Skip to main content
Erschienen in: Social Psychiatry and Psychiatric Epidemiology 12/2021

20.04.2021 | Original Paper

Risk of suicide after a self-poisoning episode: a self-controlled case series study

verfasst von: Zhongzhi Xu, Jiannan Yang, Qingpeng Zhang, Paul S. F. Yip

Erschienen in: Social Psychiatry and Psychiatric Epidemiology | Ausgabe 12/2021

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The risk of death from suicide after self-poisoning has been known to be significantly higher as compared to the general population. Nevertheless, the change in suicide risk before and after self-poisoning is still unclear.

Methods

The database of territory-wide medical records collected by the Hospital Authority of Hong Kong was used to identify inpatients who have survived the first-ever self-poisoning but died by suicide between January 1, 2001, and December 31, 2010. A self-controlled case series (“SCCS”) design controlling for time-invariant patient confounders was used to explore the temporal change in suicide risk after the first self-poisoning episode.

Results

During the study period, 227 people in the database died from suicide after surviving one episode of self-poisoning. A significant increase of the risk of suicide in the first 12 months after the first lifetime self-poisoning—Risk Ratio (“RR”) 2.88 (95% CI 1.74–4.76)—was detected. The RR gradually returned to baseline levels after the second post-poisoning period.

Conclusion

By within-person comparison, the net increase of the suicide risk caused by the first self-poisoning was quantitatively modeled, demonstrating that the first lifetime self-poisoning event itself is a modifiable risk factor of subsequent suicide death.
Literatur
1.
Zurück zum Zitat Swanson SA, Colman I (2013) Suicide “contagion”: what we know and what we need to find out. CMAJ 185:870–877CrossRef Swanson SA, Colman I (2013) Suicide “contagion”: what we know and what we need to find out. CMAJ 185:870–877CrossRef
2.
Zurück zum Zitat Centre for Suicide Research and Prevention, Suicide Rate—Centre for Suicide Research and Prevention, Last updated 2019, Accessed on 2019 Centre for Suicide Research and Prevention, Suicide Rate—Centre for Suicide Research and Prevention, Last updated 2019, Accessed on 2019
3.
Zurück zum Zitat Finkelstein Y, MacDonald EM, Hollands S, Sivilotti MLA, Hutson JR, Mamdani MM, Koren G, Juurlink DN, Dormuth CR, Raymond CB, Kozyrskj A, Moride Y, Paterson M (2015) Risk of suicide following deliberate self-poisoning. JAMA Psychiat 72:570–575CrossRef Finkelstein Y, MacDonald EM, Hollands S, Sivilotti MLA, Hutson JR, Mamdani MM, Koren G, Juurlink DN, Dormuth CR, Raymond CB, Kozyrskj A, Moride Y, Paterson M (2015) Risk of suicide following deliberate self-poisoning. JAMA Psychiat 72:570–575CrossRef
4.
Zurück zum Zitat Rockett IRH, Regier MD, Kapusta ND, Coben JH, Miller TR, Hanzlick RL, Todd KH, Sattin RW, Kennedy LW, Kleinig J, Smith GS (2012) Leading causes of unintentional and intentional injury mortality: United States, 2000–2009. Am J Public Health 102:2000–2009CrossRef Rockett IRH, Regier MD, Kapusta ND, Coben JH, Miller TR, Hanzlick RL, Todd KH, Sattin RW, Kennedy LW, Kleinig J, Smith GS (2012) Leading causes of unintentional and intentional injury mortality: United States, 2000–2009. Am J Public Health 102:2000–2009CrossRef
5.
Zurück zum Zitat Langlois S, Morrison P (2002) Suicide deaths and suicide attempts. Health Rep 13:9–22PubMed Langlois S, Morrison P (2002) Suicide deaths and suicide attempts. Health Rep 13:9–22PubMed
6.
Zurück zum Zitat Lam SM, Lau ACW, Yan WW (2010) Over 8 years experience on severe acute poisoning requiring intensive care in Hong Kong, China. China Hum Exp Toxicol 29:757–765CrossRef Lam SM, Lau ACW, Yan WW (2010) Over 8 years experience on severe acute poisoning requiring intensive care in Hong Kong, China. China Hum Exp Toxicol 29:757–765CrossRef
7.
Zurück zum Zitat Finkelstein Y, Macdonald EM, Hollands S, Hutson JR, Sivilotti MLA, Mamdani MM, Koren G, Juurlink DN (2015) Long-term outcomes following self-poisoning in adolescents: a population-based cohort study. Lancet Psychiatry 2:532–539CrossRef Finkelstein Y, Macdonald EM, Hollands S, Hutson JR, Sivilotti MLA, Mamdani MM, Koren G, Juurlink DN (2015) Long-term outcomes following self-poisoning in adolescents: a population-based cohort study. Lancet Psychiatry 2:532–539CrossRef
8.
Zurück zum Zitat Chan EW, Lau WCY, Leung WK, Mok MTC, He Y, Tong TSM, Wong ICK, Gib D (2015) Prevention of dabigatran-related gastrointestinal bleeding with gastroprotective agents: a population-based study. Gastroenterology 149:586-595.e3CrossRef Chan EW, Lau WCY, Leung WK, Mok MTC, He Y, Tong TSM, Wong ICK, Gib D (2015) Prevention of dabigatran-related gastrointestinal bleeding with gastroprotective agents: a population-based study. Gastroenterology 149:586-595.e3CrossRef
9.
Zurück zum Zitat Anderson KM (1986) Rejoinder reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Prev Sch Fail 51:49–51 Anderson KM (1986) Rejoinder reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Prev Sch Fail 51:49–51
10.
Zurück zum Zitat Yip PSF, Yang KCT (2004) A comparison of seasonal variation between suicide deaths and attempts in Hong Kong SAR. J Affect Disord 81:251–257CrossRef Yip PSF, Yang KCT (2004) A comparison of seasonal variation between suicide deaths and attempts in Hong Kong SAR. J Affect Disord 81:251–257CrossRef
11.
Zurück zum Zitat Chai Y, Luo H, Wong GHY, Tang JYM, Lam TC, Wong ICK, Yip PSF (2020) Risk of self-harm after the diagnosis of psychiatric disorders in Hong Kong, 2000–10: a nested case-control study. Lancet Psychiatry 7:135–147CrossRef Chai Y, Luo H, Wong GHY, Tang JYM, Lam TC, Wong ICK, Yip PSF (2020) Risk of self-harm after the diagnosis of psychiatric disorders in Hong Kong, 2000–10: a nested case-control study. Lancet Psychiatry 7:135–147CrossRef
12.
Zurück zum Zitat Man KKC, Coghill D, Chan EW, Lau WCY, Hollis C, Liddle E, Banaschewski T, McCarthy S, Neubert A, Sayal K, Ip P, Schuemie MJ, Sturkenboom MCJM, Sonuga-Barke E, Buitelaar J, Carucci S, Zuddas A, Kovshoff H, Garas P, Nagy P, Inglis SK, Konrad K, Häge A, Rosenthal E, Wong ICK (2017) Association of risk of suicide attempts with methylphenidate treatment. JAMA Psychiat 74:1048–1055CrossRef Man KKC, Coghill D, Chan EW, Lau WCY, Hollis C, Liddle E, Banaschewski T, McCarthy S, Neubert A, Sayal K, Ip P, Schuemie MJ, Sturkenboom MCJM, Sonuga-Barke E, Buitelaar J, Carucci S, Zuddas A, Kovshoff H, Garas P, Nagy P, Inglis SK, Konrad K, Häge A, Rosenthal E, Wong ICK (2017) Association of risk of suicide attempts with methylphenidate treatment. JAMA Psychiat 74:1048–1055CrossRef
13.
Zurück zum Zitat Fransoo R, Martens P, The Need To Know Team, Prior H, Burchill C, Koseva I, Bailly A, Allegro E (2013) The 2013 RHA Indicators Atlas Fransoo R, Martens P, The Need To Know Team, Prior H, Burchill C, Koseva I, Bailly A, Allegro E (2013) The 2013 RHA Indicators Atlas
14.
Zurück zum Zitat Petersen I, Douglas I, Whitaker H (2016) Self controlled case series methods: an alternative to standard epidemiological study designs. BMJ 354:i4515CrossRef Petersen I, Douglas I, Whitaker H (2016) Self controlled case series methods: an alternative to standard epidemiological study designs. BMJ 354:i4515CrossRef
15.
Zurück zum Zitat Whitaker HJ, Farrington CP, Spiessens B, Musonda P (2006) Tutorial in biostatistics: the self-controlled case series method. Stat Med 25:1768–1797CrossRef Whitaker HJ, Farrington CP, Spiessens B, Musonda P (2006) Tutorial in biostatistics: the self-controlled case series method. Stat Med 25:1768–1797CrossRef
16.
Zurück zum Zitat Ghebremichael-Weldeselassie Y, Whitaker HJ, Farrington CP (2016) Flexible modelling of vaccine effect in self-controlled case series models. Biometrical J 58:607–622CrossRef Ghebremichael-Weldeselassie Y, Whitaker HJ, Farrington CP (2016) Flexible modelling of vaccine effect in self-controlled case series models. Biometrical J 58:607–622CrossRef
17.
Zurück zum Zitat Korczyn AD, Halperin I (2009) Depression and dementia. J Neurol Sci 283:139–142CrossRef Korczyn AD, Halperin I (2009) Depression and dementia. J Neurol Sci 283:139–142CrossRef
18.
Zurück zum Zitat Langan SM, Minassian C, Smeeth L, Thomas SL (2014) Risk of stroke following herpes zoster: a self-controlled case-series study. Clin Infect Dis 58:1497–1503CrossRef Langan SM, Minassian C, Smeeth L, Thomas SL (2014) Risk of stroke following herpes zoster: a self-controlled case-series study. Clin Infect Dis 58:1497–1503CrossRef
19.
Zurück zum Zitat Omotesho OA, Falola A, Falola A (2015) Invasive dental treatment and risk for vascular events a self-controlled case series. 7522:215–221 Omotesho OA, Falola A, Falola A (2015) Invasive dental treatment and risk for vascular events a self-controlled case series. 7522:215–221
20.
Zurück zum Zitat Man K, Lau WCY, Coghill D, Besag FMC, Cross JH, Ip P, Wong I (2020) Association between methylphenidate treatment and risk of seizure: a population-based self-controlled case series study. Lancet Child Adolesc Heal 4:435–443CrossRef Man K, Lau WCY, Coghill D, Besag FMC, Cross JH, Ip P, Wong I (2020) Association between methylphenidate treatment and risk of seizure: a population-based self-controlled case series study. Lancet Child Adolesc Heal 4:435–443CrossRef
21.
Zurück zum Zitat Yip P, Pitt D, Wang Y, Wu X, Watson R, Huggins R, Xu Y (2010) Assessing the impact of suicide exclusion periods on life insurance. Crisis 31:217–223CrossRef Yip P, Pitt D, Wang Y, Wu X, Watson R, Huggins R, Xu Y (2010) Assessing the impact of suicide exclusion periods on life insurance. Crisis 31:217–223CrossRef
22.
Zurück zum Zitat Hassanian-Moghaddam H, Sarjami S, Kolahi AA, Carter GL (2011) Postcards in Persia: Randomised controlled trial to reduce suicidal behaviours 12 months after hospital-treated self-poisoning. Br J Psychiatry 198:309–316CrossRef Hassanian-Moghaddam H, Sarjami S, Kolahi AA, Carter GL (2011) Postcards in Persia: Randomised controlled trial to reduce suicidal behaviours 12 months after hospital-treated self-poisoning. Br J Psychiatry 198:309–316CrossRef
23.
Zurück zum Zitat Carter GL, Clover K, Whyte IM, Dawson AH, D’Este C (2013) Postcards from the EDge: 5-year outcomes of a randomised controlled trial for hospital-treated self-poisoning. Br J Psychiatry 202:372–380CrossRef Carter GL, Clover K, Whyte IM, Dawson AH, D’Este C (2013) Postcards from the EDge: 5-year outcomes of a randomised controlled trial for hospital-treated self-poisoning. Br J Psychiatry 202:372–380CrossRef
24.
Zurück zum Zitat Treatment, Cutting and Self-Harm: Warning Signs and Treatment Treatment, Cutting and Self-Harm: Warning Signs and Treatment
25.
Zurück zum Zitat Ghebremichael-Weldeselassie Y, Whitaker HJ, Farrington CP (2017) Spline-based self-controlled case series method. Stat Med 36:3022–3038CrossRef Ghebremichael-Weldeselassie Y, Whitaker HJ, Farrington CP (2017) Spline-based self-controlled case series method. Stat Med 36:3022–3038CrossRef
Metadaten
Titel
Risk of suicide after a self-poisoning episode: a self-controlled case series study
verfasst von
Zhongzhi Xu
Jiannan Yang
Qingpeng Zhang
Paul S. F. Yip
Publikationsdatum
20.04.2021
Verlag
Springer Berlin Heidelberg
Erschienen in
Social Psychiatry and Psychiatric Epidemiology / Ausgabe 12/2021
Print ISSN: 0933-7954
Elektronische ISSN: 1433-9285
DOI
https://doi.org/10.1007/s00127-021-02074-0

Weitere Artikel der Ausgabe 12/2021

Social Psychiatry and Psychiatric Epidemiology 12/2021 Zur Ausgabe

Hörschwäche erhöht Demenzrisiko unabhängig von Beta-Amyloid

29.05.2024 Hörstörungen Nachrichten

Hört jemand im Alter schlecht, nimmt das Hirn- und Hippocampusvolumen besonders schnell ab, was auch mit einem beschleunigten kognitiven Abbau einhergeht. Und diese Prozesse scheinen sich unabhängig von der Amyloidablagerung zu ereignen.

So wirken verschiedene Alkoholika auf den Blutdruck

23.05.2024 Störungen durch Alkohol Nachrichten

Je mehr Alkohol Menschen pro Woche trinken, desto mehr steigt ihr Blutdruck, legen Daten aus Dänemark nahe. Ob es dabei auch auf die Art des Alkohols ankommt, wurde ebenfalls untersucht.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

ADHS-Medikation erhöht das kardiovaskuläre Risiko

16.05.2024 Herzinsuffizienz Nachrichten

Erwachsene, die Medikamente gegen das Aufmerksamkeitsdefizit-Hyperaktivitätssyndrom einnehmen, laufen offenbar erhöhte Gefahr, an Herzschwäche zu erkranken oder einen Schlaganfall zu erleiden. Es scheint eine Dosis-Wirkungs-Beziehung zu bestehen.

Update Psychiatrie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.