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01.12.2024 | Original Paper

Twelve-month outcomes of Kahook dual blade goniotomy combined with cataract surgery in Latino patients

verfasst von: Gustavo Espinoza, Manuel Jose Justiniano, Ignacio Rodriguez-Una, Fernando Godin, Andres Arango, Sylvia Villamizar

Erschienen in: International Ophthalmology | Ausgabe 1/2024

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Abstract

Purpose

To evaluate 12 month surgical outcome of Kahook Dual Blade (KDB) goniotomy in combination with cataract surgery in Latino patients with open angle glaucoma (OAG) and ocular hypertension (OHT).

Methods

This retrospective study included 45 eyes of 40 patients who underwent KDB goniotomy combined with cataract extraction from January 2016 to September 2020 at two centers in South America. Primary outcome was surgical success defined as ≥ 20% intraocular pressure (IOP) reduction or ≥ 1 medication reduction from preoperative without additional IOP-lowering procedures and an IOP ≥ 5 mmHg or ≤ 21 mmHg. Additionally, we used 2 cutoffs values for success of IOP ≤ 18 and ≤ 15 mmHg. Secondary outcomes included: IOP, medication use, best corrected visual acuity, complications and failure-associated factors.

Results

Success rates at 12 months with cutoff limits of 21, 18 and 15 mmHg were 84.3%, 75.6% and 58.7%, respectively. At 12 months, mean preoperative IOP significantly decreased from 19.23 ± 0.65 mmHg on 2.3 ± 1.0 medications to 14.33 ± 0.66 mmHg on 0.6 ± 0.9 medications (p < 0.001) , with 62% of eyes free of hypotensive medication. Eyes that developed postoperative IOP spikes showed a higher risk for failure using the cutoff limit of IOP ≤ 18 mmHg with a hazard ratio of 3.6 (95% confidence interval [CI], 1.80–7.13; p < 0.001). There were no serious ocular adverse events.

Conclusions

KDB combined with cataract extraction showed safety and efficacy for decreasing IOP in OAG and OHT Latino patients. Additionally, dependence on medications was reduced significantly after surgery.

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Titel: Twelve-month outcomes of Kahook dual blade goniotomy combined with cataract surgery in Latino patients
verfasst von: Gustavo Espinoza
Manuel Jose Justiniano
Ignacio Rodriguez-Una
Fernando Godin
Andres Arango
Sylvia Villamizar
Publikationsdatum: 01.12.2024
Verlag: Springer Netherlands
Erschienen in: International Ophthalmology / Ausgabe 1/2024
Print ISSN: 0165-5701
Elektronische ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-024-03024-w

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Twelve-month outcomes of Kahook dual blade goniotomy combined with cataract surgery in Latino patients

Abstract

Purpose

Methods

Results

Conclusions

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