Background
Methods
Data source and study participants
Measurement
Cancer type and age at diagnosis
General health
Social health
Physical health
Psychological health
Statistical analysis
Results
Study participants
Characteristics | NHW Weighted proportiona (SE) | AA Weighted proportiona (SE) | Hispanic Weighted proportiona (SE) | Asian Weighted proportiona (SE) | p value |
---|---|---|---|---|---|
Age at survey, years | 48.96 (1.09) | 48.12 (2.09) | 41.32 (1.47) | 43.56 (0.68) | < 0.01 |
Gender | 0.02 | ||||
Male | 28.5 (0.01) | 11.1 (0.01) | 14.1 (0.01) | 23.6 (0.01) | |
Female | 71.5 (0.01) | 88.9 (0.01) | 85.9 (0.01) | 76.4 (0.01) | |
Age at diagnosis | 29.40 (0.41) | 29.61 (0.81) | 28.57 (0.83) | 33.00 (0.37) | < 0.01 |
Age at diagnosis categories | |||||
15–25 years | 25.6 (0.02) | 24.3 (0.01) | 31.2 (0.02) | 9.2 (0.01) | |
26–30 years | 30.7 (0.02) | 33.5 (0.02) | 28.9 (0.02) | 12.6 (0.01) | |
31–35 years | 25.4 (0.02) | 26.2 (0.02) | 19.8 (0.01) | 39.9 (0.02) | |
36–39 years | 18.3 (0.01) | 16.0 (0.01) | 20.1 (0.01) | 38.3 (0.02) | |
Cancer type | < 0.01 | ||||
Gynecologic/Genitourinary | 40.2 (0.02) | 50.5 (0.02) | 61.2 (0.02) | 32.3 (0.02) | |
Skin/Melanoma | 34.7 (0.02) | 2.4 (0.01) | 5.9 (0.01) | 0.4 (0.01) | |
Thyroid | 5.8 (0.01) | 4.9 (0.01) | 5.6 (0.01) | 25.2 (0.02) | |
Hematologic | 4.2 (0.01) | 10.4 (0.01) | 5.2 (0.01) | 4.8 (0.01) | |
Breast | 2.7 (0.01) | 13.9 (0.01) | 7.0 (0.01) | 13.0 (0.01) | |
Colorectal | 2.7 (0.01) | 3.5 (0.01) | 0.0 (0.00) | 3.8 (0.01) | |
Liver | 0.8 (0.01) | 3.5 (0.01) | 0.0 (0.00) | 0.6 (0.01) | |
Lung | 0.5 (0.01) | 0.0 (0.00) | 0.0 (0.00) | 0.0 (0.00) | |
Stomach | 0.0 (0.00) | 1.9 (0.01) | 0.0 (0.00) | 7.0 (0.01) | |
Others | 8.4 (0.01) | 9.0 (0.01) | 15.1 (0.01) | 12.9 (0.01) | |
Time since diagnosis, years | 19.56 (0.99) | 18.51 (1.98) | 12.76 (1.18) | 10.57 (0.57) | < 0.01 |
General and social health and healthy behavior in AYA survivors by race/ethnicity
NHW aOR (95% CI)a | AA aOR (95% CI)a | Hispanic aOR (95% CI)a | Asian aOR (95% CI)a | |
---|---|---|---|---|
General health, poor/fair | reference | 1.09 (0.92–1.28) | 1.15 (1.00–1.32) | 1.06 (0.96–1.18) |
Social health | ||||
Education, less than high school graduate | reference | 0.99 (0.88–1.11) | 1.23 (1.07–1.40) | 1.08 (1.00–1.16) |
Marital status, non-coupled | reference | 1.35 (1.15–1.60) | 1.08 (0.95–1.23) | 0.97 (0.88–1.08) |
Yearly household income, less than $20,000 | reference | 1.10 (0.95–1.27) | 1.16 (1.01–1.33) | 1.04 (0.97–1.11) |
Current job status, unemployed | reference | 1.01 (0.85–1.21) | 0.89 (0.80–0.99) | 1.07 (0.97–1.19) |
Health behavior | ||||
Smoking status, former/current | reference | 0.97 (0.81–1.15) | 0.76 (0.66–0.87) | 0.76 (0.68–0.84) |
Alcohol status, former/current | reference | 1.19 (0.88–1.60) | 0.82 (0.68–0.98) | 1.21 (1.05–1.40) |
Comorbidities, reproductive and psychological health in AYA survivors by race/ethnicity
NHW aOR (95% CI)a | AA aOR (95% CI)a | Hispanic aOR (95% CI)a | Asian aOR (95% CI)a | |
---|---|---|---|---|
Comorbidities | ||||
Cardiovascular disease | ||||
Hypertension | reference | 1.18 (1.03–1.36) | 0.95 (0.86–1.04) | 0.91 (0.83–0.99) |
Stroke | reference | 1.09 (0.99–1.20) | 0.99 (0.95–1.03) | 0.97 (0.94–0.99) |
Angina/angina pectoris | reference | 1.00 (0.93–1.06) | 0.96 (0.93–1.00) | 0.97 (0.93–1.01) |
Myocardial infarction | reference | 1.00 (0.93–1.08) | 0.98 (0.94–1.02) | 0.96 (0.93–0.99) |
Obesity | reference | 1.14 (0.98–1.32) | 1.11 (0.96–1.28) | 0.94 (0.84–1.06) |
Dyslipidemia | reference | 0.99 (0.87–1.13) | 0.91 (0.84–0.99) | 0.89 (0.83–0.96) |
DM | reference | 1.06 (0.97–1.15) | 1.11 (1.02–1.20) | 1.03 (0.98–1.09) |
Non-cardiovascular disease | ||||
Arthritis | reference | 1.03 (0.88–1.20) | 0.88 (0.79–0.98) | 0.75 (0.69–0.82) |
Thyroid disease | reference | 0.97 (0.86–1.08) | 1.02 (0.92–1.13) | 0.85 (0.78–0.93) |
Asthma | reference | 0.89 (0.77–1.04) | 0.97 (0.85–1.10) | 0.79 (0.73–0.87) |
Reproductive healthb | ||||
History of pregnant, yes | reference | 1.08 (0.96–1.21) | 1.08 (0.96–1.21) | 1.00 (0.90–1.10) |
History of birth, yes | reference | 1.05 (0.91–1.21) | 1.08 (0.96–1.22) | 0.99 (0.90–1.10) |
Psychological health | ||||
Daily activity limitation due to emotional problem, yes | reference | 0.75 (0.39–1.42) | 0.77 (0.46–1.28) | 0.65 (0.47–0.88) |
Depression, PHQ-9 ≥ 10c | reference | 1.00 (0.95–1.07) | 0.97 (0.94–1.01) | 1.07 (0.99–1.17) |
Suicide ideation, yes | reference | 0.97 (0.93–1.06) | 0.99 (0.93–1.06) | 1.07 (1.01–1.14) |
Social, physical, and psychological health in AYA survivors and matched general by race/ethnicity
AYA vs. age, sex, year, and race matcheda general | P for interaction | ||||
---|---|---|---|---|---|
NHW aOR (95% CI)a | AA aOR (95% CI)a | Hispanic aOR (95% CI)a | Asian aOR (95% CI)a | ||
General health, poor/fair | 1.59 (1.17–2.15) | 1.30 (0.58–2.78) | 1.35 (0.79–2.30) | 2.93 (2.27–3.77) | < 0.01 |
Social health | |||||
Education, less than high school graduate | 1.14 (0.81–1.58) | 0.71 (0.25–1.73) | 0.63 (0.38–1.03) | 1.13 (0.80–1.59) | 0.07 |
Marital status, non-coupled | 1.33 (1.04–1.71) | 1.15 (0.58–2.37) | 1.49 (0.91–2.44) | 0.95 (0.73–1.22) | 0.14 |
Yearly household income, less than $20,000 | 1.09 (0.80–1.46) | 0.97 (0.44–2.03) | 1.29 (0.75–2.18) | 1.02 (0.74–1.38) | 0.82 |
Current job status, unemployed | 1.34 (1.03–1.73) | 1.38 (0.69–2.75) | 0.63 (0.37–1.06) | 1.10 (0.87–1.38) | 0.08 |
Physical health | |||||
Health behavior | |||||
Smoking status, former/current | 1.62 (1.26–2.07) | 1.79 (0.90–3.58) | 0.89 (0.49–1.57) | 0.92 (0.67–1.24) | < 0.01 |
Alcohol status, former/current | 1.27 (0.73–2.26) | 5.51 (1.34–37.53) | 1.16 (0.54–2.50) | 0.90 (0.63–1.31) | < 0.01 |
Reproductive healthb | |||||
History of pregnant, yes | 1.48 (0.94–2.44) | 1.18 (0.29–7.99) | 1.17 (0.42–4.13) | 1.56 (0.97–2.62) | 0.89 |
History of birth, yes | 1.48 (0.94–2.42) | 0.76 (0.21–3.54) | 1.15 (0.42–4.08) | 1.73 (1.11–2.80) | 0.60 |
Comorbidities | |||||
Cardiovascular | |||||
Hypertension | 1.34 (0.99–1.80) | 1.78 (0.77–4.16) | 1.32 (0.68–2.50) | 0.79 (0.56–1.08) | 0.04 |
Stroke | 1.55 (0.86–2.68) | 3.21 (1.02–9.44) | 2.53 (0.52–10.01) | 1.26 (0.28–4.09) | < 0.01 |
Angina/angina pectoris | 1.54 (0.80–2.78) | 1.93 (0.27–9.36) | 0.63 (0.03–3.97) | 3.92 (1.27–11.54) | 0.69 |
Myocardial infarction | 1.93 (1.11–3.26) | 1.91 (0.27–9.36) | 1.42 (0.21–6.05) | 3.88 (0.75–18.02) | 0.20 |
Obesity | 0.88 (0.68–1.14) | 0.79 (0.40–1.57) | 1.11 (0.68–1.82) | 1.08 (0.84–1.38) | 0.59 |
Dyslipidemia | 1.52 (0.99–1.80) | 1.27 (0.77–4.16) | 1.06 (0.68–2.50) | 1.64 (0.56–1.08) | 0.53 |
DM | 1.35 (0.87–2.06) | 1.16 (0.41–2.96) | 1.67 (0.81–3.27) | 1.31 (0.85–1.98) | 0.72 |
Non-cardiovascular | |||||
Arthritis | 1.82 (1.39–2.38) | 2.67 (1.26–5.72) | 2.49 (1.35–4.56) | 1.14 (0.75–1.70) | < 0.01 |
Thyroid disease | 1.31 (0.93–1.83) | 1.89 (0.69–4.71) | 3.81 (2.06–6.97) | 2.57 (1.73–3.76) | < 0.01 |
Asthma | 1.63 (1.22–2.18) | 0.79 (0.31–1.83) | 2.65 (1.42–4.82) | 1.92 (1.09–3.23) | < 0.01 |
Psychological health | |||||
Daily activity limitation due to emotional problem, yes | 0.83 (0.29–2.42) | 1.32 (0.04–32.88) | 0.30 (0.06–1.41) | 2.07 (0.77–5.61) | 0.25 |
Depression, PHQ-9 ≥ 10c | 2.63 (1.21–5.41) | 1.03 (0.05–7.37) | 0.73 (0.04–4.23) | 2.34 (0.99–5.16) | 0.23 |
Suicide ideation, yes | 2.01 (1.14–3.41) | 1.16 (0.23–7.31) | 1.34 (0.38–3.82) | 1.47 (1.01–2.08) | 0.92 |