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Morphometric MRI Analysis

  • Chapter
MRI in Epilepsy

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Morphometric MRI analysis may facilitate the detection and visualization of focal cortical dysplasia and other potentially epileptogenic cortical malformations by highlighting structural alterations such as abnormal gyration, blurring of the gray-white matter junction, and abnormal thickness of the cortical ribbon. In this chapter, a voxel-based implementation of this kind of MRI postprocessing using algorithms of the SPM5 software is presented. The description of methods is accompanied by illustrative examples which show how this approach may aid in the detection of subtle cortical dysplasia, polymicrogyria and gray matter heterotopia, in the delineation of the extent of lesions, and in the differentiation between different types of lesions. Thereby, it increases the diagnostic yield of MRI and appears to be a useful additional tool in the diagnostics and especially presurgical evaluation of epilepsy patients.  

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Authors and Affiliations

  1. Swiss Epilepsy Centre, Zurich, Switzerland

    Hans-Jürgen Huppertz

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  1. Hans-Jürgen Huppertz
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Correspondence to Hans-Jürgen Huppertz .

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  1. , Radiology/Neuroradiology, University Hospital Bonn, Siegmund Freud-Str. 25, Bonn, 53105, Germany

    Horst Urbach

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Huppertz, HJ. (2013). Morphometric MRI Analysis. In: Urbach, H. (eds) MRI in Epilepsy. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_564

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  • DOI: https://doi.org/10.1007/174_2012_564

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-25137-5

  • Online ISBN: 978-3-642-25138-2

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