Abstract
Although the choice of biopsy type largely depends on the particular clinical setting and the experience of the team, core needle biopsy (CBN) is recommended as the first-choice procedure for obtaining representative specimens of soft tissue tumors for histologic and immunohistochemical examination. It allows one-surgery or neoadjuvant chemotherapy planning when combined with appropriate imaging. It can be performed under (PET)–CT or ultrasound guidance, CT being preferred for deep-seated lesions or those that are difficult to reach. The entry point and the pathway are determined in cross talk with the managing surgeon. Tissue sample fixation is adapted to permit immunohistochemical characterization.
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Gielen, J. (2017). Biopsy of Soft Tissue Tumors. In: Vanhoenacker, F., Parizel, P., Gielen, J. (eds) Imaging of Soft Tissue Tumors. Springer, Cham. https://doi.org/10.1007/978-3-319-46679-8_7
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DOI: https://doi.org/10.1007/978-3-319-46679-8_7
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