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Vascular Glucose Transport and the Metabolic Syndrome

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Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome

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Abstract

The metabolic syndrome comprises a wide range of physiopathological abnormalities, all involved in systemic changes, occurring in different territories of the body. Glucose transporter changes throughout the body are observed in diverse degrees in the metabolic syndrome. This chapter aims to describe the alterations of glucose transport associated with the metabolic syndrome occurring at the vascular level. We will highlight the mechanisms regulating glucose transport in endothelial and vascular smooth muscle cells derived from peripheral vascular beds and from the blood-brain and blood-retinal barriers. Knowledge on this subject will contribute for understanding the physiopathology of the metabolic syndrome, as well as possible treatments for this condition.

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Authors and Affiliations

  1. Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal

    Fatima Martel

  2. Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Al. Prof. Hernâni Monteiro, 4200-319, Porto, Portugal

    Elisa Keating

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  1. Fatima Martel
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Editors and Affiliations

  1. Department of Biochemistry (U38/CFT) Faculty of Medicine, University of Porto Al. Prof. Hernani Monteiro, 4200-319 Postage, Portugal

    Raquel Soares (Dr) (Dr)

  2. Department of Biochemistry (U38/CFT) Laboratory for Molecular Cell Biology Faculty of Medicine, University of Porto Al. Prof. Hernani Monteiro, 4200-319 Postage, Portugal

    Carla Costa (Dr) (Dr)

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Martel, F., Keating, E. (2009). Vascular Glucose Transport and the Metabolic Syndrome. In: Soares, R., Costa, C. (eds) Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-9701-0_7

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