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Übersichtsarbeit

Ätiologie und Verlauf kindlichen dissozialen Verhaltens - Risikofaktoren für die Entwicklung einer antisozialen Persönlichkeitsstörung

Published Online:https://doi.org/10.1024/1422-4917.34.2.101

Zusammenfassung:Gegenstand: Störungen des Sozialverhaltens gehören zu den häufigsten Erkrankungen in unserem Fachgebiet. Methode: Die an der Entstehung von Störungen des Sozialverhaltens wesentlich beteiligten biologischen und psychosozialen Faktoren sowie deren Interaktion werden in dieser Übersichtsarbeit dargestellt. Dabei wird speziell auf Veränderungen der autonomen Reagibilität eingegangen. Ergebnis: Bei den unterschiedlichen Entwicklungspfaden hin zu einer antisozialen Persönlichkeitsstörung kommt frühen Formen von Störungen des Sozialverhaltens und dem psychopathischen Subtyp eine besondere Aussagekraft zu. Schlussfolgerung: Es wird die Bedeutung einer frühzeitigen Förderung gefährdeter Kinder zur Vermeidung einer dissozialen Entwicklung herausgestellt.


Aetiology and life-course of conduct disorder in childhood: Risk factors for the development of an antisocial personality disorder

Summary:Objectives: Conduct disorders are among the most common disorders encountered in child and adolescent psychiatry. They represent a heterogeneous group of disorders, each with a different psychopathology and a different life-course. While antisocial behaviour is only transient in some children, others show increasing criminal behaviour and delinquency, and some even develop an antisocial personality disorder. Methods: This review presents substantial biological and psychosocial factors, as well as their interaction in the aetiology of conduct disorders. Changes in autonomic responsiveness are emphasized. Results: Especially young children with conduct problems seem to be at greater risk for persistent and more widespread antisocial behaviour. Some of these children have emotional disturbances similar to those of psychopathic individuals. Conclusions: In order to prevent a negative course of the disorder, the relevance of primary care for children at high risk for antisocial behaviour is emphasized. In this context, the application of psychophysiological methods might be useful, in order to identify these children at an early stage.

Literatur

  • Angold, A. , Costello, E. (2001). The epidemiology of disorders of conduct: nosological issues and comorbidity. In: J. M. Hill (Ed.), Conduct Disorders in Childhood and Adolescence (pp 126-168). Cambridge: University Press First citation in articleGoogle Scholar

  • Bassarath, L. (2001). Conduct disorder: a biopsychosocial review. Canadian Journal of Psychiatry, 46, 609– 616 First citation in articleCrossref MedlineGoogle Scholar

  • Bates, J. E. , Bayles, K. , Bennett, D. , Ridge, B. , Brown, M. (1991). Origins of externalizing behavior problems at eight years of age. In: D. Pepler, K. Rubin (Eds.), The development and treatment of childhood aggression (pp 93-120). Hillsdale: Lawrence Erlbaum First citation in articleGoogle Scholar

  • Blair, R. J. (2003). Neurobiological basis of psychopathy. British Journal of Psychiatry, 182, 5– 7 First citation in articleCrossref MedlineGoogle Scholar

  • Blair, R. J. , Budhani, S. , Colledge, E. , Scott, S. (2005). Deafness to fear in boys with psychopathic tendencies. Journal of Child Psychology and Psychiatry, 46, 327– 336 First citation in articleCrossref MedlineGoogle Scholar

  • Blanz, B. (2001). Biologische Grundlagen von SSV und von aggressivem Verhalten. In: A. Warnke, G. Adams, N. Beck (Eds.) Dissozialität: Eine Herausforderung für Kinder- und Jugendpsychiatrie, Kinder- und Jugendhilfe, Schule und Justiz (pp 31-48). Würzburg: Lohrer Selbsthilfe GmbH First citation in articleGoogle Scholar

  • Boyle, M. H. , Offord, D. R. , Racine, Y. A. , Szatmari, P. , Fleming, J. E. , Links, P. S. (1992). Predicting substance use in late adolescence: results from the Ontario Child Health Study follow-up. American Journal of Psychiatry, 149, 761– 767 First citation in articleCrossref MedlineGoogle Scholar

  • Brain, P. F. , Susmann, E. (1997). Hormonal aspects of aggression and violence. In: D. M. Stoff, J. D. Maser, J. Breiling (Eds.), Handbook of antisocial behaviour (pp 314-323). New York: Wiley First citation in articleGoogle Scholar

  • Brook, J. S. , Whiteman, M. , Finch, S. J. , Cohen, P (1996). Young adult drug use and delinquency: childhood antecedents and adolescent mediators. Journal of the American Acadamy of Child and Adolescent Psychiatry, 35, 1584– 1592 First citation in articleCrossref MedlineGoogle Scholar

  • Carey, G. , Goldman, D. (1997). The genetics of antisocial behavior. In: D. M. Stoff (Ed.), Handbook of antisocial behavior (pp 243-254). Wiley First citation in articleGoogle Scholar

  • Caspi, A. , McClay, J. , Moffitt, T. E. , Mill, J. , Martin, J. , Craig, I. W. , Taylor, A. , Poulton, R. (2002). Role of genotype in the cycle of violence in maltreated children. Science, 297, 851– 85 First citation in articleCrossref MedlineGoogle Scholar

  • Checkley, H. (1941). The mask of sanity. St. Louis: Mosby First citation in articleGoogle Scholar

  • Christian, R. E. , Frick, P. J. , Hill, N. L. , Tyler, L. , Frazer, D. R. (1997). Psychopathy and conduct problems in children: II. Implications for subtyping children with conduct problems. Journal of the American Acadamy of Child and Adolescent Psychiatry,, 36, 233– 241 First citation in articleCrossref MedlineGoogle Scholar

  • Cjte, S. , Zoccolillo, M. , Tremblay, R. E. , Nagin, D. , Vitaro, F. (2001). Predicting girls’ conduct disorder in adolescence from childhood trajectories of disruptive behaviors. Journal of the American Acadamy of Child and Adolescent Psychiatry, 40, 678– 684 First citation in articleCrossref MedlineGoogle Scholar

  • Cloninger, C. R. (1987). A systematic method for clinical description and classification of personality variants. A proposal. Archives of General Psychiatry, 44, 573– 588 First citation in articleCrossref MedlineGoogle Scholar

  • Dick, D. M. , Viken, R. J. , Kaprio, J. , Pulkkinen, L. , Rose, R. J. (2005). Understanding the covariation among childhood externalizing symptoms: genetic and environmental influences on conduct disorder, attention deficit hyperactivity disorder, and oppositional defiant disorder symptoms. Journal of Abnormal Child Psychology, 33, 219– 229 First citation in articleCrossref MedlineGoogle Scholar

  • Dilling, H. , Mombour, W. , Schmidt, H. , Schulte-Markwort, M. (1994). Internationale Klassifikation psychischer Störungen: ICD-10. Bern: Huber First citation in articleGoogle Scholar

  • Dolan, M. , Park, I (2002). The neuropsychology of antisocial personality disorder. Psychological Medicine, 32, 417– 427 First citation in articleCrossref MedlineGoogle Scholar

  • Dolan, M. , Fullam, R. (2004). Theory of mind and mentalizing ability in antisocial personality disorders with and without psychopathy. Psychological Medicine, 34, 1093– 102 First citation in articleCrossref MedlineGoogle Scholar

  • Ernst, M. , Moolchan, E. T. , Robinson, M. L. (2001). Behavioral and neural consequences of prenatal exposure to nicotine. Journal of the American Acadamy of Child and Adolescent Psychiatry, 40, 630– 641 First citation in articleCrossref MedlineGoogle Scholar

  • Farrington, D. , Loeber, R. (1990). Longterm criminal outcomes of hyperactivity-impulsivity-attention deficit and conduct problems in childhood. In: L. Robins, M. Rutter M (Eds.), Straight and Devious Pathways from Childhood to Adulthood. Cambridge: University Press First citation in articleGoogle Scholar

  • Foley, D. L. , Eaves, L. J. , Wormley, B. , Silberg, J. L. , Maes, H.H. , Kuhn, J. , Riley, B. (2004). Childhood adversity, mono-amine oxidase a genotype, and risk for conduct disorder. Archives of General Psychiatry, 61, 738– 44 First citation in articleCrossref MedlineGoogle Scholar

  • Fowles, D. C. (1988). Psychophysiology and Psychopathology - A Motivational Approach. Psychophysiology, 25, 373– 391 First citation in articleCrossref MedlineGoogle Scholar

  • Frick, P. (1998). Conduct disorder and serve anisocial behavoir. New York: Plenum First citation in articleCrossrefGoogle Scholar

  • Fung, M. T. , Raine, A. , Loeber, R. , Lynam, D. R. , Steinhauer, S. R. , Venables, P. H. , Stouthamer-Loeber, M. (2005). Reduced electrodermal activity in psychopathy-prone adolescents. Journal of Abnormal Psychology, 114, 187– 196 First citation in articleCrossref MedlineGoogle Scholar

  • Gray, J. A. (1975). Elements of a two-process theory of learning. New York: Academic Press First citation in articleGoogle Scholar

  • Gray, J. A. , Owen, S. , Davis, N. , Tsaltas, E. (1983). Psychological and physiolgical relations between anxiety and impulsivity. In: A. Zuckerman (Ed.), The biological bases of sensation seeking, impulsivity, and anxiety (pp 181-227). Hillsdale First citation in articleGoogle Scholar

  • Haberstick, B. C. , Lessem, J. M. , Hopfer, C. J. , Smolen, A. , Ehringer, M. A. , Timberlake, D. , Hewitt, J. K. (2005). Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment. American Journal of Medical genetics. Part B.. Neuropsychiatric genetics, 135, 59– 64 First citation in articleCrossrefGoogle Scholar

  • Herbst, J. H. , Zonderman, A. B. , McCrae, R. R. , Costa, P. T. Jr. (200). Do the dimensions of the temperament and character inventory map a simple genetic architecture? Evidence from molecular genetics and factor analysis. American Journal of Psychiatry, 157, 1285– 1290 First citation in articleCrossrefGoogle Scholar

  • Herpertz, S. C. , Saß, H. (2000). Emotional deficiency and psychopathy. Behavioral Sciences & the Law, 18, 567– 580 First citation in articleCrossref MedlineGoogle Scholar

  • Herpertz, S. C. , Wenning, B. , Müller, B. , Qunaibi, M. , Saß, H. , Herpertz-Dahlmann, B. (2001a). Psychophysiological responses in ADHD boys with and without conduct disorder: implications for adult antisocial behavior. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 1222– 1230 First citation in articleCrossref MedlineGoogle Scholar

  • Herpertz, S. C. , Werth, U. , Lukas, G. , Qunaibi, M. , Schuerkens, A. , Kunert, H. J. , Freese, R. , Flesch, M. , Mueller-Isberner, R. , Osterheider, M. , Saß, H. (2001b). Emotion in criminal offenders with psychopathy and borderline personality disorder. Archives of General Psychiatry, 58, 737– 745 First citation in articleCrossref MedlineGoogle Scholar

  • Herpertz, S. C. , Müller, B. , Wenning, B. , Qunaibi, M. , Lichterfeld, C. , Herpertz-Dahlmann, B. (2003). Autonomic responses in boys with externalizing disorders. Journal of Neural Transmission, 110, 1181– 1195 First citation in articleCrossref MedlineGoogle Scholar

  • Herpertz, S. C. , Müller, B. , Qunaibi, M. , Lichterfeld, C. , Konrad, K. , Herpertz-Dahlmann, B. (2005). Response to emotional stimuli in boys with conduct disorder. American Journal of Psychiatry, 162, 100– 1107 First citation in articleCrossrefGoogle Scholar

  • Herpertz-Dahlmann, B. (2005). Dissozialität, Delinquenz und Verwahrlosung. In: H. Remschmidt (Ed.), Psychotherapie im Kindes- und Jugendalter (4th edition, pp 307-325). Stuttgart: Thieme First citation in articleGoogle Scholar

  • Herpertz-Dahlmann, B. , Herpertz, S. C. Persönlichkeitsstörungen. In: B. Herpertz-Dahlmann, F. Resch, M. Schulte-Markwort, A. Warnke (Eds.), Entwicklungspsychiatrie. Stuttgart: Schattauer; im Druck First citation in articleGoogle Scholar

  • Hicks, B. M. , Krueger, R. F. , Iacono, W. G. , McGue, M. , Patrick, C. J. (2004). Family transmission and heritability of externalizing disorders: a twin-family study. Archives of General Psychiatry, 61, 922– 928 First citation in articleCrossref MedlineGoogle Scholar

  • Hill, J. (2002). Biological, psychological and social processes in the conduct disorders. Journal of Child Psychology and Psychiatry, 43, 133– 164 First citation in articleCrossref MedlineGoogle Scholar

  • Intrator, J. , Hare, R. , Stritzke, P. , Brichtswein, K. , Dorfman, D. , Harpur, T. , Bernstein, D. , Handelsman, L. , Schaefer, C. , Keilp, J. , Rosen, J. , Machac, J. (1997). A brain imaging (single photon emission computerized tomography) study of semantic and affective processing in psychopaths. Biological Psychiatry, 42, 96– 103 First citation in articleCrossref MedlineGoogle Scholar

  • Kazdin, A. E. (1996). Conduct Disorders in Childhood and Adolescence. In: Developmental clinical psychology and psychiatry (2nd edition). Sage: Thousand Oaks First citation in articleGoogle Scholar

  • Keenan, K. , Loeber, R. , Green, S. (1999). Conduct disorder in girls: a review of the literature. Clinical Child and Family Psychology Review, 2, 3– 19 First citation in articleCrossref MedlineGoogle Scholar

  • Kerr, M. , Tremblay, R. E. , Pagani, L. , Vitaro, F. (1997). Boys’ behavioral inhibition and the risk of later delinquency. Archives of General Psychiatry, 5, 809– 816 First citation in articleCrossrefGoogle Scholar

  • Kessler, R. C. , Berglund, P. A. , Foster, C. L. , Saunders, W. B. , Stang, P. E. , Walters, E. E. (199). Social consequences of psychiatric disorders, II: Teenage parenthood. American Journal of Psychiatry, 154, 1405– 1411 First citation in articleGoogle Scholar

  • Kiehl, K. A. , Smith, A. M. , Hare, R. D. , Mendrek, A. , Forster, B. B. , Brink, J. , Liddle, P. F. (2001). Abnormalities in affective processing by criminal psychopaths as revealed by functional resonance imaging. Biological Psychiatry, 50, 677– 684 First citation in articleCrossref MedlineGoogle Scholar

  • Kruesi, M. J. , Casanova, M. F. , Mannheim, G. , Johnson-Bilder, A. (2004). Reduced temporal lobe volume in early onset conduct disorder. Psychiatry Research, 132, 1– 11 First citation in articleCrossref MedlineGoogle Scholar

  • Lahey, B. B. , Waldman, I. D. , McBurnett, K. (1999). Annotation: the development of antisocial behavior: an integrative causal model. Journal of Child Psychology and Psychiatry, 40, 669– 682 First citation in articleCrossref MedlineGoogle Scholar

  • Lahey, B. B. , McBurnett, K. , Loeber, R. (2000). Are attention-deficit/hyperactivity disorder and oppositional defiant disorder developmental precursors to conduct disorder?. In: A. J. Sameroff, M. Lewis, S. M. Miller (Eds.), Handbook of developmental psychopathology (pp 431-446). New York: Kluwer Academic/Plenum First citation in articleCrossrefGoogle Scholar

  • Langbehn, D. R. , Cadoret, R. J. (2001). The adult antisocial syndrome with and without antecedent conduct disorder: Comparisons from an adoption study. Comprehensive Psychiatry, 42, 272– 282 First citation in articleCrossref MedlineGoogle Scholar

  • Laucht, M. (2001). Antisoziales Verhalten im Jugendalter: Entstehungsbedingungen und Verlaufsformen. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 29, 297– 311 First citation in articleLinkGoogle Scholar

  • Laucht, M. , Schmidt, M. H. (2004). Mütterliches Rauchen in der Schwangerschaft: Risikofaktoren für eine ADHS des Kindes?. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 3, 177– 186 First citation in articleLinkGoogle Scholar

  • Loeber, R. (1990). Development and risk factors of juvenile antisocial behavior and delinquency. Clinical Psychology Review, 10, 1– 41 First citation in articleCrossrefGoogle Scholar

  • Loeber, R. , Burke, J. D. , Lahey, B. B. , Winters, A. , Zera, M. (2000). Oppositional defiant and conduct disorder: A review of the past 10 years, part I. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 1468– 1484 First citation in articleCrossref MedlineGoogle Scholar

  • Loney, B. R. , Frick, P. J. , Clements, C. B. , Ellis, M. L. , Kerlin, K. (200). Callous-unemotional traits, impulsivity, and emotional processing in adolescents with antisocial behavior problems. Journal of Clinical and Adolescent Psychology, 32, 66– 80 First citation in articleCrossrefGoogle Scholar

  • Lorber, M. F. (2004). Psychophysiology of aggression, psychopathy, and conduct problems: a meta-analysis. Psychological Bulletin, 130, 531– 552 First citation in articleCrossref MedlineGoogle Scholar

  • Lösel, F. , Bliesener, T. , Averbeck, M. (1999). Hat die Delinquenz von Schülern zugenommen? Ein Vergleich im Dunkelfeld nach 22 Jahren. In: M. Schäfer, D. Frey (Eds.), Aggression und Gewalt unter Kindern und Jugendlichen (pp 65-89). Göttingen: Hogrefe First citation in articleGoogle Scholar

  • Mannuzza, S. , Klein, R. G. , Abikoff, H. , Moulton, J. L. (2004). ignificance of childhood conduct problems to later development of conduct disorder among children with ADHD: a prospective follow-up study. Journal of abnormal Child Psychology, 32, 565– 573 First citation in articleCrossref MedlineGoogle Scholar

  • Matthys, W. , Egeland, H. , Resch, F (2003). SSV. In: B. Herpertz-Dahlmann, F. Resch, M. Schulte-Markwort, A. Warnke (Eds.), Entwicklungspsychiatrie (pp 754-773). Stuttgart: Schattauer First citation in articleGoogle Scholar

  • Matthys, W. , van Goozen, S. , de Vries, H. , Cohen-Kettenis, P. T. , van Engeland, H. (1998). The dominance of behavioural activation over behavioural inhibition in conduct disordered boys with or without attention deficit hyperactivity disorder. Journal of Child Psychology and Psychiatry and Allied Disciplines, 39, 643– 651 First citation in articleCrossref MedlineGoogle Scholar

  • Maughan, B. , Taylor, C. , Taylor, A. , Butler, N. , Bynner, J. (2001). Pregnancy smoking and childhood conduct problems: a causal association?. Journal of Child Psychology and Psychiatry, 42, 1021– 1028 First citation in articleCrossref MedlineGoogle Scholar

  • McCabe, K. M. , Hough, R. , Wood, P. A. , Yeh, M. (2001). Childhood and adolescent onset conduct disorder: a test of the developmental taxonomy. Journal of abnormal Child Psychology, 29, 305– 316 First citation in articleCrossref MedlineGoogle Scholar

  • McCloskey, M. S. , Luan Phan, K. , Coccaro, E. F. (2005). Neuroimaging and Personality Disorders. Neuroimaging and personality disorders. Current Psychiatry Reports, 7, 65– 72 First citation in articleGoogle Scholar

  • Mezzacappa, E. , Tremblay, R. E. , Kindlon, D. , Saul, J. P. , Arseneault, L. , Seguin, J. , Pihl, R. O. , Earls, F. (1997). Anxiety, antisocial behavior, and heart rate regulation in adolescent males. Journal of Child Psychology and Psychiatry, 38, 457– 469 First citation in articleCrossref MedlineGoogle Scholar

  • Milberger, S. , Biederman, J. , Faraone, S. V. , Chen, L. , Jones, J. (1996). Is maternal smoking during pregnancy a risk factor for attention deficit hyperactivity disorder in children?. American Journal of Psychiatry, 153, 1138– 1142 First citation in articleCrossref MedlineGoogle Scholar

  • Moffitt, T. E. (1993). Adolescence-limited and life-course-persistent antisocial behavior: a developmental taxonomy. Psychological Review, 100, 674– 701 First citation in articleCrossref MedlineGoogle Scholar

  • Moffitt, T. E. (1996). Childhood-onset versus adolescent-onset antisocial conduct in males: Natural history from age 3 to 18. Development and psychopathology, 8, 399– 424 First citation in articleCrossrefGoogle Scholar

  • Moffitt, T. E. , Caspi, A. (2001). Childhood predictors differentiate life-course persistent and adolescence-limited antisocial pathways among males and females. Development and psychopathology, 13, 355– 375 First citation in articleCrossref MedlineGoogle Scholar

  • Moffitt, T. E. , Caspi, A. , Harrington, H. , Milne, B. J. (2002). Males on the life-course-persistent and adolescence-limited antisocial pathways: follow-up at age 26 years. Development and psychopathology, 14, 179– 207 First citation in articleCrossref MedlineGoogle Scholar

  • Muller, J. I. , Sommer, M. , Wagner, V. , Lange, K. , Taschler, H. , Roder, C. H. , Schuierer, G. , Klein, H. E. , Hajak, G. (200). Abnormalities in emotion processing within cortical and subcortical regions in criminal psychopaths: evidence from a functional magnetic resonance imaging study using pictures with emotional content. Biological Psychiatry, 54, 152– 162 First citation in articleCrossrefGoogle Scholar

  • Müller-Isberner, R. , Eucker, S. , Herpertz, S. C. (2003). Dissoziale Persönlichkeitsstörung. In: S. Herpertz, H. Saß (Eds.), Persönlichkeitsstörungen (pp 71-76). Stuttgart: Thieme First citation in articleGoogle Scholar

  • Nagin, D. , Farrington, D. , Moffit, T. (1995). Life-course trajectories of different types of offender. Criminology, 29, 190– First citation in articleGoogle Scholar

  • Petermann, F. , Warschburger, P. (1998). Aggression. In: F. Perermann (Ed.), Lehrbuch der klinischen Kinderpsychologie (pp127-163). Göttingen: Hogrefe First citation in articleGoogle Scholar

  • Petras, H. , Schaeffer, C. M. , Ialongo, N. , Hubbard, S. , Muthen, B. , Lambert, S. F. , Poduska, J. , Kellam, S (2004). When the course of aggressive behavior in childhood does not predict antisocial outcomes in adolescence and young adulthood: an examination of potential explanatory variables. Developmental and Psychopathology, 16, 919– 941 First citation in articleCrossref MedlineGoogle Scholar

  • Pietrini, P. , Guazzelli, M. , Basso, G. , Jaffe, K. , Grafman, J. (2000). Neural correlates of imaginal aggressive behavior assessed by positron emission tomography in healthy subjects. American Journal of Psychiatry, 157, 1772– 1781 First citation in articleCrossref MedlineGoogle Scholar

  • Pliszka, S. , Carlson, C. L. , Swanson, J. M. (1999). ADHD with comorbid disorders. Clinical assessment and management. New York: Guilford Press First citation in articleGoogle Scholar

  • Quay, H. C. (1997). Inhibition and attention deficit hyperactivity disorder. Journal of Abnormal Child Psychology, 2, 7– 13 First citation in articleCrossrefGoogle Scholar

  • Raine, A. , Venables, P. H. , Williams, M. (1990). Relationships between central and autonomic measures of arousal at age 15 years and criminality at age 24 years. Archives of General Psychiatry, 47, 1003– 1007 First citation in articleCrossref MedlineGoogle Scholar

  • Raine, A. (1993). Criminal Behavior as a Clinical Disorder. In: The Psychopathology of Crime. San Diego: Academic Press First citation in articleGoogle Scholar

  • Raine, A. , Brennan, P. , Mednick, S. A. (1994). Birth complications combined with early maternal rejection at age 1 year predispose to violent crime at age 18 years. Archives of General Psychiatry, 5, 984– 988 First citation in articleCrossrefGoogle Scholar

  • Raine, A. , Venables, P. H. , Mednick, S. A. (1997). Low resting heart rate at age 3 years predisposes to aggression at age 11 years: evidence from the Mauritius Child Health Project. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 1457– 1464 First citation in articleCrossref MedlineGoogle Scholar

  • Raine, A. , Reynolds, C. , Venables, P. H. , Mednick, S. A. , Farrington, D. P. (1998). Fearlessness, stimulation-seeking, and large body size at age 3 years as early predispositions to childhood aggression at age 11 years. Archives of General Psychiatry, 5, 745– 751 First citation in articleCrossrefGoogle Scholar

  • Raine, A. , Lencz, T. , Bihrle, S. , LaCasse, L. , Colletti, P. (2000). Reduced prefrontal grey matter volume and reduced autonomic activity in antisocial personality disorder. Archives of General Psychiatry, 57, 119– 127 First citation in articleCrossref MedlineGoogle Scholar

  • Raine, A. , Venables, P. H. , Dalais, C. , Mellingen, K. , Reynolds, C. , Mednick, S. A. (2001). Early educational and health enrichment at age 3-5 years is associated with increased autonomic and central nervous system arousal and orienting at age 11 years: evidence from the Mauritius Child Health Project. Psychophysiology, 38, 254– 266 First citation in articleCrossref MedlineGoogle Scholar

  • Raine, A. , Moffitt, T. E. , Caspi, A. , Loeber, R. , Stouthamer-Loeber, M. , Lynam, D. (2005). Neurocognitive impairments in boys on the life-course persistent antisocial path. Journal of Abnormal Psychology, 114, 38– 49 First citation in articleCrossref MedlineGoogle Scholar

  • Resch, F. , Möhler, E. (2001). Wie entwickelt sich die kindliche Persönlichkeit? Beiträge zur Disskussion um Vererbung und Umwelt. In: M. Wink (Ed.) Vererbung und Milieu - Heidelberger Jahrbücher XLV (pp 95-151). Heidelberg: Springer First citation in articleGoogle Scholar

  • Richell, R. A. , Michell, D. G. , Newman, C. , Leonard, A. , Baron-Cohen, S. , Blair, R. J. (2003). Theory of mind and psychopathy: can psychopathic individuals read the «language of eyes»?. Neuropsychologia, 41, 523– 526 First citation in articleCrossref MedlineGoogle Scholar

  • Riggs, P. (1995). Adolescent substance abuse disorder with conduct disorder and other comorbid conditions. Institute Outline at the 42nd Annual Meeting of the American Academy of Child and Adolescent Psychiatry, First citation in articleGoogle Scholar

  • Robins, L. N. (1991). Conduct disorder. Journal of Child Psychology and Psychiatry. 32, 493– 512 First citation in articleGoogle Scholar

  • Rowe, R. , Maughan, B. , Worthman, C. M. , Costello, E. J. , Angold, A. (2004). Testosterone, antisocial behavior, and social dominance in boys: pubertal development and biosocial interaction. Biological Psychiatry, 55, 546– 552 First citation in articleCrossref MedlineGoogle Scholar

  • Rutter, M. , Giller, A , Hagel, A. (1998). Antisocial behavior by young people. Cambridge: University Press First citation in articleGoogle Scholar

  • Rutter, M. (2005). Enviromentally mediated risks for psychopathology: research strategies and findings. Journal of the American Academy of Child and Adolescent Psychiatry, 44, 3– 18 First citation in articleCrossref MedlineGoogle Scholar

  • Salekin, R. T. (2005). Psychopathy in children and adolescents: the need for a developmental perspective. Journal of Abnormal Child Psychology, 33, 403– 409 First citation in articleCrossref MedlineGoogle Scholar

  • Saß, H. , Wittchen, H. , Zaudig, M. (1996). Diagnostisches und statistisches Manual psychischer Störungen. DSM-IV. Göttingen: Hogrefe First citation in articleGoogle Scholar

  • Scarpa, A. , Raine, A. (2004). The psychophysiology of child misconduct. Pediatric Annals, 33, 296– 304 First citation in articleCrossref MedlineGoogle Scholar

  • Schmeck, K. , Poustka, F. (2000). Biologische Grundlagen von impulsiv-aggresivem Verhalten. Kindheit und Entwicklung, 9, 3– 13 First citation in articleLinkGoogle Scholar

  • Sevecke, K. , Krischer, M. K. , Döpfner, M. , Lehmkuhl, G. (2005). Das Psychopathy-Konzept und seine psychometrische Erfassung im Kindes-, Jugend- und Erwachsenenalter. Fortschritte der Neurologie-Psychiatrie, 73, 392– 400 First citation in articleCrossref MedlineGoogle Scholar

  • Simonoff, E. , Elander, J. , Holmshaw, J. , Pickles, A. , Murray, R. , Rutter, M. (2004). Predictors of antisocial personality. Continuities from childhood to adult life. British Journal of Psychiatry, 184, 118– 127 First citation in articleCrossref MedlineGoogle Scholar

  • Skilling, T. A. , Harris, G. T. , Rice, M. E. (2002). Identifing persistently antisocial offenders using the Hare pyschopathy checklist and DSM antisocial personality disorder criteria. Psychological Assessment, 14, 27– 38 First citation in articleCrossref MedlineGoogle Scholar

  • Slutske, W. S. , Heath, A. C. , Dinwiddie, S. H. , Madden, P. A. F. , Bucholz, K. K. , Dunne, M. P. , Statham, D. J. , Martin, N.G. (1997). Modeling genetic and environmental influences in the etiology of conduct disorder: a study of 2,682 adult twin pairs. Journal of Abnormal Psychology, 106, 266– 279 First citation in articleCrossref MedlineGoogle Scholar

  • Smith, C. A. , Farrington, D. P. (2004). Continuities in antisocial behavior and parenting across three generations. Journal of Child Psychology and Psychiatry, 45, 230– 247 First citation in articleCrossref MedlineGoogle Scholar

  • Soderstrom, H. , Sjodin, A. K. , Carlstedt, A. , Forsman, A. (2004). Adult psychopathic personality with childhood-onset hyperactivity and conduct disorder: a central problem constellation in forensic psychiatry. Psychiatry Research, 121, 271– 280 First citation in articleCrossref MedlineGoogle Scholar

  • Steiner, H. (1997). Practice parameters for the assessment and treatment of children and adolescents with conduct disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 36, 122– 139 First citation in articleCrossrefGoogle Scholar

  • Sterzer, P. , Stadler, C. , Krebs, A. , Kleinschmidt, A. , Poustka, F. (2005). Abnormal neural responses to emotional visual stimuli in adolescents with conduct disorder. Biological Psychiatry, 57, 7– 15 First citation in articleCrossref MedlineGoogle Scholar

  • Trautmann-Villalba, P. , Gerhold, M. , Polowczyk, M. , Dinter-Jorg, M. , Laucht, M. , Esser, G. , Schmidt, M. H. (2001). Mutter-Kind Interaktion und externalisierende Störungen bei Grundschulkindern. Zeitschrift für Kinder und Jugendpsychiatrie und Psychotherapie, 29, 263– 273 First citation in articleLinkGoogle Scholar

  • Upadhyaya, H. P. , Deas, D. , Brady, K. T. , Kruesi, M. (2002). Cigarette smoking and psychiatric comorbidity in children and adolescents. Journal of the American Acadamie of Child and Adolescent Psychiatry, 41, 1294– 1305 First citation in articleCrossref MedlineGoogle Scholar

  • Viding, E. , Blair, R. J. , Moffitt, T. E. , Plomin, R. (2005). Evidence for substantial genetic risk for psychopathy in 7-year-olds. Journal of Child Psychology and Psychiatry, 46, 592– 597 First citation in articleCrossref MedlineGoogle Scholar

  • van Bokhoven, I. , van Goozen, S. H. , van Engeland, H. , Schaal, B. , Arseneault, L. , Seguin, J. R. , Nagin, D. S. , Vitaro, F. , Tremblay, R. E. (2005). Salivary cortisol and aggression in a population-based longitudinal study of adolescent males. Journal of Neural Transmission, 112, 1083– 1096 First citation in articleCrossref MedlineGoogle Scholar

  • Vloet, T. D. (2006). Prädiktoren dissozialen Verhaltens-periphere psychophysiologische Befunde bei Kindern und Erwachsenen mit SSV. Nervenarzt, im Druck First citation in articleGoogle Scholar

  • Walter, R. , Remschmidt, H. (2004). Die Vorhersage der Delinquenz im Kindes-, Jugend- und Erwachsenenalter: Ergebnisse einer prospektiven Studie. Monatsschrift für Kriminologie und Strafrechtsreform, 87, 333– 352 First citation in articleCrossrefGoogle Scholar

  • Werner, E. E. , Smith, R. S. (1992). Overcoming in odds: high risk children from birth to adulthood. Ithaca, New York: Cornell University Press First citation in articleGoogle Scholar

  • Werner, E. E. , Smith, R. S. (2001). Journeys from childhood to midlife: risk, resilience and recovery. Ithaca, New York: Cornell University Press First citation in articleGoogle Scholar

  • Zimmerman, M. , Arunkumar, R. (1994). Resiliency research: implications for schools and policy. Social Policy Report, Society for research in child development, Ann Arbor First citation in articleGoogle Scholar