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Experimental Brain Research

Erschienen in:

01.09.2005 | Research Article

Smooth-pursuit eye movement and directional motion-contrast sensitivity in schizophrenia

verfasst von: Walter L. Slaghuis, Alison C. Bowling, Rebecca V. French

Erschienen in: Experimental Brain Research | Ausgabe 1/2005

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Abstract

Although the occurrence of visual processing and eye-movement disorders in schizophrenia have been widely recognized, their relationship with the symptoms of schizophrenia is less well understood. In two experiments the relationship between directional-motion processing and smooth-pursuit eye movement was investigated in normal observers and in groups with positive and negative symptoms in schizophrenia. The first experiment measured linear smooth-pursuit eye movement at six target velocities from 5.0 to 30.0° s⁻¹ and the second experiment measured directional motion-contrast sensitivity at three spatial (1.0, 4.0 and 8.0 c/deg) and five temporal (0.75, 3.0, 6.0, 12.0 and 18.0 Hz) frequencies in the same groups of observers. No significant differences were found between the control and positive-symptom group in directional motion-contrast sensitivity and smooth-pursuit eye movements. In comparison, a relationship was found between a significant reduction in directional motion-contrast sensitivity and significantly reduced smooth-pursuit eye movement in the negative-symptom group and serves to further cleave the distinction between positive and negative symptoms in schizophrenia. The relationship between visual motion processing and pursuit eye movement in the negative-symptom group was explained by a disorder in directional motion processing that fails to fully engage the pursuit eye movement system and reduces smooth pursuit eye-velocity gain.

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Titel: Smooth-pursuit eye movement and directional motion-contrast sensitivity in schizophrenia
verfasst von: Walter L. Slaghuis
Alison C. Bowling
Rebecca V. French
Publikationsdatum: 01.09.2005
Verlag: Springer-Verlag
Erschienen in: Experimental Brain Research / Ausgabe 1/2005
Print ISSN: 0014-4819
Elektronische ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-005-2347-1

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