Abstract
Since the work of Jack Burke (1961), it has been clearly established that true prophylaxis in surgical patients means preoperative administration of the prophylactic agent in such a way that all tissues encountered during surgery will have a therapeutic level of the agent present. This clearly means that true prophylaxis can only be applied in elective surgery or — with regard to fractures — when deciding to operate on a closed fracture.
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© 1992 Springer-Verlag Berlin Heidelberg
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Willenegger, H. (1992). Infections. In: Allgöwer, M. (eds) Manual of INTERNAL FIXATION. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77380-8_19
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DOI: https://doi.org/10.1007/978-3-642-77380-8_19
Publisher Name: Springer, Berlin, Heidelberg
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