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Critical Care
Erschienen in: Critical Care 5/2005

01.10.2005 | Review

The epidemiology and modern management of traumatic hemorrhage: US and international perspectives

verfasst von: David S Kauvar, Charles E Wade

Erschienen in: Critical Care | Sonderheft 5/2005

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Abstract

Trauma is a worldwide problem, with severe and wide ranging consequences for individuals and society as a whole. Hemorrhage is a major contributor to the dilemma of traumatic injury and its care. In this article we describe the international epidemiology of traumatic injury, its causes and its consequences, and closely examine the role played by hemorrhage in producing traumatic morbidity and mortality. Emphasis is placed on defining situations in which traditional methods of hemorrhage control often fail. We then outline and discuss modern principles in the management of traumatic hemorrhage and explore developing changes in these areas. We conclude with a discussion of outcome measures for the injured patient within the context of the epidemiology of traumatic injury.
Literatur
1.
Cinat ME, Wilson SE, Lush S, Atkins C: Significant correlation of trauma epidemiology with the economic conditions of a community. Arch Surg 2004, 139: 1350-1355. 10.1001/archsurg.139.12.1350CrossRef
2.
Peden M, McGee K, Sharma G: The Injury Chart Book: a Graphical Overview of the Global Burden of Injuries. Geneva: World Health Organization; 2002.
3.
Peden M: World Report on Road Traffic Injury Prevention: Summary. Geneva: World Health Organization; 2004.
4.
Krug E, Dahlberg L, Zwi A, Mercy J, Lozano R, Eds: World Report on Violence and Health. Geneva: World Health Organization; 2002.
5.
Centers for Disease Control and Prevention: Web-based Injury Statistics Query and Reporting System (WISQARS). Atlanta: US Department of Health and Human Services, CDC, National Center for Injury Prevention and Control; 2002.
6.
Centers for Disease Control and Prevention: Medical expenditures attributable to injuries – United States, 2000. MMWR Morb Mortal Wkly Rep 2004, 53: 1-4.
7.
Pape HC, Grotz M, Schwermann T, Ruchholtz S, Lefering R, Rieger M, Troger M, Graf von der Schulenburg JM, Krettek C, AG Polytrauma der DGU: The development of a model to calculate the cost of care for the severely injured – an initiative of the Trauma Register of the DGU [in German]. Unfallchirurg 2003, 106: 348-357. 10.1007/s00113-003-0605-xCrossRef
8.
Shackford SR, Mackersie RC, Hoyt DB, Baxt WG, Eastman AB, Hammill FN, Knotts FB, Virgilio RW: Impact of a trauma system on outcome of severely injured patients. Arch Surg 1987, 122: 523-527.CrossRef
9.
Holbrook TL, Anderson JP, Sieber WJ, Browner D, Hoyt DB: Outcome after major trauma: 12-month and 18-month follow-up results from the Trauma Recovery Project. J Trauma 1999, 46: 765-771.CrossRef
10.
Vazquez MG, Rivera FR, Perez AA, Gonzalez CA, Fernandez ME, Navarrete NP: Analysis of quality of life in polytraumatized patients two years after discharge from an intensive care unit. J Trauma 1996, 41: 326-332.CrossRef
11.
Baker CC, Oppenheimer L, Stephens B, Lewis FR, Trunkey DD: Epidemiology of trauma deaths. Am J Surg 1980, 140: 144-150. 10.1016/0002-9610(80)90431-6CrossRef
12.
Potenza BM, Hoyt DB, Coimbra R, Fortlage D, Holbrook T, Hollingsworth-Fridlund P: The epidemiology of serious and fatal injury in San Diego County over an 11-year period. J Trauma 2004, 56: 68-75.CrossRef
13.
Sauaia A, Moore FA, Moore EE, Moser KS, Brennan R, Read RA, Pons PT: Epidemiology of trauma deaths: a reassessment. J Trauma 1995, 38: 185-193.CrossRef
14.
Shackford SR, Mackersie RC, Holbrook TL, Davis JW, Hollingsworth-Fridlund P, Hoyt DB, Wolf PL: The epidemiology of traumatic death. A population-based analysis. Arch Surg 1993, 128: 571-575.CrossRef
15.
Acosta JA, Yang JC, Winchell RJ, Simons RK, Fortlage DA, Hollingsworth-Fridlund P, Hoyt DB: Lethal injuries and time to death in a level I trauma center. J Am Coll Surg 1998, 186: 528-533. 10.1016/S1072-7515(98)00082-9CrossRef
16.
Stewart RM, Myers JG, Dent DL, Ermis P, Gray GA, Villarreal R, Blow O, Woods B, McFarland M, Garavaglia J, et al.: Seven hundred fifty-three consecutive deaths in a level I trauma center: the argument for injury prevention. J Trauma 2003, 54: 66-70.CrossRef
17.
Franklin GA, Boaz PW, Spain DA, Lukan JK, Carrillo EH, Richardson JD: Prehospital hypotension as a valid indicator of trauma team activation. J Trauma 2000, 48: 1034-1037.CrossRef
18.
Heckbert SR, Vedder NB, Hoffman W, Winn RK, Hudson LD, Jurkovich GJ, Copass MK, Harlan JM, Rice CL, Maier RV: Outcome after hemorrhagic shock in trauma patients. J Trauma 1998, 45: 545-549.CrossRef
19.
Durham RM, Moran JJ, Mazuski JE, Shapiro MJ, Baue AE, Flint LM: Multiple organ failure in trauma patients. J Trauma 2003, 55: 608-616.CrossRef
20.
Malone DL, Dunne J, Tracy JK, Putnam AT, Scalea TM, Napolitano LM: Blood transfusion, independent of shock severity, is associated with worse outcome in trauma. J Trauma 2003, 54: 898-905.CrossRef
21.
Moore FA, Moore EE, Sauaia A: Blood transfusion. An independent risk factor for postinjury multiple organ failure. Arch Surg 1997, 132: 620-624.CrossRef
22.
Sauaia A, Moore FA, Moore EE, Haenel JB, Read RA, Lezotte DC: Early predictors of postinjury multiple organ failure. Arch Surg 1994, 129: 39-45.CrossRef
23.
Hoyt DB, Bulger EM, Knudson MM, Morris J, Ierardi R, Sugerman HJ, Shackford SR, Landercasper J, Winchell RJ, Jurkovich G: Death in the operating room: an analysis of a multi-center experience. J Trauma 1994, 37: 426-432.CrossRef
24.
Mattox KL, Feliciano DV, Moore EE: Trauma. New York: McGraw-Hill, Health Professions Division; 2000.
25.
Ceylan S, Kuzeyli K, Ilbay K, Akturk F: Non operative management of acute extradural hematomas in children. J Neurosurg Sci 1992, 36: 85-88.
26.
Mandera M, Zralek C, Krawczyk I, Zycinski A, Wencel T, Bazowski P: Surgery or conservative treatment in children with traumatic intracerebral haematoma. Childs Nerv Syst 1999, 15: 267-269. 10.1007/s003810050389CrossRef
27.
Mathew P, Oluoch-Olunya DL, Condon BR, Bullock R: Acute subdural haematoma in the conscious patient: outcome with initial non-operative management. Acta Neurochir (Wien) 1993, 121: 100-108. 10.1007/BF01809258CrossRef
28.
Wong CW: The CT criteria for conservative treatment – but under close clinical observation – of posterior fossa epidural haematomas. Acta Neurochir (Wien) 1994, 126: 124-127. 10.1007/BF01476421CrossRef
29.
Wong CW: Criteria for conservative treatment of supratentorial acute subdural haematomas. Acta Neurochir (Wien) 1995, 135: 38-43. 10.1007/BF02187756CrossRef
30.
Wong CW: CT and clinical criteria for conservative treatment of supratentorial traumatic intracerebral haematomas. Acta Neurochir (Wien) 1995, 135: 131-135. 10.1007/BF02187756CrossRef
31.
Mina AA, Knipfer JF, Park DY, Bair HA, Howells GA, Bendick PJ: Intracranial complications of preinjury anticoagulation in trauma patients with head injury. J Trauma 2002, 53: 668-672.CrossRef
32.
Mina AA, Bair HA, Howells GA, Bendick PJ: Complications of preinjury warfarin use in the trauma patient. J Trauma 2003, 54: 842-847.CrossRef
33.
Chen L, Bracey AW, Radovancevic R, Cooper JR Jr, Collard CD, Vaughn WK, Nussmeier NA: Clopidogrel and bleeding in patients undergoing elective coronary artery bypass grafting. J Thorac Cardiovasc Surg 2004, 128: 425-431. 10.1016/j.jtcvs.2004.02.019CrossRef
34.
Englberger L, Faeh B, Berdat PA, Eberli F, Meier B, Carrel T: Impact of clopidogrel in coronary artery bypass grafting. Eur J Cardiothorac Surg 2004, 26: 96-101. 10.1016/j.ejcts.2004.03.030CrossRef
35.
Slappendel R, Weber EW, Benraad B, Dirksen R, Bugter ML: Does ibuprofen increase perioperative blood loss during hip arthroplasty? Eur J Anaesthesiol 2002, 19: 829-831.CrossRef
36.
Demetriades D, Constantinou C, Salim A, Velmahos G, Rhee P, Chan L: Liver cirrhosis in patients undergoing laparotomy for trauma: effect on outcomes. J Am Coll Surg 2004, 199: 538-542. 10.1016/j.jamcollsurg.2004.06.017CrossRef
37.
Tinkoff G, Rhodes M, Diamond D, Lucke J: Cirrhosis in the trauma victim. Effect on mortality rates. Ann Surg 1990, 211: 172-177.CrossRef
38.
Rubin R, Rand ML: Alcohol and platelet function. Alcohol Clin Exp Res 1994, 18: 105-110.CrossRef
39.
Brohi K, Singh J, Heron M, Coats T: Acute traumatic coagulopathy. J Trauma 2003, 54: 1127-1130.CrossRef
40.
Lynn M, Jeroukhimov I, Klein Y, Martinowitz U: Updates in the management of severe coagulopathy in trauma patients. Intensive Care Med 2002,28(suppl 2):S241-S247. 10.1007/s00134-002-1471-7CrossRef
41.
MacLeod JB, Lynn M, McKenney MG, Cohn SM, Murtha M: Early coagulopathy predicts mortality in trauma. J Trauma 2003, 55: 39-44.CrossRef
42.
Ferrara A, MacArthur JD, Wright HK, Modlin IM, McMillen MA: Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion. Am J Surg 1990, 160: 515-518.CrossRef
43.
Staab DB, Sorensen VJ, Fath JJ, Raman SB, Horst HM, Obeid FN: Coagulation defects resulting from ambient temperature-induced hypothermia. J Trauma 1994, 36: 634-638.CrossRef
44.
Cosgriff N, Moore EE, Sauaia A, Kenny-Moynihan M, Burch JM, Galloway B: Predicting life-threatening coagulopathy in the massively transfused trauma patient: hypothermia and acidoses revisited. J Trauma 1997, 42: 857-861.CrossRef
45.
Ferrara A, MacArthur JD, Wright HK, Modlin IM, McMillen MA: Hypothermia and acidosis worsen coagulopathy in the patient requiring massive transfusion. Am J Surg 1990, 160: 515-518.CrossRef
46.
Watts DD, Trask A, Soeken K, Perdue P, Dols S, Kaufmann C: Hypothermic coagulopathy in trauma: effect of varying levels of hypothermia on enzyme speed, platelet function, and fibrinolytic activity. J Trauma 1998, 44: 846-854.CrossRef
47.
Shackford SR, Hollingworth-Fridlund P, Cooper GF, Eastman AB: The effect of regionalization upon the quality of trauma care as assessed by concurrent audit before and after institution of a trauma system: a preliminary report. J Trauma 1986, 26: 812-820.CrossRef
48.
West JG, Trunkey DD, Lim RC: Systems of trauma care. A study of two counties. Arch Surg 1979, 114: 455-460.CrossRef
49.
Arreola-Risa C, Mock CN, Lojero-Wheatly L, de la CO, Garcia C, Canavati-Ayub F, Jurkovich GJ: Low-cost improvements in pre-hospital trauma care in a Latin American city. J Trauma 2000, 48: 119-124.CrossRef
50.
Benitez FL, Pepe PE: Role of the physician in prehospital management of trauma: North American perspective. Curr Opin Crit Care 2002, 8: 551-558. 10.1097/00075198-200212000-00012CrossRef
51.
Dick WF: Anglo-American vs. Franco-German emergency medical services system. Prehospital Disaster Med 2003, 18: 29-35.CrossRef
52.
Ummenhofer W, Scheidegger D: Role of the physician in pre-hospital management of trauma: European perspective. Curr Opin Crit Care 2002, 8: 559-565. 10.1097/00075198-200212000-00013CrossRef
53.
American College of Surgeons. Committee on Trauma: PHTLS: Basic and Advanced Prehospital Trauma Life Support. Chicago: American College of Surgeons; 2003.
54.
American College of Surgeons: ATLS, Advanced Trauma Life Support. Chicago, IL: The College; 2004.
55.
Cannon W, Fraser J, Cowell E: The preventive treatment of wound shock. JAMA 1918, 618-621.
56.
Bickell WH, Wall MJ Jr, Pepe PE, Martin RR, Ginger VF, Allen MK, Mattox KL: Immediate versus delayed fluid resuscitation for hypotensive patients with penetrating torso injuries. N Engl J Med 1994, 331: 1105-1109. 10.1056/NEJM199410273311701CrossRef
57.
Burris D, Rhee P, Kaufmann C, Pikoulis E, Austin B, Eror A, DeBraux S, Guzzi L, Leppaniemi A: Controlled resuscitation for uncontrolled hemorrhagic shock. J Trauma 1999, 46: 216-223.CrossRef
58.
Capone AC, Safar P, Stezoski W, Tisherman S, Peitzman AB: Improved outcome with fluid restriction in treatment of uncontrolled hemorrhagic shock. J Am Coll Surg 1995, 180: 49-56.
59.
Kowalenko T, Stern S, Dronen S, Wang X: Improved outcome with hypotensive resuscitation of uncontrolled hemorrhagic shock in a swine model. J Trauma 1992, 33: 349-353.CrossRef
60.
Mapstone J, Roberts I, Evans P: Fluid resuscitation strategies: a systematic review of animal trials. J Trauma 2003, 55: 571-589.CrossRef
61.
Sondeen JL, Coppes VG, Holcomb JB: Blood pressure at which rebleeding occurs after resuscitation in swine with aortic injury. J Trauma 2003, 54: S110-S117.CrossRef
62.
Stern SA: Low-volume fluid resuscitation for presumed hemorrhagic shock: helpful or harmful? Curr Opin Crit Care 2001, 7: 422-430. 10.1097/00075198-200112000-00009CrossRef
63.
Deb S, Martin B, Sun L, Ruff P, Burris D, Rich N, DeBreux S, Austin B, Rhee P: Resuscitation with lactated Ringer's solution in rats with hemorrhagic shock induces immediate apoptosis. J Trauma 1999, 46: 582-588.CrossRef
64.
Deb S, Sun L, Martin B, Talens E, Burris D, Kaufmann C, Rich N, Rhee P: Lactated ringer's solution and hetastarch but not plasma resuscitation after rat hemorrhagic shock is associated with immediate lung apoptosis by the up-regulation of the Bax protein. J Trauma 2000, 49: 47-53.CrossRef
65.
Rhee P, Koustova E, Alam HB: Searching for the optimal resuscitation method: recommendations for the initial fluid resuscitation of combat casualties. J Trauma 2003, 54: S52-S62.CrossRef
66.
Mattox KL, Maningas PA, Moore EE, Mateer JR, Marx JA, Aprahamian C, Burch JM, Pepe PE: Prehospital hypertonic saline/dextran infusion for post-traumatic hypotension. The U.S.A. Multicenter Trial. Ann Surg 1991, 213: 482-491.CrossRef
67.
Boldt J: Fluid choice for resuscitation of the trauma patient: a review of the physiological, pharmacological, and clinical evidence. Can J Anaesth 2004, 51: 500-513.CrossRef
68.
Protheroe R, Nolan J: Which fluid to give? Trauma 2001, 3: 151-160. 10.1191/146040801717155541CrossRef
69.
Rizoli SB: Crystalloids and colloids in trauma resuscitation: a brief overview of the current debate. J Trauma 2003, 54: S82-S88.
70.
Whinney RR, Cohn SM, Zacur SJ: Fluid resuscitation for trauma patients in the 21st century. Curr Opin Crit Care 2000, 6: 395-400. 10.1097/00075198-200012000-00004CrossRef
71.
Greenburg AG, Kim HW: Hemoglobin-based oxygen carriers. Crit Care 2004,8(Suppl 2):S61-S64. 10.1186/cc2455CrossRef
72.
Proctor KG: Blood substitutes and experimental models of trauma. J Trauma 2003, 54: S106-S109.
73.
Tisherman SA, Barie P, Bokhari F, Bonadies J, Daley B, Diebel L, Eachempati SR, Kurek S, Luchette F, Carlos PJ, et al.: Clinical practice guideline: endpoints of resuscitation. J Trauma 2004, 57: 898-912.CrossRef
74.
Reed RL, Johnson TD, Hudson JD, Fischer RP: The disparity between hypothermic coagulopathy and clotting studies. J Trauma 1992, 33: 465-470.CrossRef
75.
Kaufmann CR, Dwyer KM, Crews JD, Dols SJ, Trask AL: Usefulness of thromboelastography in assessment of trauma patient coagulation. J Trauma 1997, 42: 716-720.CrossRef
Metadaten
Titel
The epidemiology and modern management of traumatic hemorrhage: US and international perspectives
verfasst von
David S Kauvar
Charles E Wade
Publikationsdatum
01.10.2005
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe Sonderheft 5/2005
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc3779

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