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Urothelial Tumors

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Oncologic Imaging: Urology
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Abstract

Primary bladder neoplasms consist 2–6 % of all tumors, and bladder cancer is the fourth common malignancy [1]. Tumors can arise from the urothelium or other layers of the bladder wall. The bladder wall consists of four layers. The first layer is the uroepithelium. This consists of 3–7 layers of stratified flat cells. More superficial cells are flexible and change shape from cuboidal to flat with distension of the bladder. This is why we call it “transitional epithelium.” The second layer is the lamina propria. The third layer is the muscularis propria (detrusor muscle). The fourth layer is the adventitia. Bladder neoplasms arise from any of the four layers. They are classified into epithelial and nonepithelial tumors [1]. Epithelial tumors consist 95 % of bladder tumors. When epithelial tumor differentiates to normal urothelium, we call it urothelial. Other epithelial tumors include squamous cell carcinoma, adenocarcinoma, small cell/neuroendocrine carcinoma, carcinoid, and melanoma. These epithelial tumors occur at the surface of bladder lumen and usually show irregular, intraluminal mass.

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Choi, H.J., Moon, K.C., Kim, J.H., Ku, J.H. (2017). Urothelial Tumors. In: Kim, S., Cho, J. (eds) Oncologic Imaging: Urology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45218-9_2

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