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Erschienen in: International Ophthalmology 1/2024

01.12.2024 | Original Paper

Short-term results of surgical treatment in large idiopathic macular hole cases

verfasst von: S. Doğruya, D. D. Karabacak, M. Altınışık, Y. Delibay, O. C. Kayıkçıoğlu, Ö. R. Kayıkçıoğlu

Erschienen in: International Ophthalmology | Ausgabe 1/2024

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Abstract

Purpose

To evaluate results of the surgical treatment for large stage (Stage 3 and 4) idiopathic macular hole cases with and without ILM flap technique.

Methods

Sixty eyes of 60 patients diagnosed with idiopathic macular hole (MH) were included in the study. Complete ophthalmologic examination and SD-OCT examination were performed in all eyes. MH stages, MH base diameter, height and closest distance were measured quantitatively. Postoperative and 3 months visits were evaluated.

Results

The mean age of the cases was 65.0 ± 8.0 (range 30–84) years, there were 31 (51.7%) female and 29 (48.3%) male patients with a mean follow-up period of 18.1 ± 16.7 (range 3–63) months. The mean best corrected visual acuity recorded at preoperative and third month control visits were 0.89 ± 0.40(preoperative) logMAR, 0.82 ± 0.60(3 month) logMAR (p < 0.05). The mean MH index was 0.48 ± 0.16, the closest hole distance was 517.86 ± 210.89 µm and mean basal diameter of holes was 947.78 ± 361.90 µm and the average height was 448.93 ± 79.80 microns.
There was no statistically significant difference between anatomic results of macular hole surgery with (n = 22) and without (n = 38) flap in terms of hole closure (86.4% vs. 92.1% p > 0.05). In 90% (54 cases) of the cases, closure was observed after the first surgery. Two eyes that failed macular hole surgery were reoperated. In one of these eyes, anatomical success was obtained with macular hole massage and mechanical cytumulation. However, anatomical success could not be achieved in the other eye.

Conclusıon

In the treatment of large macular holes, pars plana vitrectomy, internal limiting membrane peeling with/without flap and gas tamponade demonstrated high anatomical and functional success.
Literatur
1.
Zurück zum Zitat Kang HK, Chang AA, Beaumont PE (2000) The macular hole: report of an Australian surgical series and meta-analysis of the literature. Clin Exp Ophthalmol 28(4):298–308CrossRefPubMed Kang HK, Chang AA, Beaumont PE (2000) The macular hole: report of an Australian surgical series and meta-analysis of the literature. Clin Exp Ophthalmol 28(4):298–308CrossRefPubMed
3.
Zurück zum Zitat Lai MM, Williams GA (2007) Anatomical and visual outcomes of idiopathic macular hole surgery with internal limiting membrane removal using low-concentration indocyanine green. Retina 27(4):477–482CrossRefPubMed Lai MM, Williams GA (2007) Anatomical and visual outcomes of idiopathic macular hole surgery with internal limiting membrane removal using low-concentration indocyanine green. Retina 27(4):477–482CrossRefPubMed
4.
Zurück zum Zitat Margherio RR, Margherio AR, Williams GA, Chow DR, Banach MJ (2000) Effect of perifoveal tissue dissection in the management of acute idiopathic full-thickness macular holes. Arch Ophthalmol 118(4):495–498CrossRefPubMed Margherio RR, Margherio AR, Williams GA, Chow DR, Banach MJ (2000) Effect of perifoveal tissue dissection in the management of acute idiopathic full-thickness macular holes. Arch Ophthalmol 118(4):495–498CrossRefPubMed
5.
Zurück zum Zitat Morgan CM, Schatz H (1986) Involutional macular thinning: a pre-macular hole condition. Ophthalmology 93(2):153–161CrossRefPubMed Morgan CM, Schatz H (1986) Involutional macular thinning: a pre-macular hole condition. Ophthalmology 93(2):153–161CrossRefPubMed
6.
Zurück zum Zitat Reibaldi M, Boscia F, Avitabile T et al (2011) Enhanced depth imaging optical coherence tomography of the choroid in idiopathic macular hole: a cross-sectional prospective study. Am J Ophthalmol 151(1):112-117.e2CrossRefPubMed Reibaldi M, Boscia F, Avitabile T et al (2011) Enhanced depth imaging optical coherence tomography of the choroid in idiopathic macular hole: a cross-sectional prospective study. Am J Ophthalmol 151(1):112-117.e2CrossRefPubMed
7.
Zurück zum Zitat Zeng J, Li J, Liu R et al (2012) Choroidal thickness in both eyes of patients with unilateral idiopathic macular hole. Ophthalmology 119(11):2328–2333CrossRefPubMed Zeng J, Li J, Liu R et al (2012) Choroidal thickness in both eyes of patients with unilateral idiopathic macular hole. Ophthalmology 119(11):2328–2333CrossRefPubMed
8.
Zurück zum Zitat Kim SH, Kim HK, Yang JY, Lee SC, Kim SS (2018) Visual recovery after macular hole surgery and related prognostic factors. Korean J Ophthalmol 32(2):140–146CrossRefPubMedPubMedCentral Kim SH, Kim HK, Yang JY, Lee SC, Kim SS (2018) Visual recovery after macular hole surgery and related prognostic factors. Korean J Ophthalmol 32(2):140–146CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Gass JD (1995) Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol 119(6):752–759CrossRefPubMed Gass JD (1995) Reappraisal of biomicroscopic classification of stages of development of a macular hole. Am J Ophthalmol 119(6):752–759CrossRefPubMed
10.
Zurück zum Zitat Kishi S, Takahashi H (2000) Three-dimensional observations of developing macular holes. Am J Ophthalmol 130(1):65–75CrossRefPubMed Kishi S, Takahashi H (2000) Three-dimensional observations of developing macular holes. Am J Ophthalmol 130(1):65–75CrossRefPubMed
11.
Zurück zum Zitat Samoylov AN, Khaibrakhmanov TR, Fazleeva GA, Samoylova PA (2017) Idiopathic macular hole: history and status quo review. Vestn Oftalmol 133(6):131–137CrossRefPubMed Samoylov AN, Khaibrakhmanov TR, Fazleeva GA, Samoylova PA (2017) Idiopathic macular hole: history and status quo review. Vestn Oftalmol 133(6):131–137CrossRefPubMed
12.
Zurück zum Zitat Kelly NE, Wendel RT (1991) Vitreous surgery for idiopathic macular holes: results of a pilot study. Arch Ophthalmol 109(5):654–659CrossRefPubMed Kelly NE, Wendel RT (1991) Vitreous surgery for idiopathic macular holes: results of a pilot study. Arch Ophthalmol 109(5):654–659CrossRefPubMed
13.
Zurück zum Zitat Wendel RT, Patel AC, Kelly NE et al (1993) Vitreous surgery for macular holes. Ophthalmology 100(11):1671–1676CrossRefPubMed Wendel RT, Patel AC, Kelly NE et al (1993) Vitreous surgery for macular holes. Ophthalmology 100(11):1671–1676CrossRefPubMed
14.
15.
Zurück zum Zitat Kusuhara S, TeraokaEscaño MF, Fujii S et al (2004) Prediction of postoperative visual outcome based on hole configuration by optical coherence tomography in eyes with idiopathic macular holes. Am J Ophthalmol 138(5):709–716CrossRefPubMed Kusuhara S, TeraokaEscaño MF, Fujii S et al (2004) Prediction of postoperative visual outcome based on hole configuration by optical coherence tomography in eyes with idiopathic macular holes. Am J Ophthalmol 138(5):709–716CrossRefPubMed
16.
Zurück zum Zitat Freeman WR, Azen SP, Kim JW et al (1997) Vitrectomy for the treatment of full-thickness stage 3 or 4 macular holes: results of a multicentered randomized clinical trial. The vitrectomy for treatment of macular hole study group. Arch Ophthalmol 115(1):11–21CrossRefPubMed Freeman WR, Azen SP, Kim JW et al (1997) Vitrectomy for the treatment of full-thickness stage 3 or 4 macular holes: results of a multicentered randomized clinical trial. The vitrectomy for treatment of macular hole study group. Arch Ophthalmol 115(1):11–21CrossRefPubMed
17.
Zurück zum Zitat Brooks HL Jr (2000) Macular hole surgery with and without internal limiting membrane peeling. Ophthalmology 107(10):1939–1948CrossRefPubMed Brooks HL Jr (2000) Macular hole surgery with and without internal limiting membrane peeling. Ophthalmology 107(10):1939–1948CrossRefPubMed
18.
Zurück zum Zitat Yu Y, Liang X, Wang Z et al (2020) Internal limiting membrane peeling and air tamponade stage III and stage IV idiopathic macular hole. Retina 40(1):66–74CrossRefPubMed Yu Y, Liang X, Wang Z et al (2020) Internal limiting membrane peeling and air tamponade stage III and stage IV idiopathic macular hole. Retina 40(1):66–74CrossRefPubMed
19.
Zurück zum Zitat Ip MS, Baker BJ, Duker JS et al (2002) Anatomical outcomes of surgery for idiopathic macular hole as determined by optical coherence tomography. Arch Ophthalmol 120(1):29–35CrossRefPubMed Ip MS, Baker BJ, Duker JS et al (2002) Anatomical outcomes of surgery for idiopathic macular hole as determined by optical coherence tomography. Arch Ophthalmol 120(1):29–35CrossRefPubMed
20.
Zurück zum Zitat Haritoglou C, Neubauer AS, Reiniger IW et al (2007) Long-term functional outcome of macular hole surgery correlated to optical coherence tomography measurements. Clin Exp Ophthalmol 35(3):208–213CrossRefPubMed Haritoglou C, Neubauer AS, Reiniger IW et al (2007) Long-term functional outcome of macular hole surgery correlated to optical coherence tomography measurements. Clin Exp Ophthalmol 35(3):208–213CrossRefPubMed
21.
Zurück zum Zitat Ruiz-Moreno JM, Staicu C, Piñero DP et al (2008) Optical coherence tomography predictive factors for macular hole surgery outcome. Br J Ophthalmol 92(5):640–644CrossRefPubMed Ruiz-Moreno JM, Staicu C, Piñero DP et al (2008) Optical coherence tomography predictive factors for macular hole surgery outcome. Br J Ophthalmol 92(5):640–644CrossRefPubMed
22.
Zurück zum Zitat Wakely L, Rahman R, Stephenson J (2012) A comparison of several methods of macular hole measurement using optical coherence tomography, and their value in predicting anatomical and visual outcomes. Br J Ophthalmol 96(7):1003–1007CrossRefPubMed Wakely L, Rahman R, Stephenson J (2012) A comparison of several methods of macular hole measurement using optical coherence tomography, and their value in predicting anatomical and visual outcomes. Br J Ophthalmol 96(7):1003–1007CrossRefPubMed
23.
Zurück zum Zitat Liu P, Sun Y, Dong C et al (2016) A new method to predict anatomical outcome after idiopathic macular hole surgery. Graefes Arch Clin Exp Ophthalmol 254(4):683–688CrossRefPubMed Liu P, Sun Y, Dong C et al (2016) A new method to predict anatomical outcome after idiopathic macular hole surgery. Graefes Arch Clin Exp Ophthalmol 254(4):683–688CrossRefPubMed
24.
Zurück zum Zitat Thompson JT, Smiddy WE, Glaser BM, Sjaarda RN, Flynn HW Jr (1996) Intraocular tamponade duration and success of macular hole surgery. Retina 16(5):373–382CrossRefPubMed Thompson JT, Smiddy WE, Glaser BM, Sjaarda RN, Flynn HW Jr (1996) Intraocular tamponade duration and success of macular hole surgery. Retina 16(5):373–382CrossRefPubMed
25.
Zurück zum Zitat Tadayoni R, Gaudric A, Haouchine B, Massin P (2006) Relationship between macular holesize and the potential benefit of internal limiting membrane peeling. Br J Ophthalmol 90(10):1239–1241CrossRefPubMedPubMedCentral Tadayoni R, Gaudric A, Haouchine B, Massin P (2006) Relationship between macular holesize and the potential benefit of internal limiting membrane peeling. Br J Ophthalmol 90(10):1239–1241CrossRefPubMedPubMedCentral
26.
Zurück zum Zitat Christensen UC (2009) Value of internal limiting membrane peeling in surgery for idiopathic macular hole and the correlation between function and retinal morphology. Acta Ophthalmol 87(Thesis 2):1–23CrossRefPubMed Christensen UC (2009) Value of internal limiting membrane peeling in surgery for idiopathic macular hole and the correlation between function and retinal morphology. Acta Ophthalmol 87(Thesis 2):1–23CrossRefPubMed
27.
Zurück zum Zitat Al-Abdulla NA, Thompson JT, Sjaarda RN (2004) Results of macular hole surgery with and without epiretinal dissection or internal limiting membrane removal. Ophthalmology 111(1):142–149CrossRefPubMed Al-Abdulla NA, Thompson JT, Sjaarda RN (2004) Results of macular hole surgery with and without epiretinal dissection or internal limiting membrane removal. Ophthalmology 111(1):142–149CrossRefPubMed
28.
Zurück zum Zitat Bainbridge J, Herbert E, Gregor Z (2008) Macular holes: vitreoretinal relationships and surgical approaches. Eye (Lond) 22(10):1301–1309CrossRefPubMed Bainbridge J, Herbert E, Gregor Z (2008) Macular holes: vitreoretinal relationships and surgical approaches. Eye (Lond) 22(10):1301–1309CrossRefPubMed
29.
Zurück zum Zitat Christensen UC, Krøyer K, Sander B, Larsen M, la Cour M (2009) Prognostic significance of delayed structural recovery after macular hole surgery. Ophthalmology 116(12):2430–2436CrossRefPubMed Christensen UC, Krøyer K, Sander B, Larsen M, la Cour M (2009) Prognostic significance of delayed structural recovery after macular hole surgery. Ophthalmology 116(12):2430–2436CrossRefPubMed
30.
Zurück zum Zitat Chen WC, Wang Y, Li XX (2012) Morphologic and functional evaluation before and after successful macular hole surgery using spectral-domain optical coherence tomography combined with microperimetry. Retina 32(9):1733–1742CrossRefPubMed Chen WC, Wang Y, Li XX (2012) Morphologic and functional evaluation before and after successful macular hole surgery using spectral-domain optical coherence tomography combined with microperimetry. Retina 32(9):1733–1742CrossRefPubMed
31.
Zurück zum Zitat Itoh Y, Inoue M, Rii T, Hiraoka T, Hirakata A (2012) Correlation between length of foveal cone outer segment tips line defect and visual acuity after macular hole closure. Ophthalmology 119(7):1438–1446CrossRefPubMed Itoh Y, Inoue M, Rii T, Hiraoka T, Hirakata A (2012) Correlation between length of foveal cone outer segment tips line defect and visual acuity after macular hole closure. Ophthalmology 119(7):1438–1446CrossRefPubMed
32.
Zurück zum Zitat Leonard RE 2nd, Smiddy WE, Flynn HW Jr, Feuer W (1997) Long-term visual outcomes in patients with successful macular hole surgery. Ophthalmology 104(10):1648–1652CrossRefPubMed Leonard RE 2nd, Smiddy WE, Flynn HW Jr, Feuer W (1997) Long-term visual outcomes in patients with successful macular hole surgery. Ophthalmology 104(10):1648–1652CrossRefPubMed
33.
Zurück zum Zitat Velez-Montoya R, Ramirez-Estudillo JA, Sjoholm-Gomez de Liano C et al (2018) Inverted ILM flap, free ILM flap and conventional ILM peeling for large macular holes. Int J Retin Vitr 4:8CrossRef Velez-Montoya R, Ramirez-Estudillo JA, Sjoholm-Gomez de Liano C et al (2018) Inverted ILM flap, free ILM flap and conventional ILM peeling for large macular holes. Int J Retin Vitr 4:8CrossRef
34.
Zurück zum Zitat Jaycock PD, Bunce C, Xing W et al (2005) Outcomes of macular hole surgery: implications for surgical management and clinical governance. Eye (Lond) 19(8):879–884CrossRefPubMed Jaycock PD, Bunce C, Xing W et al (2005) Outcomes of macular hole surgery: implications for surgical management and clinical governance. Eye (Lond) 19(8):879–884CrossRefPubMed
36.
Zurück zum Zitat Ferreira MA, Maia A, Machado AJ et al (2021) Human amniotic membrane for the treatment of large and refractory macular holes: a retrospective, multicentric, interventional study. Int J Retina Vitr 7(1):38CrossRef Ferreira MA, Maia A, Machado AJ et al (2021) Human amniotic membrane for the treatment of large and refractory macular holes: a retrospective, multicentric, interventional study. Int J Retina Vitr 7(1):38CrossRef
Metadaten
Titel
Short-term results of surgical treatment in large idiopathic macular hole cases
verfasst von
S. Doğruya
D. D. Karabacak
M. Altınışık
Y. Delibay
O. C. Kayıkçıoğlu
Ö. R. Kayıkçıoğlu
Publikationsdatum
01.12.2024
Verlag
Springer Netherlands
Erschienen in
International Ophthalmology / Ausgabe 1/2024
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI
https://doi.org/10.1007/s10792-024-03121-w

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