: 1179-1934
DOI
https://doi.org/10.1007/s40263-012-0023-0

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