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08.02.2016 | Mini-Review

Novel concepts of immune responses to chemicals in allergic contact dermatitis

verfasst von: Stefan F. Martin

Erschienen in: Allergo Journal | Ausgabe 1/2016

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Summary

Allergic contact dermatitis (ACD) is caused by chemical-reactive T cells. A prerequisite for their activation is the induction of skin inflammation by contact allergens. This requires the activation of signaling pathways of the innate immune system which are also activated in anti-infectious immune responses. The mechanistic basis of the essential innate inflammatory response to chemical allergens and its implications for pathogenesis, therapy, and immunotoxicology will be discussed in this minireview.

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Titel: Novel concepts of immune responses to chemicals in allergic contact dermatitis
verfasst von: Stefan F. Martin
Publikationsdatum: 08.02.2016
Verlag: Springer Medizin
Erschienen in: Allergo Journal / Ausgabe 1/2016
Print ISSN: 0941-8849
Elektronische ISSN: 2195-6405
DOI: https://doi.org/10.1007/s15007-016-1014-0

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