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Cellular Events Underlying the Regenerative Replacement of Lateral Line Sensory Epithelia in Amphibians

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The Mechanosensory Lateral Line

Abstract

In aquatic amphibians, removal of a patch of skin that contains lateral line neuromast organs evokes the production of new neuromasts that differentiate in the approximate location of the organs that were lost. The whole process can be completed in less than 2 weeks, with the number of replacement neuromasts roughly matching the number lost. This chapter attempts to explain some of the cellular mechanisms that lead to the regenerative replacement of lost neuromasts. It also discusses the potential generality of those mechanisms in regard to regeneration of cochlear hair cells, a recently discovered phenomenon that appears to result in recovery of function following profound sensorineural hearing loss in birds.

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© 1989 Springer-Verlag New York Inc.

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Corwin, J.T., Balak, K.J., Borden, P.C. (1989). Cellular Events Underlying the Regenerative Replacement of Lateral Line Sensory Epithelia in Amphibians. In: Coombs, S., Görner, P., Münz, H. (eds) The Mechanosensory Lateral Line. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3560-6_8

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  • DOI: https://doi.org/10.1007/978-1-4612-3560-6_8

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8157-3

  • Online ISBN: 978-1-4612-3560-6

  • eBook Packages: Springer Book Archive

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