02.05.2024 | Research letter
Unicentric mesenteric Castleman disease: Outcomes of surgical resection from a single institution
verfasst von:
Divakar Jain, Tanvi Shah, Shraddha Patkar, Sridhar Sundaram, Manish Bhandare, Mukta Ramadwar, Mahesh Goel
Erschienen in:
Indian Journal of Gastroenterology
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Excerpt
Castleman disease (CD) is a rare lymphoproliferative disorder described in 1954 by Dr. Benjamin Castleman. It can be unicentric or multi-centric on presentation. CD is often seen in patients with immune-deficiency status (HIV, long-term steroid therapy). CD is classified into hyaline vascular type, plasma cell type or mixed. Unicentric CD is commonly seen in mediastinum, neck and retroperitoneum. Unicentric mesenteric CD is rare and often creates diagnostic dilemma mimicking as lymphoma, tuberculosis or carcinoma. Pain or discomfort is the most common symptom; many cases are found incidentally during imaging. Potential symptoms arise from the size of the mass and the compression of surrounding structures The present case series is of five patients of unicentric mesenteric Castleman’s disease treated surgically (Table
1). …
