Towards dysfunctional connectome development in depressed adolescents

Zurück zum Zitat Thapar A, Eyre O, Patel V, Brent D (2022) Depression in young people. Lancet 400:617–631CrossRefPubMed Thapar A, Eyre O, Patel V, Brent D (2022) Depression in young people. Lancet 400:617–631CrossRefPubMed

Zurück zum Zitat Zheng R, Chen Y, Jiang Y, Zhou B, Han S, Wei Y, Wang C, Cheng J (2022) Abnormal voxel-wise whole-brain functional connectivity in first-episode, drug-naive adolescents with major depression disorder. Eur Child Adolesc Psychiatry. https://doi.org/10.1007/s00787-022-01959-yCrossRefPubMed Zheng R, Chen Y, Jiang Y, Zhou B, Han S, Wei Y, Wang C, Cheng J (2022) Abnormal voxel-wise whole-brain functional connectivity in first-episode, drug-naive adolescents with major depression disorder. Eur Child Adolesc Psychiatry. https://​doi.​org/​10.​1007/​s00787-022-01959-yCrossRefPubMed

Zurück zum Zitat Zhou Z, Gao Y, Feng R, Zhuo L, Bao W, Liang K, Qiu H, Cao L, Tang M, Li H, Zhang L, Huang G, Huang X (2022) Aberrant intrinsic hippocampal and orbitofrontal connectivity in drug-naive adolescent patients with major depressive disorder. Eur Child Adolesc Psychiatry. https://doi.org/10.1007/s00787-022-02086-4CrossRefPubMed Zhou Z, Gao Y, Feng R, Zhuo L, Bao W, Liang K, Qiu H, Cao L, Tang M, Li H, Zhang L, Huang G, Huang X (2022) Aberrant intrinsic hippocampal and orbitofrontal connectivity in drug-naive adolescent patients with major depressive disorder. Eur Child Adolesc Psychiatry. https://​doi.​org/​10.​1007/​s00787-022-02086-4CrossRefPubMed

Zurück zum Zitat Schmaal L, Veltman DJ, van Erp TG, Samann PG, Frodl T, Jahanshad N, Loehrer E, Tiemeier H, Hofman A, Niessen WJ, Vernooij MW, Ikram MA, Wittfeld K, Grabe HJ, Block A, Hegenscheid K, Volzke H, Hoehn D, Czisch M, Lagopoulos J, Hatton SN, Hickie IB, Goya-Maldonado R, Kramer B, Gruber O, Couvy-Duchesne B, Renteria ME, Strike LT, Mills NT, de Zubicaray GI, McMahon KL, Medland SE, Martin NG, Gillespie NA, Wright MJ, Hall GB, MacQueen GM, Frey EM, Carballedo A, van Velzen LS, van Tol MJ, van der Wee NJ, Veer IM, Walter H, Schnell K, Schramm E, Normann C, Schoepf D, Konrad C, Zurowski B, Nickson T, McIntosh AM, Papmeyer M, Whalley HC, Sussmann JE, Godlewska BR, Cowen PJ, Fischer FH, Rose M, Penninx BW, Thompson PM, Hibar DP (2016) Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group. Mol Psychiatry 21:806–812CrossRefPubMed Schmaal L, Veltman DJ, van Erp TG, Samann PG, Frodl T, Jahanshad N, Loehrer E, Tiemeier H, Hofman A, Niessen WJ, Vernooij MW, Ikram MA, Wittfeld K, Grabe HJ, Block A, Hegenscheid K, Volzke H, Hoehn D, Czisch M, Lagopoulos J, Hatton SN, Hickie IB, Goya-Maldonado R, Kramer B, Gruber O, Couvy-Duchesne B, Renteria ME, Strike LT, Mills NT, de Zubicaray GI, McMahon KL, Medland SE, Martin NG, Gillespie NA, Wright MJ, Hall GB, MacQueen GM, Frey EM, Carballedo A, van Velzen LS, van Tol MJ, van der Wee NJ, Veer IM, Walter H, Schnell K, Schramm E, Normann C, Schoepf D, Konrad C, Zurowski B, Nickson T, McIntosh AM, Papmeyer M, Whalley HC, Sussmann JE, Godlewska BR, Cowen PJ, Fischer FH, Rose M, Penninx BW, Thompson PM, Hibar DP (2016) Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group. Mol Psychiatry 21:806–812CrossRefPubMed

Zurück zum Zitat Schmaal L, Hibar DP, Samann PG, Hall GB, Baune BT, Jahanshad N, Cheung JW, van Erp TGM, Bos D, Ikram MA, Vernooij MW, Niessen WJ, Tiemeier H, Hofman A, Wittfeld K, Grabe HJ, Janowitz D, Bulow R, Selonke M, Volzke H, Grotegerd D, Dannlowski U, Arolt V, Opel N, Heindel W, Kugel H, Hoehn D, Czisch M, Couvy-Duchesne B, Renteria ME, Strike LT, Wright MJ, Mills NT, de Zubicaray GI, McMahon KL, Medland SE, Martin NG, Gillespie NA, Goya-Maldonado R, Gruber O, Kramer B, Hatton SN, Lagopoulos J, Hickie IB, Frodl T, Carballedo A, Frey EM, van Velzen LS, Penninx B, van Tol MJ, van der Wee NJ, Davey CG, Harrison BJ, Mwangi B, Cao B, Soares JC, Veer IM, Walter H, Schoepf D, Zurowski B, Konrad C, Schramm E, Normann C, Schnell K, Sacchet MD, Gotlib IH, MacQueen GM, Godlewska BR, Nickson T, McIntosh AM, Papmeyer M, Whalley HC, Hall J, Sussmann JE, Li M, Walter M, Aftanas L, Brack I, Bokhan NA, Thompson PM, Veltman DJ (2017) Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Mol Psychiatry 22:900–909CrossRefPubMed Schmaal L, Hibar DP, Samann PG, Hall GB, Baune BT, Jahanshad N, Cheung JW, van Erp TGM, Bos D, Ikram MA, Vernooij MW, Niessen WJ, Tiemeier H, Hofman A, Wittfeld K, Grabe HJ, Janowitz D, Bulow R, Selonke M, Volzke H, Grotegerd D, Dannlowski U, Arolt V, Opel N, Heindel W, Kugel H, Hoehn D, Czisch M, Couvy-Duchesne B, Renteria ME, Strike LT, Wright MJ, Mills NT, de Zubicaray GI, McMahon KL, Medland SE, Martin NG, Gillespie NA, Goya-Maldonado R, Gruber O, Kramer B, Hatton SN, Lagopoulos J, Hickie IB, Frodl T, Carballedo A, Frey EM, van Velzen LS, Penninx B, van Tol MJ, van der Wee NJ, Davey CG, Harrison BJ, Mwangi B, Cao B, Soares JC, Veer IM, Walter H, Schoepf D, Zurowski B, Konrad C, Schramm E, Normann C, Schnell K, Sacchet MD, Gotlib IH, MacQueen GM, Godlewska BR, Nickson T, McIntosh AM, Papmeyer M, Whalley HC, Hall J, Sussmann JE, Li M, Walter M, Aftanas L, Brack I, Bokhan NA, Thompson PM, Veltman DJ (2017) Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group. Mol Psychiatry 22:900–909CrossRefPubMed

Zurück zum Zitat Xia M, Liu J, Mechelli A, Sun X, Ma Q, Wang X, Wei D, Chen Y, Liu B, Huang CC, Zheng Y, Wu Y, Chen T, Cheng Y, Xu X, Gong Q, Si T, Qiu S, Lin CP, Cheng J, Tang Y, Wang F, Qiu J, Xie P, Li L, Group D-MW, He Y (2022) Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes. Mol Psychiatry 27:1384–1393CrossRefPubMed Xia M, Liu J, Mechelli A, Sun X, Ma Q, Wang X, Wei D, Chen Y, Liu B, Huang CC, Zheng Y, Wu Y, Chen T, Cheng Y, Xu X, Gong Q, Si T, Qiu S, Lin CP, Cheng J, Tang Y, Wang F, Qiu J, Xie P, Li L, Group D-MW, He Y (2022) Connectome gradient dysfunction in major depression and its association with gene expression profiles and treatment outcomes. Mol Psychiatry 27:1384–1393CrossRefPubMed

Zurück zum Zitat Jin C, Gao C, Chen C, Ma S, Netra R, Wang Y, Zhang M, Li D (2011) A preliminary study of the dysregulation of the resting networks in first-episode medication-naive adolescent depression. Neurosci Lett 503:105–109CrossRefPubMed Jin C, Gao C, Chen C, Ma S, Netra R, Wang Y, Zhang M, Li D (2011) A preliminary study of the dysregulation of the resting networks in first-episode medication-naive adolescent depression. Neurosci Lett 503:105–109CrossRefPubMed

Zurück zum Zitat Cash RFH, Müller VI, Fitzgerald PB, Eickhoff SB, Zalesky A (2023) Altered brain activity in unipolar depression unveiled using connectomics. Nature Mental Health 1:174–185CrossRef Cash RFH, Müller VI, Fitzgerald PB, Eickhoff SB, Zalesky A (2023) Altered brain activity in unipolar depression unveiled using connectomics. Nature Mental Health 1:174–185CrossRef

Zurück zum Zitat Li X, Yu R, Huang Q, Chen X, Ai M, Zhou Y, Dai L, Qin X, Kuang L (2021) Alteration of whole brain ALFF/fALFF and degree centrality in adolescents with depression and suicidal ideation after electroconvulsive therapy: a Resting-State fMRI Study. Front Hum Neurosci 15:762343CrossRefPubMedPubMedCentral Li X, Yu R, Huang Q, Chen X, Ai M, Zhou Y, Dai L, Qin X, Kuang L (2021) Alteration of whole brain ALFF/fALFF and degree centrality in adolescents with depression and suicidal ideation after electroconvulsive therapy: a Resting-State fMRI Study. Front Hum Neurosci 15:762343CrossRefPubMedPubMedCentral

Zurück zum Zitat Cullen KR, Klimes-Dougan B, Vu DP, Westlund Schreiner M, Mueller BA, Eberly LE, Camchong J, Westervelt A, Lim KO (2016) Neural correlates of antidepressant treatment response in adolescents with major depressive disorder. J Child Adolesc Psychopharmacol 26:705–712CrossRefPubMedPubMedCentral Cullen KR, Klimes-Dougan B, Vu DP, Westlund Schreiner M, Mueller BA, Eberly LE, Camchong J, Westervelt A, Lim KO (2016) Neural correlates of antidepressant treatment response in adolescents with major depressive disorder. J Child Adolesc Psychopharmacol 26:705–712CrossRefPubMedPubMedCentral