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The Anatomy and Physiology Metabolism/Nutrition of Subcutaneous Fat

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Liposuction

5.14 Conclusions

Both the microscopic and the gross anatomy of the fat mass should be appreciated by the liposuction surgeon. With this appreciation a better result can be expected, especially in understanding the caveat to not injure the dermis during a procedure.

The physiology depends on an appreciation for colloid osmotic pressure, which is significantly reduced by Klein’s tumescent solution. This wash-down of interstitial protein would enhance flow of the solution into the vascular space if it were not for the effect of epinephrine. Nevertheless using a massive amount of tumescent solution can overwhelm the right side of heart and cause congestive heart failure.

The fat mass is dynamic. The fact that adipocytes can differentiate and dedifferentiate is exciting in their application to redifferentiation into other cell types. Stem cells from lipoaspirate make more sense than bone marrow or embryonic sources.

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Kaminski, M.V., Lopez de Vaughan, R.M. (2006). The Anatomy and Physiology Metabolism/Nutrition of Subcutaneous Fat. In: Liposuction. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-28043-X_5

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  • DOI: https://doi.org/10.1007/3-540-28043-X_5

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