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European Archives of Psychiatry and Clinical Neuroscience

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01.04.2014 | Short Communication

Vagus somatosensory evoked potentials are delayed in Alzheimer’s disease, but not in major depression

verfasst von: Thomas Polak, Thomas Dresler, Julia B. M. Zeller, Bodo Warrings, Peter Scheuerpflug, Andreas J. Fallgatter, Jürgen Deckert, Florian G. Metzger

Erschienen in: European Archives of Psychiatry and Clinical Neuroscience | Ausgabe 3/2014

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Abstract

In Alzheimer’s disease (AD), the degeneration of brainstem nuclei is different from major depression (MD). Thus, vagus somatosensory evoked potentials (VSEP) proposed for the functional assessment of brainstem nuclei should show prolonged latencies in AD but not in MD. In 55 AD patients, 57 MD patients and two age-matched control groups evoked potentials were recorded upon stimulation of the auricular branch of the vagus nerve. In the AD, not in the MD group, latencies were significantly longer as compared to controls. Thus, the method of VSEP could contribute to the important differential diagnosis of AD and MD in elderly patients.

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Titel: Vagus somatosensory evoked potentials are delayed in Alzheimer’s disease, but not in major depression
verfasst von: Thomas Polak
Thomas Dresler
Julia B. M. Zeller
Bodo Warrings
Peter Scheuerpflug
Andreas J. Fallgatter
Jürgen Deckert
Florian G. Metzger
Publikationsdatum: 01.04.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: European Archives of Psychiatry and Clinical Neuroscience / Ausgabe 3/2014
Print ISSN: 0940-1334
Elektronische ISSN: 1433-8491
DOI: https://doi.org/10.1007/s00406-013-0415-2

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