Abstract
Intraventricular pumps can be used to treat severe pain secondary to cancer or spastic dystonia. First reports of the intraventricular route usage for this purpose involved Ommaya reservoirs with single bolus infusions. After favorable initial results, mechanical pumps were coupled to the reservoir for intermittent boluses. With the advancement of implantable devices, electronic pumps largely replaced the other models. In this chapter we provide insight about details pertinent to the implant technique of those systems.
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References
Obbens EA, Hill CS, Leavens ME, Ruthenbeck SS, Otis F. Intraventricular morphine administration for control of chronic cancer pain. Pain. 1987;28(1):61–8.
Hosobuchi Y, Li CH. The analgesic activity of human beta-endorphin in man (1,2,3). Commun Psychopharmacol. 1978;2(1):33–7.
Goudas LC, Langlade A, Serrie A, Matson W, Milbury P, Thurel C, et al. Acute decreases in cerebrospinal fluid glutathione levels after intracerebroventricular morphine for cancer pain. Anesth Analg. 1999;89(5):1209–15.
Lazorthes YR, Sallerin BA, Verdié JC. Intracerebroventricular administration of morphine for control of irreducible cancer pain. Neurosurgery. 1995;37(3):422–8. discussion 428-429
Raffa RB, Pergolizzi JV. Intracerebroventricular opioids for intractable pain. Br J Clin Pharmacol. 2012;74(1):34–41.
Cramond T, Stuart G. Intraventricular morphine for intractable pain of advanced cancer. J Pain Symptom Manag. 1993;8(7):465–73.
Dennis GC, DeWitty RL. Long-term intraventricular infusion of morphine for intractable pain in cancer of the head and neck. Neurosurgery. 1990;26(3):404–7; discussion 407-408
Leavens ME, Hill CS, Cech DA, Weyland JB, Weston JS. Intrathecal and intraventricular morphine for pain in cancer patients: initial study. J Neurosurg. 1982;56(2):241–5.
Lee TL, Kumar A, Baratham G. Intraventricular morphine for intractable craniofacial pain. Singap Med J. 1990;31(3):273–6.
Lobato RD, Madrid JL, Fatela LV, Rivas JJ, Reig E, Lamas E. Intraventricular morphine for control of pain in terminal cancer patients. J Neurosurg. 1983;59(4):627–33.
Nurchi G. Use of intraventricular and intrathecal morphine in intractable pain associated with cancer. Neurosurgery. 1984;15(6):801–3.
Staquet H, Dupoiron D, Nader E, Menei P. Intracerebroventricular pain treatment with analgesic mixtures including Ziconotide for intractable pain. Pain Physician. 2016;19(6):E905–15.
Karavelis A, Foroglou G, Selviaridis P, Fountzilas G. Intraventricular administration of morphine for control of intractable cancer pain in 90 patients. Neurosurgery. 1996;39(1):57–61. discussion 61-62
Lee DJ, Gurkoff GG, Goodarzi A, Muizelaar JP, Boggan JE, Shahlaie K. Intracerebroventricular opiate infusion for refractory head and facial pain. World J Clin Cases. 2014;2(8):351–6.
Albright AL. Intraventricular baclofen infusion for dystonia. Report of Two Cases. J Neurosurg. 2006;105(1 Suppl):71–4.
Albright AL, Ferson SS. Intraventricular baclofen for dystonia: techniques and outcomes. Clinical article. J Neurosurg Pediatr. 2009;3(1):11–4.
Rocque BG, Leland AA. Intraventricular vs intrathecal baclofen for secondary dystonia: a comparison of complications. Neurosurgery. 2012;70(2 Suppl Operative):321–5. discussion 325-326
Ruggiero C, Meccariello G, Spennato P, Mirone G, Graziano S, Gilone M, et al. Early intraventricular baclofen therapy (IVB) for children with dystonic and dysautonomic storm. Childs Nerv Syst ChNS. 2019;35(1):15–8.
Turner M, Nguyen HS, Cohen-Gadol AA. Intraventricular baclofen as an alternative to intrathecal baclofen for intractable spasticity or dystonia: outcomes and technical considerations. J Neurosurg Pediatr. 2012;10(4):315–9.
Liebman JM, Pastor G. Antinociceptive effects of baclofen and muscimol upon intraventricular administration. Eur J Pharmacol. 1980;61(3):225–30.
Monaco BA, Alho EJL, Okuda FAF. Dystonic-spastic vulvodynia-related treatment with intraventricular baclofen in a cerebral palsy patient. Neuromodulation. 2020;23(3):14536.
Albright AL. Technique for insertion of intraventricular baclofen catheters. J Neurosurg Pediatr. 2011;8(4):394–5.
Wilson TJ, Stetler WR, Al-Holou WN, Sullivan SE. Comparison of the accuracy of ventricular catheter placement using freehand placement, ultrasonic guidance, and stereotactic neuronavigation. J Neurosurg. 2013;119(1):66–70.
Deer TR, Pope JE, Hayek SM, Lamer TJ, Veizi IE, Erdek M, et al. The Polyanalgesic Consensus Conference (PACC): recommendations for intrathecal drug delivery: guidance for improving safety and mitigating risks. Neuromodulation. 2017;20(2):155–76.
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Assumpcao de Monaco, B., Graciolli Cordeiro, J. (2022). Intracerebroventricular Drug Infusion System Implant: Surgical Technique. In: Freitas, T.d.S., Assumpcao de Monaco, B., Golovac, S. (eds) Neuromodulation Techniques for Pain Treatment. Springer, Cham. https://doi.org/10.1007/978-3-030-84778-4_18
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DOI: https://doi.org/10.1007/978-3-030-84778-4_18
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