Background
Methods
Inclusion criteria
Definition of the intervention
Assessment of effects
Objectives | Indicators |
---|---|
Giving up smoking | % of patients who gave up smoking % of patients who continued to smoke but reduced tobacco consumption |
Having BMI < 25 | % of patients with BMI ≥ 25 who reduced it by at least 10% % of patients with BMI ≥ 25 who reduced it by at least 5% % of patients who went from BMI ≥ 25 to BMI < 25 % of patients with BMI ≥ 30 who reduced it by at least 10% % of patients with BMI ≥ 30 who reduced it by at least 5% % of patients who went from BMI ≥ 30 to BMI < 30 |
Doing regular exercise | % of patients who do physical exercise at least three times a week for at least 20/30 minutes % of patients who do physical exercise at least five times a week for at least 20/30 minutes (only this exercise indicator in diabetic patients) |
Controlling lipid levels | % of patients with total cholesterol < 175 mg/dl % of patients with LDL cholesterol < 100 mg/dl (< 70 mg/dl in diabetics) % of patients with LDL cholesterol < 70 mg/dl % of patients with HDL cholesterol ≥ 40 mg/dl % of patients with triglycerides < 150 mg/dl |
Controlling hypertension | % of patients with hypertension who have had their blood pressure controlled since discharge % of patients with blood pressure < 135/80 mmHg (< 130/80 mmHg in diabetics) |
Taking prescribed medication | % of patients taking AAS (6 months) when prescribed at discharge % of patients taking Clopidogrel (6 months) when prescribed at discharge % of patients taking beta blockers (6 months) when prescribed at discharge % of patients taking ACE-inhibitors (6 months) when prescribed at discharge % of patients taking angiotensin receptor blocking agent Type II (ARA II) (6 months) when prescribed at discharge % of patients taking statins (6 months) when prescribed at discharge |
Plan of analysis
Subgroup analysis
Calculation of Sample Size
Results
Intervention (n = 867) | Control (n = 890) | p-value | |
---|---|---|---|
Males | 77.7 | 75.6 | 0.301 |
Age (years old) (mean ± sd) | 62.1 ± 11.6 | 63.6 ± 11.4 | 0.007 |
Present diagnosis AMI | 65.9 | 64.6 | 0.304 |
Family history of ischemic cardiomyopathy | 18.7 | 17.9 | 0.657 |
Certain previous diagnosis of ischemic cardiomyopathy | 31.5 | 29.1 | 0.276 |
Personal history: | |||
Stroke | 4.8 | 6.4 | 0.156 |
Peripheral arteriopathy | 8.8 | 9.3 | 0.683 |
Renal failure | 5.3 | 5.8 | 0.624 |
Arterial hypertension | 58.9 | 60.1 | 0.616 |
Hypercholesterolemia | 51.4 | 50.7 | 0.748 |
Diabetes | 25.3 | 29.6 | 0.044 |
Obesity | 31.3 | 34.2 | 0.195 |
Smokers | 33.3 | 26.1 | 0.001 |
BMI (kg/m2) (average ± sd) | 28.2 ± 4.2 | 28.3 ± 4.3 | 0.627 |
BMI ≥ 30 kg/m2
| 29.6 | 30.4 | 0.932 |
Abdominal perimeter (men/women) ≥ 102/88 cm | 47.8 | 51.8 | 0.172 |
Abdominal perimeter (men/women) ≥ 94/80 cm | 74.0 | 74.3 | 0.929 |
Objectives (nI/nC) | Intervention (n = 762) | Control (n = 748) | Adjustedγ
Odds ratio | Adjusted OR 95% CI | p-value |
---|---|---|---|---|---|
Given up smoking (253/200) | 76.3 | 71.0 | 1.25 | 0.81-1.94 | 0.309 |
BMI ≥ 25 kg/m2 (567/547) | |||||
< 25 kg/m2
| 9.9 | 7.8 | 1.21 | 0.79-1.86 | 0. 373 |
⇓ BMI ≥ 10% | 7.4 | 6.8 | 1.15 | 0.72-1.84 | 0.564 |
⇓ BMI ≥ 5% | 25.0 | 19.7 | 1.31 | 0.98-1.76 | 0.068 |
BMI ≥ 30 kg/m2 (212/209) | |||||
< 30 kg/m2
| 25.9 | 24.9 | 1.04 | 0.66-1.63 | 0.860 |
⇓ BMI ≥ 10% | 11.3 | 10.5 | 1.15 | 0.61-2.17 | 0.666 |
⇓ BMI ≥ 5% | 32.1 | 27.8 | 1.26 | 0.82-1.93 | 0.300 |
Changes in BMI (average) (kg/m2)* | - 0.5 | - 0.2 | 0.35* | 0.16-0.55* | < 0.001 |
Changes in abdominal perimeter (average) (cm)* | - 1.6 | - 0.6 | 1.03* | 0.00-2.06* | 0.05 |
Exercise 5 times/week | 29.4 | 23.4 | 1.29 | 1.02-1.64 | 0.033 |
Exercise 3 times/week | 48.4 | 41.0 | 1.29 | 1.05-1.59 | 0.017 |
Cholesterol < 175 md/dl | 64.7 | 56.5 | 1.46 | 1.17-1.81 | 0.001 |
LDL < 100 mg/dl (70 in diabetic patients) | 47.9 | 44.8 | 1.09 | 0.87-1.35 | 0.449 |
BP < 135/80 mmHg (130/80 in diabetic patients) | 46.7 | 42.4 | 1.14 | 0.91-1.41 | 0.253 |
Taking of medication (percentage who take it on final visit, out of total given medication on discharge from hospital) | |||||
Aspirin (712/698) | 97.5 | 96.0 | 1.54 | 0.84-2.83 | 0.161 |
Clopidogrel (571/533) | 72.9 | 74.3 | 0.91 | 0.69-1.20 | 0.499 |
Beta-blockers (621/590) | 94.4 | 94.6 | 0.93 | 0.56-1.54 | 0.769 |
ACE-inhibitors (400/387) | 86.8 | 84.0 | 1.31 | 0.87-1.98 | 0.192 |
Angiotensin receptor blocking agent Type II (ARA II) (86/97) | 84.9 | 86.6 | 0.83 | 0.35-1.95 | 0.664 |
Statins (677/635) | 98.1 | 95.9 | 0.83 | 0.35-1.95 | 0.029 |