Skip to main content
SpringerLink
Log in

Treatment of Retinal Detachment

  • Chapter
Ophthalmic Histopathology

  • 181 Accesses

Abstract

This chapter serves primarily as a guide to the causative pathology and the secondary disturbances which are encountered when an enucleated eye is submitted with a clinical history of “Retinal detachment — treatment unsuccessful”. With technical advancement and a more aggressive surgical approach to trauma and diabetes, such specimens, although rare, are being submitted more frequently than in the past and will also be available via the Autopsy Service. In addition, clinicopathological correlation is more significant in view of the development of new surgical techniques which are described in the literature.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 74.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Akiba J, Quiroz MA, Trempe CL (1990) Role of posterior vitreous detachment in idiopathic macular holes. Ophthalmology 97:1610–1613

    PubMed  CAS  Google Scholar 

  • Azuara-Blanco A, Dua HS, Pillai CT (1999) Pseudoendothelial dystrophy associated with emulsified silicon oil. Cornea 18:493–494

    Article  PubMed  CAS  Google Scholar 

  • Barr CC (1990) The histopathology of successful retinal reattachment. Retina 10:189–194

    PubMed  CAS  Google Scholar 

  • Bock GR, Widdows K (eds) (1990) Myopia and the Control of Eye Growth. Ciba Foundation Symposium 155. John Wiley and Sons, Chichester

    Google Scholar 

  • Boldrey EE, Egbert P, Gass JDM, Friberg T (1985) The histopathology of familial exudative vitreoretinopathy. Arch Ophthalmol 103:238–241

    Article  PubMed  CAS  Google Scholar 

  • Boulton M, Foreman D, Williams G, Mcleod D (1998) VEGF localisation in diabetic retinopathy. Br J Ophthalmol 82:561–568

    Article  PubMed  CAS  Google Scholar 

  • Carlsson EC, Bjork NJ (1990) SEM and TEM analysis of isolated human retinal microvessel membranes in diabetic retinopathy. Anat Rec 226:295–306

    Article  Google Scholar 

  • Casaroli-Marano RP, Pagan R, Vilaro S (1999) Epithelial-mesenchymal transition in proliferative vitreoretinopathy: intermediate filament protein expression in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 40:2062–2072

    PubMed  CAS  Google Scholar 

  • Chang C-J, Lai WW, Edward DP, Tso MOM (1995) Apoptotic photoreceptor cell death after traumatic retinal detachment in humans. Arch Ophthalmol 113:880–886

    Article  PubMed  CAS  Google Scholar 

  • Charteris DG, Hiscott P, Grierson I, Lightman SL (1992) Proliferative vitreo-retinopathy. Lymphocytes in epiretinal membranes. Ophthalmology 99:1364–1367

    PubMed  CAS  Google Scholar 

  • Chen Y-S, Hackett SF, Schoenfeld C-L, Vinores MA, Vinores SA, Campochiaro PA (1997) Localisation of vascular endothelial growth factor and its receptors to cells of vascular and avascular epiretinal membranes. Br J Ophthalmol 81:919–926

    Article  PubMed  CAS  Google Scholar 

  • Cherfan GM, Smiddy WE, Michels RG, de la Cruz Z et al. (1988) Clinicopathologic correlation of pigmented epiretinal membranes. Am J Ophthalmol 106:536–545

    Article  PubMed  CAS  Google Scholar 

  • Condon GP, Brownstein S, Wang NS, Kearns AF, Ewing CC (1986) Congenital hereditary (juvenile X-linked) retinoschisis. Histopathologic and ultrastructural findings in three eyes. Arch Ophthalmol 104:576–583

    Article  PubMed  CAS  Google Scholar 

  • Curtin BJ (1985) The Myopias: Basic Science and Clinical Management. Harper & Row, Philadelphia, pp 3–15

    Google Scholar 

  • Daicker B (1978) The macular fatty degeneration of the peripheral retina. Albrecht von Graefes Arch Ophthalmol 205:147–155

    CAS  Google Scholar 

  • D’hermies F, Korobelnik JF, Chauvaud D, Pouliquen Y et al. (1999) Scleral and episcleral histological changes related to encircling explants in 20 eyes. Acta Ophthalmol Scand 77:279–285

    Article  PubMed  Google Scholar 

  • Eckardt C, Nicolai U, Czank M, Schmidt D (1992) Identification of silicone oil in the retina after intravitreal injection. Retina 12:S17-S22

    Article  PubMed  CAS  Google Scholar 

  • Eller AW, Friberg TR, Mah F (2000) Migration of silicone oil into the brain: a complication of intraocular silicone oil for retinal tamponade. Am J Ophthalmol 129:685–688

    Article  PubMed  CAS  Google Scholar 

  • Federman JL, Eagle RC (1990) Extensive peripheral retinectomy combined with posterior 360(retinopathy for retinal reattachment in advanced proliferative vitreoretinopathy cases. Ophthalmology 97:1305–1320

    PubMed  CAS  Google Scholar 

  • Foos RY, Allen RA (1967) Retinal tears and lesser lesions of the peripheral retina in autopsy eyes. Am J Ophthalmol 64:643–655

    PubMed  Google Scholar 

  • Foos RY, Freeman SS (1970) Reticular cystoid degeneration of the peripheral retina. Am J Ophthalmol 69:392–403

    PubMed  CAS  Google Scholar 

  • Foulks GN, Hatchell DL, Proia AD, Klintworth GK (1991) Histopathology of silicone oil keratopathy in humans. Cornea 10:29–37

    PubMed  CAS  Google Scholar 

  • Frank RN, Amin RH, Elliot D, Puklin JE, Abrams GW (1996) Basic fibroblast growth factor and vascular endothelial growth factor are present in epiretinal and choroidal neovascular membranes. Am J Ophthalmol 122:393–403

    PubMed  CAS  Google Scholar 

  • Gass JDM (1988) Idiopathic senile macular hole. Its early stages and pathogenesis. Arch Ophthalmol 106:629–639

    Article  PubMed  CAS  Google Scholar 

  • George NDL, Yates JRW, Moore AT (1996) Clinical features in affected males with X-linked retinoschisis. Arch Ophthalmol 114:274–280

    Article  PubMed  CAS  Google Scholar 

  • Glaser BM, Carter JB, Kuppermann BD, Michels RG (1991) Perfluorooctane in the treatment of giant retinal tears with proliferative vitreoretinopathy. Ophthalmology 98: 1613–1621

    PubMed  CAS  Google Scholar 

  • Glazer LC, Maguire A, Blumenkranz MS, Trese MT, Green WR (1995) Improved surgical treatment of familial exudative vitreoretinopathy. Am J Ophthalmol 120:471–479

    PubMed  CAS  Google Scholar 

  • Grierson I, Mazure A, Hogg P, Hiscott P, Sheridan C. Wong D (1996) Nonvascular vitreoretinopathy: the cells and the cellular basis of contraction. Eye 10:671–684

    Article  PubMed  Google Scholar 

  • Hiscott P, Gray R, Grierson I, Gregor Z (1994) Cytokeratin-containing cells in proliferative diabetic retinopathy membranes. Br J Ophthalmol 78:219–222

    Article  PubMed  CAS  Google Scholar 

  • Hiscott P, Wong D, Grierson I (2000) Challenges in ophthalmic pathology: the vitreoretinal membrane biopsy. Eye 14:549–559

    Article  PubMed  Google Scholar 

  • Ho AC, Guyer DR, Fine SL (1998) Macular hole. Sury Ophthalmol 42: 393–416

    Article  CAS  Google Scholar 

  • Hui Y-N, Goodnight R, Zhang X-J, Sorgente N, Ryan S (1988) Glial epiretinal membranes and contraction. Immunohistochemical and morphologic studies. Arch Ophthalmol 106:1280–1285

    Article  PubMed  CAS  Google Scholar 

  • Ishida S,Yamakazi K, Shinoda K, Kawashima S, Oguchi Y (2000) Macular hole retinal detachment in highly myopic eyes: ultrastructure of epiretinal membrane and clinicopathological correlation. Retina 20:176–183

    Article  PubMed  CAS  Google Scholar 

  • Lewis GP, Fisher SK (2000) Müller cell outgrowth after retinal detachment: association with cone photoreceptors. Invest Ophthalmol Vis Sci 41:1542–1545

    PubMed  CAS  Google Scholar 

  • Luthert PJ, Chong NH (1998) Photoreceptor rescue. Eye 12:591–596

    Article  PubMed  Google Scholar 

  • Mazzuca DE, Benson WE (1986) Central serous retinopathy: Variants. Sury Ophthalmol 31:170–174

    Article  CAS  Google Scholar 

  • Messmer EM, Heidenkummer HP, Kampik A (1998) Ultrastructure of epiretinal membranes associated with macular holes. Graefes Arch Clin Exp Ophthalmol 236:248–254

    Article  PubMed  CAS  Google Scholar 

  • Meyer E, Kurz GH (1963) Retinal pits: a study of pathological findings in two cases. Arch Ophthalmol 70:640–646

    Article  PubMed  CAS  Google Scholar 

  • Monshizadeh R, Samiy N, Haimovici R (1999) Management of retained intravitreal lens fragments after cataract surgery. Sury Ophthalmol 43:397–404

    Article  CAS  Google Scholar 

  • Morino I, Hiscott P, McKechnie N, Grierson I (1990) Variation in epiretinal membrane components with clinical duration of the proliferative tissue. Br J Ophthalmol 74:393–399

    Article  PubMed  CAS  Google Scholar 

  • Nakamura K, Refojo MF, Crabtree DV, Leong FL (1990) Analysis and fractionation of silicone oil and fluorosilicone oils for intraocular use. Invest Ophthalmol Vis Sci 31:2059–2069

    PubMed  CAS  Google Scholar 

  • Nork TM, Wallow IH, Sramek SJ, Stevens TS, De Venecia G (1990) Immuno-cytochemical study of an eye with proliferative vitreoretinopathy and retinal tacks. Retina 10:78–85

    Article  PubMed  CAS  Google Scholar 

  • Nork TM, Millechia LL, Strickland BD, Linberg JV, Chao G-M (1995) Selective loss of blue cones and rods in human retinal detachment. Arch Ophthalmol 113:1066–1073

    Article  PubMed  CAS  Google Scholar 

  • Ohira A, de Juan E Jr (1990) Characterization of glial involvement in proliferative diabetic retinopathy. Ophthalmologica 201:187–195

    Article  PubMed  CAS  Google Scholar 

  • O’Malley PF, Allen RA (1967) Peripheral cystoid degeneration of the retina: incidence and distribution in 1,000 autopsy cases. Arch Ophthalmol 77:769–776

    Article  PubMed  Google Scholar 

  • O’Malley PF, Allen RA, Straatsma BR, O’Malley CC (1965) Paving stone degeneration of the retina. Arch Ophthalmol 73:169–182

    Article  PubMed  Google Scholar 

  • Pastor JC (1998) Proliferative vitreoretinopathy: an overview. Sury Ophthalmol 43:3–18

    Article  CAS  Google Scholar 

  • Rosa RH, Glaser BM, de la Cruz, Z, Green WR (1996) Clinicopathologic correlation of an untreated macular hole and a macular hole treated by vitrectomy, transforming growth factor-ß2, and gas tamponade. Am J Ophthalmol 122:853–863

    PubMed  Google Scholar 

  • Scott JA, Damato BE, Smith PA, Gurney PWV (1994) Scleral explant mimicking malignant melanoma. Eye 8:606–608

    Article  PubMed  Google Scholar 

  • Smiddy WE, Michels RG, Green WR (1990) Morphology, pathology, and surgery of idiopathic vitreoretinal macular disorders. Retina 10:288–296

    PubMed  CAS  Google Scholar 

  • Smiddy WE, Michels RG, Gilbert HD, Green WR (1992) Clinicopathologic study of idiopathic macular pucker in children and young adults. Retina 12:232–236

    Article  PubMed  CAS  Google Scholar 

  • Straatsma BR, Foos RY (1973) Typical and reticular degenerative retinoschisis. Am J Ophthalmol 75:551–575

    PubMed  CAS  Google Scholar 

  • Straatsma BR, Zeegen PD, Foos RY, Feman SS, Shabo AL (1974) Lattice degeneration of the retina. Am J Ophthalmol 77:619–649

    PubMed  CAS  Google Scholar 

  • To KW, Adamian M, Jakobiec FA, Berson EL (1996) Clinical and histopathologic findings in clumped pigmentary retinal degeneration. Arch Ophthalmol 114:950–955

    Article  PubMed  CAS  Google Scholar 

  • Toti P, Greco G, Montolese E, Stumpo M et al. (1999) Cell composition and immunohistochemical detection of VEGF, TGF-beta and TNFalpha in proliferative vitreoretinopathy. J Submicrosc Cytol Pathol 31:363–366

    PubMed  CAS  Google Scholar 

  • Winckler J, Lundsdorf H (2001) Ultrastructure and composition of asteroid bodies. Invest Ophthalmol Vis Sci 42;902–907

    Google Scholar 

  • Wong D, Lois N (2000) Foveal relocation by redistribution of the neurosensory retina. Br J Ophthalmol 84:352–357

    Article  PubMed  CAS  Google Scholar 

  • Young TL, Ronan SM, Alvear AB, Wildenberg SC et al. (1998) A second locus for familial high myopia maps to chromosome 12q. Am J Hum Genet 63:1419–1424

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, University of Glasgow, Western Infirmary, Glasgow, G11 6NT, UK

    William R. Lee (Honorary Senior Research Fellow)

Authors
  1. William R. Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag London

About this chapter

Cite this chapter

Lee, W.R. (2002). Treatment of Retinal Detachment. In: Ophthalmic Histopathology. Springer, London. https://doi.org/10.1007/978-1-4471-3910-2_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-3910-2_7

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-3912-6

  • Online ISBN: 978-1-4471-3910-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation