Skip to main content
Full-Length Research Report

Psychological Effects of Social Isolation During the COVID-19 Pandemic 2020

Published Online:https://doi.org/10.1024/1662-9647/a000283

Abstract. The SARS-CoV2 pandemic meant considerable restrictions in the social life of many people. Older people belong to the high-risk group for a severe to fatal course of the SARS-CoV2 disease, which is why these groups received special protection. This protection included drastic restrictions on their personal and social contacts, including the suspension of psychosocial therapies. This study examines the cognitive and emotional effects of social isolation on older people. A group of 49 participants who lived in nursing homes was tested before and after social isolation in 2020. The results of the present study provide empirical evidence for the negative effects of social isolation of older people in nursing homes regarding cognitive performance, anxiety, depressive symptoms, and quality of life.

References

  • Ahmed, M. Z., Ahmed, O., Aibao, Z., Hanbin, S., Siyu, L., & Ahmad, A. (2020). Epidemic of COVID-19 in China and associated psychological problems. Asian Journal of Psychiatry, 51, Article 102092. https://doi.org/10.1016/j.ajp.2020.102092 First citation in articleCrossrefGoogle Scholar

  • Austria, S. (2021). Bevölkerung nach Alter und Geschlecht [Population by age and gender]. Statistik Austria. http://pic.statistik.at/web_de/statistiken/menschen_und_gesellschaft/bevoelkerung/bevoelkerungsstruktur/bevoelkerung_nach_alter_geschlecht/031384.html First citation in articleGoogle Scholar

  • Bahr, H. M., Peplau, L. A., & Perlman, D. (1984). Loneliness: A sourcebook of current theory, research and therapy. Contemporary Sociology, 13(2), 203–204. https://doi.org/10.2307/2068915 First citation in articleCrossrefGoogle Scholar

  • Barak, Y., Gray, A. R., Rapsey, C., & Scott, K. (2019). The Dunedin dementia risk awareness project: Pilot study in older adults. International Psychogeriatrics, 32(2), 241–254. https://doi.org/10.1017/s1041610219000772 First citation in articleCrossrefGoogle Scholar

  • Beck, A. T., Epstein, N., Brown, G., & Steer, R. A. (1988). An inventory for measuring clinical anxiety: Psychometric properties. Journal of Consulting and Clinical Psychology, 56(6), 893–897. https://doi.org/10.1037/0022-006x.56.6.893 First citation in articleCrossrefGoogle Scholar

  • Bentur, N., & Heymann, A. D. (2020). Depressive symptoms and use of health services among older adults in Israel. Israel Journal of Health Policy Research, 9(1), 1–6. https://doi.org/10.1186/s13584-020-00374-5 First citation in articleCrossrefGoogle Scholar

  • Beyermann, S., Trippe, R., Bähr, A., & Püllen, R. (2013). Mini-Mental-Status-Test im stationären geriatrischen Bereich [Mini-Mental-Status-Test in the Geriatric Area]. Zeitschrift für Gerontologie und Geriatrie, 46(8), 740–747. https://doi.org/10.1007/s00391-013-0488-6 First citation in articleCrossrefGoogle Scholar

  • Bianchetti, A., Rozzini, R., Guerini, F., Boffelli, S., Ranieri, P., Minelli, G., Bianchetti, L., & Trabucchi, M. (2020). Clinical presentation of COVID19 in dementia patients. The Journal of Nutrition, Health & Aging, 24(6), 560–562. https://doi.org/10.1007/s12603-020-1389-1 First citation in articleCrossrefGoogle Scholar

  • Birditt, K. S., Turkelson, A., Fingerman, K. L., Polenick, C. A., & Oya, A. (2021). Age Differences in Stress, Life Changes, and Social Ties During the COVID-19 Pandemic: Implications for Psychological Well-Being. The Gerontologist, 61(2), 205–216. https://doi.org/10.1093/geront/gnaa204 First citation in articleCrossrefGoogle Scholar

  • Brakemeier, E. L., Wirkner, J., Knaevelsrud, C., Wurm, S., Christiansen, H., Lueken, U., & Schneider, S. (2020). Die COVID-19-Pandemie als Herausforderung für die psychische Gesundheit [The COVID-19 pandemic as a mental health challenge]. Zeitschrift für Klinische Psychologie und Psychotherapie, 49(1), 1–31. https://doi.org/10.1026/1616-3443/a000574 First citation in articleLinkGoogle Scholar

  • Cacioppo, S., Capitanio, J. P., & Cacioppo, J. T. (2014). Toward a neurology of loneliness. Psychological Bulletin, 140(6), 1464–1504. https://doi.org/10.1037/a0037618 First citation in articleCrossrefGoogle Scholar

  • Chow, E. S., Kong, B. M., Wong, M. T., Draper, B., Lin, K. L., Ho, S. K., & Wong, C. P. (2004). The prevalence of depressive symptoms among elderly Chinese private nursing-home residents in Hong Kong. International Journal of Geriatric Psychiatry, 19(8), 734–740. https://doi.org/10.1002/gps.1158 First citation in articleCrossrefGoogle Scholar

  • Cornwell, E. Y., & Waite, L. J. (2009). Social disconnectedness, perceived isolation, and health among older adults. Journal of Health and Social Behavior, 50(1), 31–48. https://doi.org/10.1177/002214650905000103 First citation in articleCrossrefGoogle Scholar

  • Courtin, E., & Knapp, M. (2017). Social isolation, loneliness and health in old age: A scoping review. Health & Social Care in the Community, 25(3), 799–812. https://doi.org/10.1111/hsc.12311 First citation in articleCrossrefGoogle Scholar

  • Covino, M., De Matteis, G., Santoro, M., Sabia, L., Simeoni, B., Candelli, M., Ojetti, V., & Franceschi, F. (2020). Clinical characteristics and prognostic factors in COVID-19 patients aged ≥ 80 years. Geriatrics & Gerontology International, 20(7), 704–708. https://doi.org/10.1111/ggi.13960 First citation in articleCrossrefGoogle Scholar

  • Coyle, C. E., & Dugan, E. (2012). Social isolation, loneliness and health among older adults. Journal of Aging and Health, 24(8), 1346–1363. https://doi.org/10.1177/0898264312460275 First citation in articleCrossrefGoogle Scholar

  • de Beurs, E., Wilson, K. A., Chambless, D. L., Goldstein, A. J., & Feske, U. (1997). Convergent and divergent validity of the Beck Anxiety Inventory for patients with panic disorder and agoraphobia. Depression and Anxiety, 6(4), 140–146. First citation in articleCrossrefGoogle Scholar

  • Dilling, H., & Freyberger, H. J. (2019). Taschenführer zur ICD-10-Klassifikation psychischer Störungen (9., akt. Auflage entsprechend ICD-10-GM) [Pocket Guide to the ICD-10 Classification of Mental Disorders]. Huber. First citation in articleCrossrefGoogle Scholar

  • Drageset, J., Eide, G. E., & Ranhoff, A. H. (2011). Depression is associated with poor functioning in activities of daily living among nursing-home residents without cognitive impairment. Journal of Clinical Nursing, 20(21–22), 3111–3118. https://doi.org/10.1111/j.1365-2702.2010.03663.x First citation in articleCrossrefGoogle Scholar

  • Drageset, J., Eide, G. E., & Ranhoff, A. H. (2013). Anxiety and depression among nursing-home residents without cognitive impairment. Scandinavian Journal of Caring Sciences, 27(4), 872–881. https://doi.org/10.1111/j.1471-6712.2012.01095.x First citation in articleCrossrefGoogle Scholar

  • Fahrenberg, J., Myrtek, M., Schumacher, J., & Brähler, E. (2000). Fragebogen zur Lebenszufriedenheit (FLZ). Handanweisung (1. Aufl.) [Life Satisfaction Questionnaire]. Hogrefe. First citation in articleGoogle Scholar

  • Flöer, C. (2021, Mai 10). MMST/MMSE, Mini-Mental-Status Test/State Examination. https://www.pflege.de/krankheiten/demenz/test/mmst/ First citation in articleGoogle Scholar

  • Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). Mini-mental state. Journal of Psychiatric Research, 12(3), 189–198. https://doi.org/10.1016/0022-3956(75)90026-6 First citation in articleCrossrefGoogle Scholar

  • Gauggel, S., & Birkner, B. (1999). Validität und Reliabilität einer deutschen Version der Geriatrischen Depressionsskala (GDS) [Validity and reliability of a German Version of the Geriatric Depression Scale]. Zeitschrift für Klinische Psychologie und Psychotherapie, 28(1), 18–27. https://doi.org/10.1026//0084-5345.28.1.18 First citation in articleLinkGoogle Scholar

  • Glaesmer, H., Riedel-Heller, S., Braehler, E., Spangenberg, L., & Luppa, M. (2011). Age- and gender-specific prevalence and risk factors for depressive symptoms in the elderly: A population-based study. International Psychogeriatrics, 23(8), 1294–1300. https://doi.org/10.1017/S1041610211000780 First citation in articleCrossrefGoogle Scholar

  • Grande, G., Vetrano, D. L., Cova, I., Pomati, S., Mattavelli, D., Maggiore, L., Cucumo, V., Ghiretti, R., Vanacore, N., Mariani, C., & Rizzuto, D. (2018). Living alone and dementia incidence: A clinical-based study in people with mild cognitive impairment. Journal of Geriatric Psychiatry and Neurology, 31(3), 107–113. https://doi.org/10.1177/0891988718774425 First citation in articleCrossrefGoogle Scholar

  • Hawkley, L. C., & Cacioppo, J. T. (2010). Loneliness matters: A theoretical and empirical review of consequences and mechanisms. Annals of Behavioral Medicine, 40(2), 218–227. https://doi.org/10.1007/s12160-010-9210-8 First citation in articleCrossrefGoogle Scholar

  • Herron, R. V., Newall, N., Lawrence, B. C., Ramsey, D., Waddell, C. M., & Dauphinais, J. (2021). Conversations in times of isolation: Exploring rural-dwelling older adults’ experiences of isolation and loneliness during the COVID-19 pandemic in Manitoba, Canada. International Journal of Environmental Research and Public Health, 18(6), Article 3028. https://doi.org/10.3390/ijerph18063028 First citation in articleCrossrefGoogle Scholar

  • Hozhabri, H., Piceci Sparascio, F., Sohrabi, H., Mousavifar, L., Roy, R., Scribano, D., De Luca, A., Ambrosi, C., & Sarshar, M. (2020). The global emergency of novel coronavirus (SARS-CoV-2): An update of the current status and forecasting. International Journal of Environmental Research and Public Health, 17(16), Article 5648. https://doi.org/10.3390/ijerph17165648 First citation in articleCrossrefGoogle Scholar

  • Hu, S. H., Chuang, Y. H., Ting, Y. F., Lin, K. Y., & Hsieh, C. J. (2018). Prevalence of depressive symptoms in older nursing-home residents with intact cognitive function in Taiwan. Research in Nursing & Health, 41(3), 292–300. https://doi.org/10.1002/nur.21873 First citation in articleCrossrefGoogle Scholar

  • JASP Team. (2019). JASP (Version 0.11.1) [Computer Software]. First citation in articleGoogle Scholar

  • Jiménez-Pavón, D., Carbonell-Baeza, A., & Lavie, C. J. (2020). Physical exercise as therapy to fight against the mental and physical consequences of COVID-19 quarantine: Special focus in older people. Progress in Cardiovascular Diseases, 63(3), 386–388. https://doi.org/10.1016/j.pcad.2020.03.009 First citation in articleCrossrefGoogle Scholar

  • Kramer, D., Allgaier, A. K., Fejtkova, S., Mergl, R., & Hegerl, U. (2009). Depression in nursing homes: Prevalence, recognition, and treatment. The International Journal of Psychiatry in Medicine, 39(4), 345–358. https://doi.org/10.2190/pm.39.4.a First citation in articleCrossrefGoogle Scholar

  • krone tv. (2020, March 13). Live Pressekonferenz: Sebastian Kurz zu den kommenden Maßnahmen [Sebastion Kurz on the upcoming measures]. https://www.youtube.com/watch?v=pH0u8ZKSfq0 First citation in articleGoogle Scholar

  • Lauth, G., & Viebahn, P. (1987). Soziale Isolierung: Ursachen und Interventionsmöglichkeiten [Social isolation: Causes and options for intervention]. Psychologie Verlags Union. First citation in articleGoogle Scholar

  • Licher, S., Ahmad, S., Karamujić-Čomić, H., Voortman, T., Leening, M. J. G., Ikram, M. A., & Ikram, M. K. (2019). Genetic predisposition, modifiable-risk-factor profile and long-term dementia risk in the general population. Nature Medicine, 25(9), 1364–1369. https://doi.org/10.1038/s41591-019-0547-7 First citation in articleCrossrefGoogle Scholar

  • Linden, M., Kurtz, G., Baltes, M. M., Geiselmann, B., Lang, F. R., Reischies, F. M., & Helmchen, H. (1998). Depression bei Hochbetagten [Depression in the very old]. Der Nervenarzt, 69(1), 27–37. https://doi.org/10.1007/s001150050235 First citation in articleCrossrefGoogle Scholar

  • Linden, M., Kurtz, G., Baltes, M. M., Geiselmann, B., Lang, F. R., Reischies, F. M., & Helmchen, H. (2018). Depression in old age. Results from the Berlin Aging Study. Der Nervenarzt, 69, 27–37. https://doi.org/10.1007/s001150020235 First citation in articleCrossrefGoogle Scholar

  • Lindesay, J. (1990). The guy’s/age concern survey: Physical health and psychiatric disorder in an urban elderly community. International Journal of Geriatric Psychiatry, 5(3), 171–178. https://doi.org/10.1002/gps.930050305 First citation in articleCrossrefGoogle Scholar

  • Liu, S., Yang, L., Zhang, C., Xiang, Y. T., Liu, Z., Hu, S., & Zhang, B. (2020). Online mental health services in China during the COVID-19 outbreak. The Lancet Psychiatry, 7(4), e17–e18. https://doi.org/10.1016/s2215-0366(20)30077-8 First citation in articleCrossrefGoogle Scholar

  • Luchetti, M., Terracciano, A., Aschwanden, D., Lee, J. H., Stephan, Y., & Sutin, A. R. (2020). Loneliness is associated with risk of cognitive impairment in the Survey of Health, Ageing and Retirement in Europe. International Journal of Geriatric Psychiatry, 35(7), 794–801. https://doi.org/10.1002/gps.5304 First citation in articleCrossrefGoogle Scholar

  • Luppa, M., Sikorski, C., Luck, T., Ehreke, L., Konnopka, A., Wiese, B., Weyerer, S., König, H. H., & Riedel-Heller, S. G. (2012). Age- and gender-specific prevalence of depression in latest-life: Systematic review and meta-analysis. Journal of Affective Disorders, 136(3), 212–221. https://doi.org/10.1016/j.jad.2010.11.033 First citation in articleCrossrefGoogle Scholar

  • Margraf, J., & Ehlers, A. (2007). Das Beck-Angstinventar (BAI) [The Fear Inventory]. Springer. First citation in articleGoogle Scholar

  • Mazza, C., Ricci, E., Biondi, S., Colasanti, M., Ferracuti, S., Napoli, C., & Roma, P. (2020). A nationwide survey of psychological distress among italian people during the COVID-19 pandemic: Immediate psychological responses and associated factors. International Journal of Environmental Research and Public Health, 17(9), Article 3165. https://doi.org/10.3390/ijerph17093165 First citation in articleCrossrefGoogle Scholar

  • McCracken, L. M., Badinlou, F., Buhrman, M., & Brocki, K. C. (2020). Psychological impact of COVID-19 in the Swedish population: Depression, anxiety, and insomnia and their associations to risk and vulnerability factors. European Psychiatry, 63(1), Article e81. https://doi.org/10.1192/j.eurpsy.2020.81 First citation in articleCrossrefGoogle Scholar

  • Mukhtar, S. (2020). Psychological health during the coronavirus disease 2019 pandemic outbreak. International Journal of Social Psychiatry, 66(5), 512–516. https://doi.org/10.1177/0020764020925835 First citation in articleCrossrefGoogle Scholar

  • Müller, F., Röhr, S., Reininghaus, U., & Riedel-Heller, S. G. (2021). Social isolation and loneliness during COVID-19 lockdown: Associations with depressive symptoms in the German old-age population. International Journal of Environmental Research and Public Health, 18(7), Article 3615. https://doi.org/10.3390/ijerph18073615 First citation in articleCrossrefGoogle Scholar

  • Nwachukwu, I., Nkire, N., Shalaby, R., Hrabok, M., Vuong, W., Gusnowski, A., Surood, S., Urichuk, L., Greenshaw, A. J., & Agyapong, V. I. (2020). COVID-19 pandemic: Age-related differences in measures of stress, anxiety and depression in Canada. International Journal of Environmental Research and Public Health, 17(17), Article 6366. https://doi.org/10.3390/ijerph17176366 First citation in articleCrossrefGoogle Scholar

  • O’Boyle, C. A., & Waldron, D. (1997). Quality of life issues in palliative medicine. Journal of Neurology, 244(S4), S18–S25. https://doi.org/10.1007/pl00007720 First citation in articleCrossrefGoogle Scholar

  • Olsen, C., Pedersen, I., Bergland, A., Enders-Slegers, M. J., Jøranson, N., Calogiuri, G., & Ihlebæk, C. (2016). Differences in quality of life in home-dwelling persons and nursing-home residents with dementia: A cross-sectional study. BMC Geriatrics, 16(1). https://doi.org/10.1186/s12877-016-0312-4 First citation in articleCrossrefGoogle Scholar

  • ORF.at. (2020, March 12). Coronavirus: Besuche in Altersheimen unerwünscht [Coronavirus: Visits to old people’s homes are undesirable]. https://tirol.orf.at/stories/3038778/ First citation in articleGoogle Scholar

  • Österreichische Alzheimer Gesellschaft. (2017, August 29). Zahlen & Statistik [Numbers & Statistics]. http://www.alzheimer-gesellschaft.at/informationen/zahlen-statistik/ First citation in articleGoogle Scholar

  • Pavot, W., Diener, E., Colvin, C. R., & Sandvik, E. (1991). Further validation of the Satisfaction With Life Scale: Evidence for the cross-method convergence of well-being measures. Journal of Personality Assessment, 57(1), 149–161. https://doi.org/10.1207/s15327752jpa5701_17 First citation in articleCrossrefGoogle Scholar

  • Perlman, D., & Peplau, L. (1982). Theoretical approaches to loneliness. In D. PerlmanL. A. PeplauEds., Loneliness: A sourcebook of current theory, research and therapy (pp. 123–134). Wiley Interscience. First citation in articleGoogle Scholar

  • Pieh, C., Budimir, S., & Probst, T. (2020). The effect of age, gender, income, work, and physical activity on mental health during coronavirus disease (COVID-19) lockdown in Austria. Journal of Psychosomatic Research, 136, Article 110186. https://doi.org/10.1016/j.jpsychores.2020.110186 First citation in articleCrossrefGoogle Scholar

  • Potter, C. (2001). A history of influenza. Journal of Applied Microbiology, 91(4), 572–579. https://doi.org/10.1046/j.1365-2672.2001.01492.x First citation in articleCrossrefGoogle Scholar

  • Rafnsson, S. B., Orrell, M., d'Orsi, E., Hogervorst, E., & Steptoe, A. (2020). Loneliness, social integration, and incident dementia over 6 years: prospective findings from the English longitudinal study of ageing. The Journals of Gerontology: Series B, Psychological Sciences and Social Sciences, 75(1), 114–124. https://doi.org/10.1093/geronb/gbx087 First citation in articleCrossrefGoogle Scholar

  • Rodda, J., Walker, Z., & Carter, J. (2011). Depression in older adults. BMJ (Clinical Research Ed.), 343, Article d5219. https://doi.org/10.1136/bmj.d5219 First citation in articleCrossrefGoogle Scholar

  • Shankar, A., Hamer, M., McMunn, A., & Steptoe, A. (2013). Social isolation and loneliness: Relationships with cognitive function during 4 years of follow-up in the English Longitudinal Study of Ageing. Psychosomatic Medicine, 75(2), 161–170. https://doi.org/10.1097/PSY.0b013e31827f09cd First citation in articleCrossrefGoogle Scholar

  • Solomou, I., & Constantinidou, F. (2020). Prevalence and predictors of anxiety and depression symptoms during the COVID-19 pandemic and compliance with precautionary measures: Age and sex matter. International Journal of Environmental Research and Public Health, 17(14), Article 4924. https://doi.org/10.3390/ijerph17144924 First citation in articleCrossrefGoogle Scholar

  • Sommerlad, A., Sabia, S., Singh-Manoux, A., Lewis, G., & Livingston, G. (2019). Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study. PLoS Medicine, 16(8), Article e1002862. https://doi.org/10.1371/journal.pmed.1002862 First citation in articleCrossrefGoogle Scholar

  • Stewart, R., Hotopf, M., Dewey, M., Ballard, C., Bisla, J., Calem, M., Fahmy, V., Hockley, J., Kinley, J., Pearce, H., Saraf, A., & Begum, A. (2014). Current prevalence of dementia, depression and behavioural problems in the older adult care home sector: The South East London Care Home Survey. Age and Ageing, 43(4), 562–567. https://doi.org/10.1093/ageing/afu062 First citation in articleCrossrefGoogle Scholar

  • Sundström, A., Adolfsson, A. N., Nordin, M., & Adolfsson, R. (2019). Loneliness increases the risk of all-cause dementia and Alzheimer’s disease. The Journals of Gerontology: Series B, 75(5), 919–926. https://doi.org/10.1093/geronb/gbz139 First citation in articleCrossrefGoogle Scholar

  • Tan, J. H., Abdin, E., Shahwan, S., Zhang, Y., Sambasivam, R., Vaingankar, J. A., Mahendran, R., Chua, H. C., Chong, S. A., & Subramaniam, M. (2019). Happiness and cognitive impairment among older adults: Investigating the mediational roles of disability, depression, social contact frequency, and loneliness. International Journal of Environmental Research and Public Health, 16(24), Article 4954. https://doi.org/10.3390/ijerph16244954 First citation in articleCrossrefGoogle Scholar

  • Taylor, H. O., Taylor, R. J., Nguyen, A. W., & Chatters, L. (2018). Social isolation, depression, and psychological distress among older adults. Journal of Aging and Health, 30(2), 229–246. https://doi.org/10.1177/0898264316673511 First citation in articleCrossrefGoogle Scholar

  • Wan, Y., Wu, J., Ni, L., Luo, Q., Yuan, C., Fan, F., Liu, H., Zhang, C., Xiang, Y., & Xie, Q. (2020). Prognosis analysis of patients with mental disorders with COVID-19: A single-center retrospective study. Aging, 12(12), 11238–11244. https://doi.org/10.18632/aging.103371 First citation in articleCrossrefGoogle Scholar

  • Wang, Y., Di, Y., Ye, J., & Wei, W. (2021). Study on the public psychological states and its related factors during the outbreak of coronavirus disease 2019 (COVID-19) in some regions of China. Psychology, Health & Medicine, 26(1), 13–22. https://doi.org/10.1080/13548506.2020.1746817 First citation in articleCrossrefGoogle Scholar

  • Weissman, M. M., Leaf, P. J., Tischler, G. L., Blazer, D. G., Karno, M., Bruce, M. L., & Florio, L. P. (1988). Affective disorders in five United States communities. Psychological Medicine, 18(1), 141–153. https://doi.org/10.1017/s0033291700001975 First citation in articleCrossrefGoogle Scholar

  • Wetherell, J. L., & Areán, P. A. (1997). Psychometric evaluation of the Beck Anxiety Inventory with older medical patients. Psychological Assessment, 9(2), 136–144. https://doi.org/10.1037/1040-3590.9.2.136 First citation in articleCrossrefGoogle Scholar

  • WHO. (2020, January 30). Depression. https://www.who.int/news-room/fact-heets/detail/depression First citation in articleGoogle Scholar

  • WHO. (2021, July 8). WHO coronavirus (COVID-19) dashboard. With vaccination data. https://covid19.who.int/ First citation in articleGoogle Scholar

  • Wolitzky-Taylor, K. B., Castriotta, N., Lenze, E. J., Stanley, M. A., & Craske, M. G. (2010). Anxiety disorders in older adults: A comprehensive review. Depression and Anxiety, 27(2), 190–211. https://doi.org/10.1002/da.20653 First citation in articleCrossrefGoogle Scholar

  • Yesavage, J. A., Brink, T., Rose, T. L., Lum, O., Huang, V., Adey, M., & Leirer, V. O. (1982). Development and validation of a geriatric depression screening scale: A preliminary report. Journal of Psychiatric Research, 17(1), 37–49. https://doi.org/10.1016/0022-3956(82)90033-4 First citation in articleCrossrefGoogle Scholar

  • Zhu, N., Zhang, D., Wang, W., Li, X., Yang, B., Song, J., Zhao, X., Huang, B., Shi, W., Lu, R., Niu, P., Zhan, F., Ma, X., Wang, D., Xu, W., Wu, G., Gao, G. F., & Tan, W. (2020). A novel Coronavirus from patients with pneumonia in China, 2019. New England Journal of Medicine, 382(8), 727–733. https://doi.org/10.1056/nejmoa2001017 First citation in articleCrossrefGoogle Scholar