Skip to main content

Diastolic Dysfunction and Cardiac Failure in the Intensive Care Unit

  • Conference paper
Intensive Care Medicine
  • 1190 Accesses

Abstract

With the advent of newer technology, recognition of diastolic dysfunction has become a major feature of cardiac disease, in heart failure as in septic shock. Doppler echocardiography plays a pivotal role in the evaluation of both systolic and diastolic function. Preserved systolic function, in conjunction with diastolic dysfunction, is an early sign of cardiac failure. Therefore, early diagnosis of diastolic failure is warranted. In recent years, measurement of intra-myocardial tissue Doppler velocities and deformations of the myocardial wall have attracted the attention of many researchers. In this chapter, the most recent echocardiographic and Doppler applications, based on wave progression, pressure gradients, mitral valve leaflet and annular motion, and ventricular rotation will be discussed to give the critical care specialist a better insight into the diagnosis of diastolic dysfunction.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Brutsaert DL, Rademakers FE, Sys SU, Gillebert TC, Housmans PR (1985) Analysis of relaxation in the evaluation of ventricular function of the heart. Prog Cardiovasc Dis 28:143–163

    Article  PubMed  CAS  Google Scholar 

  2. Brutsaert DL, Rademakers FE, Sys SU, Gillebert TC, Housmans PR (1984) The heart as an integrated muscle and pump system: triple control and subdivision of the cardiac cycle. Acta Cardiol 39:89–95

    PubMed  CAS  Google Scholar 

  3. Gillebert T, Leite-Moreira A, De Hert S (1997) The hemodynamic manifestation of normal myocardial relaxation. A framework for experimental and clinical evaluation. Acta Cardiologica 52:223–246

    PubMed  CAS  Google Scholar 

  4. De Hert S, Gillebert T, Ten Broecke P, Mertens E, Rodrigus I, Moulijn A (1999) Contractionrelaxation coupling and impaired left ventricular performance in coronary surgery patients. Anesthesiology 90:748–757

    Google Scholar 

  5. Ishizaka S, Asanoi H, Wada O, Kameyama T, Inoue H (1995) Loading sequence plays an important role in enhanced load sensitivity of left ventricular relaxation in conscious dogs with tachycardia-induced cardiomyopathy. Circulation 92:3560–3567

    PubMed  CAS  Google Scholar 

  6. Leeuwenburgh BP, Steendijk P, Helbing WA, Baan J (2002) Indexes of diastolic RV function: load dependence and changes after chronic RV pressure overload in lambs. Am J Physiol Heart Circ Physiol 282:H1350–1358

    PubMed  CAS  Google Scholar 

  7. Leite-Moreira A, Correia-Pinto J, Gillebert T (1999) Load dependence of left ventricular contraction and relaxation. Effects of caffeine. Basic Research in Cardiology 94:284–293

    Article  PubMed  CAS  Google Scholar 

  8. Leite-Moreira A, Gillebert T (1994) Nonuniform course of left ventricular pressure fall and its regulation by load and contractile state. Circulation 90:2481–2491

    PubMed  CAS  Google Scholar 

  9. Varian KD, Janssen PM (2007) Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity. Am J Physiol Heart Circ Physiol 292:H2212–2219

    Article  PubMed  CAS  Google Scholar 

  10. Bombardini T (2005) Myocardial contractility in the echo lab: molecular, cellular and pathophysiological basis. Cardiovasc Ultrasound 3:27

    Article  PubMed  Google Scholar 

  11. Khouri SJ, Maly GT, Suh DD, Walsh TE (2004) A practical approach to the echocardiographic evaluation of diastolic function. J Am Soc Echocardiogr 17:290–297

    Article  PubMed  Google Scholar 

  12. Weiss JL, Frederiksen JW, Weisfeldt ML (1976) Hemodynamic determinants of the timecourse of fall in canine left ventricular pressure. J Clin Invest 58:751–760

    Article  PubMed  CAS  Google Scholar 

  13. Nikolic S, Yellin EL, Tamura K, et al (1988) Passive properties of canine left ventricle: diastolic stiffness and restoring forces. Circ Res 62:1210–1222

    PubMed  CAS  Google Scholar 

  14. Little WC, Ohno M, Kitzman DW, Thomas JD, Cheng CP (1995) Determination of left ventricular chamber stiffness from the time for deceleration of early left ventricular filling. Circulation 92:1933–1939

    PubMed  CAS  Google Scholar 

  15. Poelaert J, Declerck C, Vogelaers D, Colardyn F, Visser CA (1997) Left ventricular systolic and diastolic function in septic shock. Intensive Care Med 23:553–560

    Article  PubMed  CAS  Google Scholar 

  16. Isaaz K, Thompson A, Ethevenot G, Cloez JL, Brembilla B, Pernot C (1989) Doppler echocardiographic measurement of low velocity motion of the left ventricular posterior wall. Am J Cardiol 64:66–75

    Article  PubMed  CAS  Google Scholar 

  17. McDicken WN, Sutherland GR, Moran CM, Gordon LN (1992) Colour Doppler velocity imaging of the myocardium. Ultrasound Med Biol 18:651–654

    Article  PubMed  CAS  Google Scholar 

  18. Garcia MJ, Thomas JD, Klein AL (1998) New Doppler echocardiographic applications for the study of diastolic function. J Am Coll Cardiol 32:865–875

    Article  PubMed  CAS  Google Scholar 

  19. Miyatake K, Yamagishi M, Tanaka N, et al (1995) New method of evaluating left ventricular wall motion by color-coded tissue Doppler imaging: in vitro and in vivo studies. J Am Coll Cardiol 25:717–724

    Article  PubMed  CAS  Google Scholar 

  20. Ommen SR, Nishimura RA, Appleton CP, et al (2000) Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: A comparative simultaneous Doppler-catheterization study. Circulation 102:1788–1794

    PubMed  CAS  Google Scholar 

  21. Ama R, Segers P, Roosens C, Claessens T, Verdonck P, Poelaert J (2004) Effects of load on systolic mitral annular velocity by tissue Doppler imaging. Anesth Analg 99:332–338

    PubMed  Google Scholar 

  22. Poelaert J, Roosens C (2007) Is tissue Doppler echocardiography the Holy Grail for the intensivist? Crit Care 11:135

    Article  PubMed  Google Scholar 

  23. Jacques DC, Pinsky MR, Severyn D, Gorcsan J, III (2004) Influence of Alterations in Loading on Mitral Annular Velocity by Tissue Doppler Echocardiography and Its Associated Ability To Predict Filling Pressures. Chest 126:1910–1918

    Article  PubMed  Google Scholar 

  24. Vignon P, Allot V, Lesage J, Martaillé J-F, François B, Gastinne H (2007) Diagnosis of left ventricular diastolic dysfunction in the setting of acute changes in loading conditions. Crit Care 11:R43

    Article  PubMed  Google Scholar 

  25. Roosens CD, Ama R, Leather HA, et al (2006) Hemodynamic effects of different lung-protective ventilation strategies in closed-chest pigs with normal lungs. Crit Care Med 34:2990–2996

    PubMed  Google Scholar 

  26. von Bibra H, Tuchnitz A, Klein A, Schneider-Eicke J, Schomig A, Schwaiger M (2000) Regional diastolic function by pulsed Doppler myocardial mapping for the detection of left ventricular ischemia during pharmacologic stress testing: a comparison with stress echocardiography and perfusion scintigraphy. J Am Coll Cardiol 36:444–452

    Article  Google Scholar 

  27. Nagueh SF, Sun H, Kopelen HA, Middleton KJ, Khoury DS (2001) Hemodynamic determinants of the mitral annulus diastolic velocities by tissue Doppler. J Am Coll Cardiol 37:278–285

    Article  PubMed  CAS  Google Scholar 

  28. D’hooghe J, Jamal F, Bijnens B, et al (2000) Calculation of strain values from strain rate values: how should this be done ? In: IEEE International Ultrasonics Symposium Proceedings, pp 1269–1272

    Google Scholar 

  29. Weil M (1998) The assault on the Swan Ganz catheter. A case history of constrained technology, constrained bedside clinicians, and constrained monetary expenditures. Chest 113: 1379–1386

    Article  PubMed  CAS  Google Scholar 

  30. Michel-Cherqui M, Ceddaha A, Liu N, et al (2000) Assessment of systematic use of intraoperative transesophageal echocardiographic during cardiac surgery in adults: a prospective study of 203 patients. J Cardiothorac Vasc Anesth 14:45–50

    Article  PubMed  CAS  Google Scholar 

  31. Pruszczyk P, Torbicki A, Kuch-Wocial A, Szulc M, Pacho R (2001) Diagnostic value of transoesophageal echocardiography in suspected haemodynamically significant pulmonary embolism. Heart 85:628–634

    Article  PubMed  CAS  Google Scholar 

  32. Poelaert J (2006) The failing heart under stress: echocardiography is an essential monitoring tool in the intensive care unit. Semin Cardiothorac Vasc Anesth 10:111–115

    Article  PubMed  Google Scholar 

  33. Poelaert JI, Schupfer G (2005) Hemodynamic monitoring utilizing transesophageal echocardiography: The relationships among pressure, flow, and function. Chest 127:379–390

    Article  PubMed  Google Scholar 

  34. Nagueh S, Mikati I, Kopelen H, Middleton K, Quinonens M, Zoghbi W (1998) Doppler estimation of left ventricular filling pressure in sinus tachycardia. A new application of tissue Doppler imaging. Circulation 98:1644–1650

    PubMed  CAS  Google Scholar 

  35. Combes A, Arnoult F, Trouillet JL (2004) Tissue Doppler imaging estimation of pulmonary artery occlusion pressure in ICU patients. Intensive Care Med 30:75–81

    Article  PubMed  Google Scholar 

  36. Bouhemad B, Nicolas-Robin A, Benois A, Lemaire S, Goarin JP, Rouby JJ (2003) Echocardiographic Doppler assessment of pulmonary capillary wedge pressure in surgical patients with postoperative circulatory shock and acute lung injury. Anesthesiology 98:1091–1100

    Article  PubMed  Google Scholar 

  37. D’Souza KA, Mooney DJ, Russell AE, Maclsaac AI, Aylward PE, Prior DL (2005) Abnormal septal motion affects early diastolic velocities at the septal and lateral mitral annulus, and impacts on estimation of the pulmonary capillary wedge pressure. J Am Soc Echocardiogr 18:445–453

    Article  Google Scholar 

  38. Poelaert J, Mayo P (2007) Education and evaluation of knowledge and skills in echocardiography: how should we organize? Intensive Care Med 33:1684–1686

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer Science + Business Media Inc.

About this paper

Cite this paper

Poelaert, J., Osipowska, E., Verborgh, C. (2008). Diastolic Dysfunction and Cardiac Failure in the Intensive Care Unit. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-0-387-77383-4_8

Download citation

  • DOI: https://doi.org/10.1007/978-0-387-77383-4_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-77382-7

  • Online ISBN: 978-0-387-77383-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics