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Osteonecrosis

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Abstract

Osteonecrosis is a condition of bone death leading to joint pain, bone destruction, and loss of function. Nontraumatic osteonecrosis, a disease entity in which the underlying etiology and pathogenesis have not been fully elucidated, commonly involves the femoral heads. Although a wide spectrum of conditions, including systemic steroid administration, that are potentially related to nontraumatic osteonecrosis of the femoral head (ONFH) have been reported so far, alcohol consumption continues to be important as an environmental factor. In this chapter, we present a summary of the descriptive and analytic epidemiology regarding alcohol-induced ONFH, as well as related issues including potential mechanisms for disease etiology and influences of alcohol-associated factors.

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Notes

  1. 1.

    Note: If patients with posttraumatic osteonecrosis of the femoral head were included in the study, the authors excluded the subjects and recalculated the proportion of alcohol-induced ONFH patients (hips) among all patients (hips).

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Authors and Affiliations

  1. Department of Public Health, Osaka City University Faculty of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan

    Wakaba Fukushima & Yoshio Hirota

Authors
  1. Wakaba Fukushima
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  2. Yoshio Hirota
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Correspondence to Wakaba Fukushima .

Editor information

Editors and Affiliations

  1. Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Kyonggi-do, Korea, Republic of (South Korea)

    Kyung-Hoi Koo

  2. Rubin Institute for Advanced Orthopedics, Center for Joint Preservation and Replacement, Sinai Hospital of Baltimore, Baltimore, Maryland, USA

    Michael A. Mont

  3. Department of Orthopaedic Surgery, Department of Orthopaedic Surgery, Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Lynne C. Jones

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© 2014 Springer-Verlag Berlin Heidelberg

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Fukushima, W., Hirota, Y. (2014). Alcohol. In: Koo, KH., Mont, M., Jones, L. (eds) Osteonecrosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35767-1_13

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  • DOI: https://doi.org/10.1007/978-3-642-35767-1_13

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  • Print ISBN: 978-3-642-35766-4

  • Online ISBN: 978-3-642-35767-1

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