Substantial depletion of Langerhans cells leads to their replenishment by bone marrow–derived precursors that access the epidermis through hair follicles, a site of crucial chemokine production.
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Heath, W., Mueller, S. Hair follicles: gatekeepers to the epidermis. Nat Immunol 13, 715–717 (2012). https://doi.org/10.1038/ni.2374
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DOI: https://doi.org/10.1038/ni.2374
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