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A non-genetic development defect in trophoblast formation in the horse: immunological aspects of a model of early abortion

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Early Pregnancy Loss

Abstract

Embryogenesis and placentation in the horse family (Genus equus) is unusual and interesting for several reasons. For example: a) the chorion of the equine conceptus is composed of two morphologically and functionally distinct forms of trophoblast which can be studied in situ and in vitro; (1.2) b) there is evidence for strong humoral(3) and cell-mediated maternal(4) anti-fetal immune responses in normal intraspecies equine pregnancy; c) member species of the genus have the capacity to interbreed to produce viable, but usually infertile, hybrid offspring;(5) d) embryo transfer can be performed successfully between many member species of the genus with the birth of live foals. (6)

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Authors
  1. D. F. Antczak
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  2. W. R. Allen
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Editor information

Editors and Affiliations

  1. Department of Obstetrics and Gynaecology, Northern General Hospital, Herries Road, Sheffield, S5 7AU, UK

    Frank Sharp MD, FRCOG

  2. Department of Obstetrics and Gynaecology, St Mary’s Hospital, Praed Street, London, W2 1PG, UK

    Richard W. Beard MB, BChir(Cantab), MD, FRCOG

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© 1988 The Royal College of Obstetricians and Gynaecologists

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Antczak, D.F., Allen, W.R. (1988). A non-genetic development defect in trophoblast formation in the horse: immunological aspects of a model of early abortion. In: Sharp, F., Beard, R.W. (eds) Early Pregnancy Loss. Springer, London. https://doi.org/10.1007/978-1-4471-1658-5_14

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  • DOI: https://doi.org/10.1007/978-1-4471-1658-5_14

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1660-8

  • Online ISBN: 978-1-4471-1658-5

  • eBook Packages: Springer Book Archive

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