Erschienen in:
01.09.2007 | Review
Manganese accumulation in the brain: MR imaging
verfasst von:
A. Uchino, T. Noguchi, K. Nomiyama, Y. Takase, T. Nakazono, J. Nojiri, S. Kudo
Erschienen in:
Neuroradiology
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Ausgabe 9/2007
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Abstract
Manganese (Mn) accumulation in the brain is detected as symmetrical high signal intensity in the globus pallidi on T1-weighted MR images without an abnormal signal on T2-weighted images. In this review, we present several cases of Mn accumulation in the brain due to acquired or congenital diseases of the abdomen including hepatic cirrhosis with a portosystemic shunt, congenital biliary atresia, primary biliary cirrhosis, congenital intrahepatic portosystemic shunt without liver dysfunction, Rendu-Osler-Weber syndrome with a diffuse intrahepatic portosystemic shunt, and patent ductus venosus. Other causes of Mn accumulation in the brain are Mn overload from total parenteral nutrition and welding-related Mn intoxication.