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Erschienen in: Intensive Care Medicine 6/2017

06.04.2017 | What's New in Intensive Care

What’s new in pharmacokinetics of antimicrobials in AKI and RRT?

verfasst von: Jason A. Roberts, Jean-Yves Lefrant, Jeffrey Lipman

Erschienen in: Intensive Care Medicine | Ausgabe 6/2017

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Excerpt

Acute kidney injury (AKI) remains a very common occurrence in critically ill patients and is associated with decreased survival in severe sepsis [1]. Effective treatment for these patients is mostly through treatment of the underlying pathology as well as supportive care with renal replacement therapy (RRT). Optimised pharmacotherapy is of heightened importance to ensure maximal outcomes for critically ill patients with AKI receiving RRT, although the pharmacokinetics of many drugs can change dramatically in these patients, making effective dosing a challenge. …
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Metadaten
Titel
What’s new in pharmacokinetics of antimicrobials in AKI and RRT?
verfasst von
Jason A. Roberts
Jean-Yves Lefrant
Jeffrey Lipman
Publikationsdatum
06.04.2017
Verlag
Springer Berlin Heidelberg
Erschienen in
Intensive Care Medicine / Ausgabe 6/2017
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-017-4789-x

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