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Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 4/2011

01.04.2011 | Sports Medicine

Platelet-rich plasma (PRP) to treat sports injuries: evidence to support its use

verfasst von: Elizaveta Kon, Giuseppe Filardo, Alessandro Di Martino, Maurilio Marcacci

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 4/2011

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Abstract

Tissue repair in musculoskeletal lesions is often a slow and sometimes incomplete process. In sports patients or professional athletes, the impact of musculoskeletal lesions on life and work is great, and the fast recovery of full efficiency and return to competition is of primary importance. The clinical improvement offered by available treatments is not always sufficient for highly demanding patients to return to their previous level of activity. The search for a minimally invasive solution to improve the status of the chondral surface of the injured joint is therefore highly desirable, especially in these patients. Platelet-rich plasma (PRP) is a procedure that allows to obtain a natural concentration of autologous growth factors. The attractive possibility to use the patients’ own growth factors to enhance reparative process in tissues with low healing potential, the promising preliminary clinical findings and the safety of these methods, explain the wide application of this biological approach. The aim of this review is to analyse the existing published studies to look for scientific evidence in preclinical studies or in the results obtained through PRP application in humans that supports the efficacy of PRP and its use for the treatment of tendinous, ligamentous, cartilaginous and muscular injuries. The analysis of the literature shows promising preclinical results but contradictory clinical findings for the treatment of sport injuries. High-quality studies are required to confirm these preliminary results and provide scientific evidence to support its use.
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Metadaten
Titel
Platelet-rich plasma (PRP) to treat sports injuries: evidence to support its use
verfasst von
Elizaveta Kon
Giuseppe Filardo
Alessandro Di Martino
Maurilio Marcacci
Publikationsdatum
01.04.2011
Verlag
Springer-Verlag
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 4/2011
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-010-1306-y

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