Abstract
The recent development of combined positron emission tomography/computed tomography (PET/CT) instrumentation is an important evolution in imaging technology. Since the introduction of the first prototype CT scanner in the early 1970s, tomographic imaging has made significant contributions to the diagnosis and staging of disease. Rapid commercial development followed the introduction of the first CT scanner in 1972, and within 3 years of its appearance more than 12 companies were marketing, or intending to market, CT scanners; about half that number actually market CT scanners today. With the introduction of magnetic resonance imaging (MRI) in the early 1980s, CT was, at that time, predicted to last another 5 years at most before being replaced by MRI for anatomical imaging. Obviously, this did not happen, and today, with multislice detectors, spiral acquisition, and subsecond rotation times, CT continues to develop and to play a major role in clinical imaging, in particular for the assessment of cardiovascular disease. Indeed, one of the main driving forces for the current development in CT is for applications in cardiology.
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References
Townsend DW, Cherry SR. Combining anatomy with function: the path to true image fusion. Eur Radiol. 2001;11:1968–1974.
Beyer T, Townsend DW, Brun T, et al. A combined PET/CT scanner for clinical oncology. JNucl Med. 2000;41:1369–1379.
Charron M, Beyer T, Bohnen NN, et al. Image analysis in patients with cancer studied with a combined PET and CT scanner. Clin Nucl Med. 2000;25:905–910.
Meltzer CC, Martinelli MA, Beyer T, et al. Whole-body FDG PET imaging in the abdomen: value of combined PET/CT. J Nucl Med. 2001;42:35P.
Meltzer CC, Snyderman CH, Fukui MB, et al. Combined FDG PET/CT imaging in head and neck cancer: impact on patient management. J Nucl Med. 2001;42:36P.
Kluetz PG, Meltzer CC, Villemagne VL, et al. Combined PET/CT imaging in oncology: impact on patient management. Clin Positron Imaging. 2000;3:223–230.
Hawkes DJ, Hill DL, Hallpike L, Bailey DL. Coregistration of Structural and Functional Images. In: Valk P, Bailey DL, Townsend DW, Maisey MN, eds. Positron Emission Tomography: Basic Science and Clinical Practice. Springer, London, New York, 2003:181–197.
Townsend DW, Beyer T, Blodgett TM. PET/CT scanners: a hardware approach to image fusion. Semin Nucl Med. 2003;33:193–204.
Kinahan PE, Townsend DW, Beyer T, Sashin D. Attenuation correction for a combined 3D PET/CT scanner. Med Phys. 1998;25:2046–2053.
Burger C, Goerres G, Schoenes S, et al. PET attenuation coefficients from CT images: experimental evaluation of the transformation of CT into PET 511-keV attenuation coefficients. Eur J Nucl Med Mol Imaging. 2002;29:922–927.
Rappoport V, Carney JPJ, Townsend DW. X-ray tube voltage dependent attenuation correction scheme for PET/CT scanners. IEEE Medical Imaging Conference Record. 2004; M10-76:213.
Koepfli P, Hany TF, Wyss CA, et al. CT attenuation correction for myocardial perfusion quantification using a PET/CT hybrid scanner. J Nucl Med. 2004;45:537–542.
Bigger JT. Expanding indications for implantable cardiac defibrillators. N Engl J Med. 2002;346:931–933.
Moss A, Zareba W, Hall W, et al, for the Multicenter Automatic Defibrillator Implantation Trial II Investigators. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346:877–883.
Antoch G, Freudenberg LS, Egelhof T, et al. Focal tracer uptake: a potential artifact in contrast-enhanced dual-modality PET/CT scans. J Nucl Med. 2002;43:1339–1342.
Goerres GW, Ziegler SI, Burger C, Berthold T, von Schulthess GK, Buck A. Artifacts at PET and PET/CT caused by metallic hip prosthetic material. Radiology. 2003;226:577–584.
Kamel EM, Burger C, Buck A, von Schulthess GK, Goerres GW. Impact of metallic dental implants on CT-based attenuation correction in a combined PET/CT scanner. Eur Radiol. 2003;13:724–728.
Halpern BS, Dahlbom M, Waldherr C, et al. Cardiac pacemakers and central venous lines can induce focal artifacts on CT-corrected PET images. J Nucl Med. 2004;45:290–293.
DiFilippo FP, Brunken RC. Do implanted pacemaker leads and ICD leads cause metalrelated artifact in cardiac PET/CT? J Nucl Med. 2005;46:436–443.
Keall PJ, Starkschall G, Shukla H, et al. Acquiring 4D thoracic CT scans using a multislice helical method. Phys Med Biol. 2004;49:2053–2067.
Townsend DW, Yap JT, Carney JP, et al. Respiratory gating with a 16-slice LSO PET/CT scanner. J Nucl Med. 2004;45S:165P–166P.
William W. The diagnosis of coronary artery disease: in search of a one-stop shop. J Nucl Med. 2005;46:904–905.
Namdar M, Hany TF, Koepfli P, et al. Integrated PET/CT for the assessment of coronary artery disease: a feasibility study. J Nucl Med. 2005;46:930–935.
Loghin C, Sdringola S, Gould KL. Common artifacts in PET myocardial perfusion images due to attenuation-emission misregistration: clinical significance, causes, and solutions. J Nucl Med. 2004;45:1029–1039.
Wilson JW, Wong TZ, Borges-Neto F, Turkington TG. An algorithm for correction of PET/CT mismatch-induced cardiac attenuation correction artifacts. J Nucl Med. 2005;46S:55P.
Hudson H, Larkin R. Accelerated image reconstruction using ordered subsets of projection data. IEEE Trans Med Imaging. 1994;13:601–609.
Defrise M, Kinahan PE, Townsend DW, Michel C, Sibomana M, Newport DF. Exact and approximate rebinning algorithms for 3D PET data. IEEE Trans Med Imaging. 1997;16:145–158.
Comtat C, Kinahan PE, Defrise M, et al. Fast reconstruction of 3D PET data with accurate statistical modeling. IEEE Trans Nucl Sci. 1998;45:1083–1089.
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Townsend, D.W., Besozzi, M.C., Carney, J.P.J. (2007). Integrated PET/CT. In: Di Carli, M.F., Lipton, M.J. (eds) Cardiac PET and PET/CT Imaging. Springer, New York, NY. https://doi.org/10.1007/978-0-387-38295-1_3
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DOI: https://doi.org/10.1007/978-0-387-38295-1_3
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