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Arthritis Research & Therapy
Erschienen in: Arthritis Research & Therapy 3/2009

01.06.2009 | Review

Molecular therapies for systemic lupus erythematosus: clinical trials and future prospects

verfasst von: Fanny Monneaux, Sylviane Muller

Erschienen in: Arthritis Research & Therapy | Ausgabe 3/2009

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Abstract

The prognosis of patients with systemic lupus erythematosus has greatly improved since treatment regimens combining corticosteroids and immunosuppressive medications have been widely adopted in therapeutic strategies given to these patients. Immune suppression is evidently efficient but also leads to higher susceptibility to infectious and malignant diseases. Toxic effects and sometimes unexpectedly dramatic complications of current therapies have been progressively reported. Identifying novel molecular targets therefore remains an important issue in the treatment of lupus. The aim of this review article is to highlight emerging pharmacological options and new therapeutic avenues for lupus with a particular focus on non-antibody molecular strategies.
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Metadaten
Titel
Molecular therapies for systemic lupus erythematosus: clinical trials and future prospects
verfasst von
Fanny Monneaux
Sylviane Muller
Publikationsdatum
01.06.2009
Verlag
BioMed Central
Erschienen in
Arthritis Research & Therapy / Ausgabe 3/2009
Elektronische ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar2711

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