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Role of Hormones in Common Benign Uterine Lesions: Endometrial Polyps, Leiomyomas, and Adenomyosis

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Hormonal Pathology of the Uterus

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1242))

Abstract

Leiomyoma, adenomyosis, and endometrial polyps are benign uterine disorders which seem to develop in the context of hormonal imbalances, due to steroid hormones, estrogen and progesterone, in association with various factors ranging from genetic factors to modifiable lifestyle factors. A growing body of evidence suggests that those hormones and their receptors are key modulators in the genesis and the growth of those pathologic entities. Further studies are required to understand their involvement in the pathogenesis of those lesions and their link to other factors such as extracellular matrix components, growth factors, chemokines, cytokines, and tissue repair mechanisms.

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Authors and Affiliations

  1. Department of Pathology and Molecular Pathology, Centre Jean Perrin, Clermont-Ferrand, France

    Myriam Kossaï & Frédérique Penault-Llorca

  2. UMR INSERM 1240, Universite Clermont Auvergne, Clermont-Ferrand, France

    Myriam Kossaï & Frédérique Penault-Llorca

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  1. Myriam Kossaï
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  2. Frédérique Penault-Llorca
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Correspondence to Myriam Kossaï or Frédérique Penault-Llorca .

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Editors and Affiliations

  1. Professor Emeritus, Department of Pathology, Department of Obstetrics-Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Liane Deligdisch-Schor

  2. New York Medical College, Westchester Medical Center, Valhalla, NY, USA

    Angelica Mareş Miceli

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Kossaï, M., Penault-Llorca, F. (2020). Role of Hormones in Common Benign Uterine Lesions: Endometrial Polyps, Leiomyomas, and Adenomyosis. In: Deligdisch-Schor, L., Mareş Miceli, A. (eds) Hormonal Pathology of the Uterus . Advances in Experimental Medicine and Biology, vol 1242. Springer, Cham. https://doi.org/10.1007/978-3-030-38474-6_3

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