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The Role of SDD in Liver Transplantation: a Meta-Analysis

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Selective Digestive Tract Decontamination in Intensive Care Medicine: a Practical Guide to Controlling Infection

Abstract

Wiesner et al. introduced SDD as infection prophylaxis in liver transplantation in 1987 and 1988 [1, 2]. These investigators reasoned that liver transplant recipients are the prime subset of patients to benefit from SDD prophylaxis for three reasons:

  1. 1.

    Liver transplant recipients are at high risk of infection

  2. 2.

    Most infections are endogenous following gut overgrowth

  3. 3.

    The potential pathogens causing infection in liver transplant recipients are aerobic Gram-negative bacilli (AGNB) and yeasts, the target microorganisms of SDD.

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Author information

Authors and Affiliations

  1. Department of Intensive Care, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands

    Peter H. J. van der Voort MD, PhD, MSc (Internist-intensivist)

  2. Department of Clinical Microbiology and Infection Control, Royal Liverpool Children’s NHS Trust of Alder Hey, Liverpool, UK

    Hendrick K. F. van Saene MD, PhD

Authors
  1. Peter H. J. van der Voort MD, PhD, MSc
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  2. Hendrick K. F. van Saene MD, PhD
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Editor information

Editors and Affiliations

  1. Department of Intensive Care, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands

    Peter H. J. van der Voort (Internist-intensivist) (Internist-intensivist)

  2. Department of Clinical Microbiology and Infection Control, Royal Liverpool Children’s NHS Trust of Alder Hey, Liverpool, UK

    Hendrick K. F. van Saene

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© 2008 Springer

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van der Voort, P.H.J., van Saene, H.K.F. (2008). The Role of SDD in Liver Transplantation: a Meta-Analysis. In: van der Voort, P.H.J., van Saene, H.K.F. (eds) Selective Digestive Tract Decontamination in Intensive Care Medicine: a Practical Guide to Controlling Infection. Springer, Milano. https://doi.org/10.1007/978-88-470-0653-9_13

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  • DOI: https://doi.org/10.1007/978-88-470-0653-9_13

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0652-2

  • Online ISBN: 978-88-470-0653-9

  • eBook Packages: MedicineMedicine (R0)

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