Skip to main content
Erschienen in: Clinical Research in Cardiology 12/2012

01.12.2012 | Original Paper

Transcatheter Edwards Sapien XT valve in valve implantation in degenerated aortic bioprostheses via transfemoral access

verfasst von: Martin Greif, Philipp Lange, Helmut Mair, Christoph Becker, Christoph Schmitz, Gerhard Steinbeck, Christian Kupatt

Erschienen in: Clinical Research in Cardiology | Ausgabe 12/2012

Einloggen, um Zugang zu erhalten

Abstract

Objectives

Surgical treatment of degenerated aortic bioprostheses is associated with an increased risk of morbidity and mortality, especially in elderly patients with significant co-morbidities. Therefore, transcatheter aortic valve implantation (TAVI) performed as valve in valve technique appears as an attractive alternative treatment option. We report of a case series of seven patients with dysfunctional bioprosthetic aortic heart valves who have been treated with TAVI via transfemoral access.

Methods and results

Valve in valve implantation using the Edwards Sapien XT bioprostheses (Edwards Lifesciences LLC, Irvine, CA, USA) was performed in eight patients (3 men, 5 women, mean age 85.3 ± 6.1 years) with a high operative risk (logistic euroSCORE 27.2 ± 7.3). Six patients underwent TAVI because of high grade stenosis of the aortic bioprostheses, whereas two patients presented with high grade regurgitation. All patients suffered at least from NYHA class III dyspnea during admission. TAVI was successfully performed via transfemoral access under local anesthesia with mild analgesic medication in all cases. Mild aortic regurgitation occurred in three patients while no permanent pacemaker implantation was required. Major cardiac events or cerebrovascular events did not occur. One aneurysm spurium, with the need of one blood transfusion, occurred. All patients improved at least one NYHA class within 30 days.

Conclusion

TAVI for degenerated aortic bioprostheses, using the Edwards Sapien XT valve via transfemoral access is a feasible option for patients at high surgical risk.
Literatur
1.
Zurück zum Zitat Hammermeister K, Sethi GK, Henderson WG, Grover FL, Oprian C, Rahimtoola SH (2000) Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve: final report of the Veterans Affairs randomized trial. J Am Coll Cardiol 36(4):1152–1158PubMedCrossRef Hammermeister K, Sethi GK, Henderson WG, Grover FL, Oprian C, Rahimtoola SH (2000) Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve: final report of the Veterans Affairs randomized trial. J Am Coll Cardiol 36(4):1152–1158PubMedCrossRef
2.
Zurück zum Zitat Khan SS, Trento A, DeRobertis M, Kass RM, Sandhu M, Czer LS, Blanche C, Raissi S, Fontana GP, Cheng W, Chaux A, Matloff JM (2001) Twenty-year comparison of tissue and mechanical valve replacement. J Thorac Cardiovasc Surg 122(2):257–269PubMedCrossRef Khan SS, Trento A, DeRobertis M, Kass RM, Sandhu M, Czer LS, Blanche C, Raissi S, Fontana GP, Cheng W, Chaux A, Matloff JM (2001) Twenty-year comparison of tissue and mechanical valve replacement. J Thorac Cardiovasc Surg 122(2):257–269PubMedCrossRef
3.
Zurück zum Zitat Kassaï B, Gueyffier F, Cucherat M, Boissel JP (2000) Comparison of bioprosthesis and mechanical valves, a meta-analysis of randomised clinical trials. Cardiovasc Surg 8(6):477–483PubMedCrossRef Kassaï B, Gueyffier F, Cucherat M, Boissel JP (2000) Comparison of bioprosthesis and mechanical valves, a meta-analysis of randomised clinical trials. Cardiovasc Surg 8(6):477–483PubMedCrossRef
4.
Zurück zum Zitat Jones JM, O’kane H, Gladstone DJ, Sarsam MA, Campalani G, MacGowan SW, Cleland J, Cran GW (2001) Repeat heart valve surgery: risk factors for operative mortality. J Thorac Cardiovasc Surg 122(5):913–918PubMedCrossRef Jones JM, O’kane H, Gladstone DJ, Sarsam MA, Campalani G, MacGowan SW, Cleland J, Cran GW (2001) Repeat heart valve surgery: risk factors for operative mortality. J Thorac Cardiovasc Surg 122(5):913–918PubMedCrossRef
5.
Zurück zum Zitat Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, Wang D, Pocock S; PARTNER Trial Investigators (2010) Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 363(17):1597–1607 (Epub 2010 Sep 22) Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Brown DL, Block PC, Guyton RA, Pichard AD, Bavaria JE, Herrmann HC, Douglas PS, Petersen JL, Akin JJ, Anderson WN, Wang D, Pocock S; PARTNER Trial Investigators (2010) Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery. N Engl J Med 363(17):1597–1607 (Epub 2010 Sep 22)
6.
Zurück zum Zitat Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ; PARTNER Trial Investigators (2011) Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med 364(23):2187–2198 (Epub 2011 Jun 5) Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, Tuzcu EM, Webb JG, Fontana GP, Makkar RR, Williams M, Dewey T, Kapadia S, Babaliaros V, Thourani VH, Corso P, Pichard AD, Bavaria JE, Herrmann HC, Akin JJ, Anderson WN, Wang D, Pocock SJ; PARTNER Trial Investigators (2011) Transcatheter versus surgical aortic-valve replacement in high-risk patients. N Engl J Med 364(23):2187–2198 (Epub 2011 Jun 5)
7.
Zurück zum Zitat Figulla L, Neumann A, Figulla HR, Kahlert P, Erbel R, Neumann T (2011) Transcatheter aortic valve implantation: evidence on safety and efficacy compared with medical therapy. A systematic review of current literature. Clin Res Cardiol 100(4):265–276PubMedCrossRef Figulla L, Neumann A, Figulla HR, Kahlert P, Erbel R, Neumann T (2011) Transcatheter aortic valve implantation: evidence on safety and efficacy compared with medical therapy. A systematic review of current literature. Clin Res Cardiol 100(4):265–276PubMedCrossRef
8.
Zurück zum Zitat Gotzmann M, Mügge A, Bojara W (2010) Transcatheter aortic valve implantation for treatment of patients with degenerated aortic bioprostheses–valve-in-valve technique. Catheter Cardiovasc Interv 76(7):1000–1006. doi:10.1002/ccd.22738 (Epub 2010 Nov 17)PubMedCrossRef Gotzmann M, Mügge A, Bojara W (2010) Transcatheter aortic valve implantation for treatment of patients with degenerated aortic bioprostheses–valve-in-valve technique. Catheter Cardiovasc Interv 76(7):1000–1006. doi:10.​1002/​ccd.​22738 (Epub 2010 Nov 17)PubMedCrossRef
9.
Zurück zum Zitat Khawaja MZ, Haworth P, Ghuran A, Lee L, de Belder A, Hutchinson N, Trivedi U, Laborde JC, Hildick-Smith D (2010) Transcatheter aortic valve implantation for stenosed and regurgitant aortic valve bioprostheses CoreValve for failed bioprosthetic aortic valve replacements. J Am Coll Cardiol 55(2):97–101PubMedCrossRef Khawaja MZ, Haworth P, Ghuran A, Lee L, de Belder A, Hutchinson N, Trivedi U, Laborde JC, Hildick-Smith D (2010) Transcatheter aortic valve implantation for stenosed and regurgitant aortic valve bioprostheses CoreValve for failed bioprosthetic aortic valve replacements. J Am Coll Cardiol 55(2):97–101PubMedCrossRef
10.
Zurück zum Zitat Wenaweser P, Buellesfeld L, Gerckens U, Grube E (2007) Percutaneous aortic valve replacement for severe aortic regurgitation in degenerated bioprosthesis: the first valve in valve procedure using the Corevalve Revalving system. Catheter Cardiovasc Interv 70(5):760–764PubMedCrossRef Wenaweser P, Buellesfeld L, Gerckens U, Grube E (2007) Percutaneous aortic valve replacement for severe aortic regurgitation in degenerated bioprosthesis: the first valve in valve procedure using the Corevalve Revalving system. Catheter Cardiovasc Interv 70(5):760–764PubMedCrossRef
11.
Zurück zum Zitat Bedogni F, Laudisa ML, Pizzocri S, Tamburino C, Ussia GP, Petronio AS, Napodano M, Ramondo A, Presbitero P, Ettori F, Santoro G, Klugman S, De Marco F, Brambilla N, Testa L (2011) Transcatheter valve-in-valve implantation using Corevalve Revalving System for failed surgical aortic bioprostheses. JACC Cardiovasc Interv 4(11):1228–1234PubMedCrossRef Bedogni F, Laudisa ML, Pizzocri S, Tamburino C, Ussia GP, Petronio AS, Napodano M, Ramondo A, Presbitero P, Ettori F, Santoro G, Klugman S, De Marco F, Brambilla N, Testa L (2011) Transcatheter valve-in-valve implantation using Corevalve Revalving System for failed surgical aortic bioprostheses. JACC Cardiovasc Interv 4(11):1228–1234PubMedCrossRef
12.
Zurück zum Zitat Webb JG, Wood DA, Ye J, Gurvitch R, Masson JB, Rodés-Cabau J, Osten M, Horlick E, Wendler O, Dumont E, Carere RG, Wijesinghe N, Nietlispach F, Johnson M, Thompson CR, Moss R, Leipsic J, Munt B, Lichtenstein SV, Cheung A (2010) Transcatheter valve-in-valve implantation for failed bioprosthetic heart valves. Circulation 121(16):1848–1857 (Epub 2010 Apr 12) Webb JG, Wood DA, Ye J, Gurvitch R, Masson JB, Rodés-Cabau J, Osten M, Horlick E, Wendler O, Dumont E, Carere RG, Wijesinghe N, Nietlispach F, Johnson M, Thompson CR, Moss R, Leipsic J, Munt B, Lichtenstein SV, Cheung A (2010) Transcatheter valve-in-valve implantation for failed bioprosthetic heart valves. Circulation 121(16):1848–1857 (Epub 2010 Apr 12)
13.
Zurück zum Zitat Latib A, Ielasi A, Montorfano M, Maisano F, Chieffo A, Cioni M, Mussardo M, Bertoldi L, Shannon J, Sacco F, Covello RD, Figini F, Godino C, Grimaldi A, Spagnolo P, Alfieri O, Colombo A (2012) Transcatheter valve-in-valve implantation with the Edwards SAPIEN in patients with bioprosthetic heart valve failure: the Milan experience. EuroIntervention. pii: 20120109-00 (Epub ahead of print) Latib A, Ielasi A, Montorfano M, Maisano F, Chieffo A, Cioni M, Mussardo M, Bertoldi L, Shannon J, Sacco F, Covello RD, Figini F, Godino C, Grimaldi A, Spagnolo P, Alfieri O, Colombo A (2012) Transcatheter valve-in-valve implantation with the Edwards SAPIEN in patients with bioprosthetic heart valve failure: the Milan experience. EuroIntervention. pii: 20120109-00 (Epub ahead of print)
14.
Zurück zum Zitat Azadani AN, Tseng EE (2011) Transcatheter heart valves for failing bioprostheses: state-of-the-art review of valve-in-valve implantation. Circ Cardiovasc Interv 4(6):621–628PubMedCrossRef Azadani AN, Tseng EE (2011) Transcatheter heart valves for failing bioprostheses: state-of-the-art review of valve-in-valve implantation. Circ Cardiovasc Interv 4(6):621–628PubMedCrossRef
15.
Zurück zum Zitat Seiffert M, Franzen O, Conradi L, Baldus S, Schirmer J, Meinertz T, Reichenspurner H, Treede H (2010) Series of transcatheter valve-in-valve implantations in high-risk patients with degenerated bioprostheses in aortic and mitral position. Catheter Cardiovasc Interv 76(4):608–615PubMedCrossRef Seiffert M, Franzen O, Conradi L, Baldus S, Schirmer J, Meinertz T, Reichenspurner H, Treede H (2010) Series of transcatheter valve-in-valve implantations in high-risk patients with degenerated bioprostheses in aortic and mitral position. Catheter Cardiovasc Interv 76(4):608–615PubMedCrossRef
16.
Zurück zum Zitat Eggebrecht H, Schäfer U, Treede H, Boekstegers P, Babin-Ebell J, Ferrari M, Möllmann H, Baumgartner H, Carrel T, Kahlert P, Lange P, Walther T, Erbel R, Mehta RH, Thielmann M (2011) Valve-in-valve transcatheter aortic valve implantation for degenerated bioprosthetic heart valves. JACC Cardiovasc Interv 4(11):1218–1227PubMedCrossRef Eggebrecht H, Schäfer U, Treede H, Boekstegers P, Babin-Ebell J, Ferrari M, Möllmann H, Baumgartner H, Carrel T, Kahlert P, Lange P, Walther T, Erbel R, Mehta RH, Thielmann M (2011) Valve-in-valve transcatheter aortic valve implantation for degenerated bioprosthetic heart valves. JACC Cardiovasc Interv 4(11):1218–1227PubMedCrossRef
17.
Zurück zum Zitat Kempfert J, Van Linden A, Linke A, Borger MA, Rastan A, Mukherjee C, Ender J, Schuler G, Mohr FW, Walther T (2010) Transapical off-pump valve-in-valve implantation in patients with degenerated aortic xenografts. Ann Thorac Surg 89(6):1934–1941PubMedCrossRef Kempfert J, Van Linden A, Linke A, Borger MA, Rastan A, Mukherjee C, Ender J, Schuler G, Mohr FW, Walther T (2010) Transapical off-pump valve-in-valve implantation in patients with degenerated aortic xenografts. Ann Thorac Surg 89(6):1934–1941PubMedCrossRef
18.
Zurück zum Zitat Wilbring M, Sill B, Tugtekin SM, Alexiou K, Simonis G, Matschke K, Kappert U (2012) Transcatheter valve-in-valve implantation for deteriorated aortic bioprosthesis: initial clinical results and follow-up in a series of high-risk patients. Ann Thorac Surg 93(3):734–741PubMedCrossRef Wilbring M, Sill B, Tugtekin SM, Alexiou K, Simonis G, Matschke K, Kappert U (2012) Transcatheter valve-in-valve implantation for deteriorated aortic bioprosthesis: initial clinical results and follow-up in a series of high-risk patients. Ann Thorac Surg 93(3):734–741PubMedCrossRef
19.
Zurück zum Zitat Motloch LJ, Rottlaender D, Reda S, Larbig R, Bruns M, Müller-Ehmsen J, Strauch J, Madershahian N, Erdmann E, Wahlers T, Hoppe UC (2012) Local versus general anesthesia for transfemoral aortic valve implantation. Clin Res Cardiol 101(1):45–53PubMedCrossRef Motloch LJ, Rottlaender D, Reda S, Larbig R, Bruns M, Müller-Ehmsen J, Strauch J, Madershahian N, Erdmann E, Wahlers T, Hoppe UC (2012) Local versus general anesthesia for transfemoral aortic valve implantation. Clin Res Cardiol 101(1):45–53PubMedCrossRef
20.
Zurück zum Zitat Leon MB, Piazza N, Nikolsky E, Blackstone EH, Cutlip DE, Kappetein AP, Krucoff MW, Mack M, Mehran R, Miller C, Morel MA, Petersen J, Popma JJ, Takkenberg JJ, Vahanian A, van Es GA, Vranckx P, Webb JG, Windecker S, Serruys PW (2011) Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium. Eur Heart J 32(2):205–217PubMedCrossRef Leon MB, Piazza N, Nikolsky E, Blackstone EH, Cutlip DE, Kappetein AP, Krucoff MW, Mack M, Mehran R, Miller C, Morel MA, Petersen J, Popma JJ, Takkenberg JJ, Vahanian A, van Es GA, Vranckx P, Webb JG, Windecker S, Serruys PW (2011) Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium. Eur Heart J 32(2):205–217PubMedCrossRef
21.
Zurück zum Zitat Rahimtoola SH (2003) Choice of prosthetic heart valve for adult patients. J Am Coll Cardiol 41(6):893–904PubMedCrossRef Rahimtoola SH (2003) Choice of prosthetic heart valve for adult patients. J Am Coll Cardiol 41(6):893–904PubMedCrossRef
22.
Zurück zum Zitat Azadani AN, Jaussaud N, Matthews PB, Ge L, Chuter TA, Tseng EE (2010) Transcatheter aortic valves inadequately relieve stenosis in small degenerated bioprostheses. Interact Cardiovasc Thorac Surg 11(1):70–77 (Epub 2010 Apr 15) Azadani AN, Jaussaud N, Matthews PB, Ge L, Chuter TA, Tseng EE (2010) Transcatheter aortic valves inadequately relieve stenosis in small degenerated bioprostheses. Interact Cardiovasc Thorac Surg 11(1):70–77 (Epub 2010 Apr 15)
23.
Zurück zum Zitat Gurvitch R, Cheung A, Bedogni F, Webb JG (2011) Coronary obstruction following transcatheter aortic valve-in-valve implantation for failed surgical bioprostheses. Catheter Cardiovasc Interv 77(3):439–444. doi:10.1002/ccd.22861 (Epub 2011 Jan 4)PubMedCrossRef Gurvitch R, Cheung A, Bedogni F, Webb JG (2011) Coronary obstruction following transcatheter aortic valve-in-valve implantation for failed surgical bioprostheses. Catheter Cardiovasc Interv 77(3):439–444. doi:10.​1002/​ccd.​22861 (Epub 2011 Jan 4)PubMedCrossRef
Metadaten
Titel
Transcatheter Edwards Sapien XT valve in valve implantation in degenerated aortic bioprostheses via transfemoral access
verfasst von
Martin Greif
Philipp Lange
Helmut Mair
Christoph Becker
Christoph Schmitz
Gerhard Steinbeck
Christian Kupatt
Publikationsdatum
01.12.2012
Verlag
Springer-Verlag
Erschienen in
Clinical Research in Cardiology / Ausgabe 12/2012
Print ISSN: 1861-0684
Elektronische ISSN: 1861-0692
DOI
https://doi.org/10.1007/s00392-012-0488-3

Weitere Artikel der Ausgabe 12/2012

Clinical Research in Cardiology 12/2012 Zur Ausgabe

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.