Abstract
Radiolabeled Choline (labeled to 11C or 18F) is one of the most applied and promising PET tracers for cancer imaging. Choline is a substrate for the synthesis of phosphati-dylcholine, which is a major phospholipid in the cell membrane. It has been hypothesized that uptake of radio-labeled Choline reflects proliferative activity by estimating membrane lipid synthesis. However, the exact uptake mechanism has to be established.
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© 2010 Springer-Verlag Berlin Heidelberg
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Farsad, M., Allegri, V., Castellucci, P. (2010). Choline PET-CT. In: Fanti, S., Farsad, M., Mansi, L. (eds) PET-CT Beyond FDG A Quick Guide to Image Interpretation. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-93909-2_3
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DOI: https://doi.org/10.1007/978-3-540-93909-2_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-93908-5
Online ISBN: 978-3-540-93909-2
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