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Suspicious for High-Grade Urothelial Carcinoma (Suspicious)

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The Paris System for Reporting Urinary Cytology

Abstract

The diagnosis of “suspicious for high-grade urothelial carcinoma (SHGUC)” is meant to reflect the presence of urothelial cells with severe atypia that falls short for a diagnosis of high-grade urothelial carcinoma (HGUC) but beyond atypia that is associated with the “atypical urothelial cells” (AUC). This chapter lists the quantitative and qualitative cytomorphologic criteria needed for a diagnosis of SHGUC.

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References

  1. Brimo F, Vollmer RT, Case B, Aprikian A, Kassouf W, Auger M. Accuracy of urine cytology and the significance of an atypical category. Am J Clin Pathol. 2009;132:785–93.

    Article  PubMed  Google Scholar 

  2. Piaton E, Decaussin-Petrucci M, Mege-Lechevallier F, Advenier AS, Devonec M, Ruffion A. Diagnostic terminology for urinary cytology reports including the new subcategories ‘atypical urothelial cells of undetermined significance’ (AUC-US) and ‘cannot exclude high grade’ (AUC-H). Cytopathology. 2014;25:27–38.

    Article  CAS  PubMed  Google Scholar 

  3. Raitanen MP, Aine RA, Kaasinen ES, Liukkonen TJ, Kylmälä TM, Huhtala H, Tammela TL, Finnbladder Group. Suspicious urine cytology (class III) in patients with bladder cancer: should it be considered as negative or positive? Scand J Urol Nephrol. 2002;36:213–7.

    Article  PubMed  Google Scholar 

  4. Rosenthal DL, VandenBussche CJ, Burroughs FH, Sathiyamoorthy S, Guan H, Owens C. The Johns Hopkins Hospital template for urologic cytology samples: part I—creating the template. Cancer Cytopathol. 2013;121:5–20.

    Article  Google Scholar 

  5. Sternberg I, Rona R, Olsfanger S, Lew S, Leibovitch I. The clinical significance of class III (suspicious) urine cytology. Cytopathology. 2011;22:329–33.

    Article  CAS  PubMed  Google Scholar 

  6. VandenBussche CJ, Sathiyamoorthy S, Owens CL, Burroughs FH, Rosenthal DL, Guan H. The Johns Hopkins Hospital template for urologic cytology samples: parts II and III: improving the predictability of indeterminate results in urinary cytologic samples: an outcomes and cytomorphologic study. Cancer Cytopathol. 2013;121:21–8.

    Article  PubMed  Google Scholar 

  7. Ton Nu TN, Kassouf W, Ahmadi-Kaliji B, Charbonneau M, Auger M, Brimo F. The value of the “suspicious for urothelial carcinoma” cytology category: a correlative study of 4 years including 337 patients. Cancer Cytopathol. 2014;122:796–803.

    Article  PubMed  Google Scholar 

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Correspondence to Fadi Brimo .

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Brimo, F. et al. (2016). Suspicious for High-Grade Urothelial Carcinoma (Suspicious). In: Rosenthal, D., Wojcik, E., Kurtycz, D. (eds) The Paris System for Reporting Urinary Cytology. Springer, Cham. https://doi.org/10.1007/978-3-319-22864-8_5

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  • DOI: https://doi.org/10.1007/978-3-319-22864-8_5

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-22863-1

  • Online ISBN: 978-3-319-22864-8

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