Summary
Serial determinations of averaged evoked responses (AER) and homovanillic acid (HVA) in cerebrospinal fluid (CSF) were made during the psychotic period and recovery phase in a patient with Addison's disease. The patient was treated with cortisone continuously, 2 series of Uni-ECT without effect in the early case history and neuroleptics (haloperidole), giving complete remission, at the end.
Clinical recovery was accompanied by a 7 fold increase of HVA in CSF, AER-amplitudes increased with about 30% and AER-latencies diminished with about 7%.
Zusammenfassung
Mehrfache Registrierungen der gemittelten, visuellen und somatosensorischen evozierten Hirnpotentiale (AER) und der Homovanillinsäure (HVA) im Liquor cerebrospinalis (CSF) wurden während einer Psychose und nachfolgender Besserung bei einem Patienten mit Addisonscher Krankheit durchgeführt. Der Patient war mit Cortison kontinuierlich und anfangs mit zwei Serien von Elektroschocks ohne Erfolg behandelt. Mit Haioperidol wurde eine vollständige Remission erreicht.
Die klinische Besserung war von einer siebenfachen Erhöhung der HVA im Liquor gefolgt, die AER-Amplituden wurden um 30% größer und AER-Latenzzeiten um 7% verkürzt.
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References
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Supported (in part) by a grant from Leo Pharmaceuticals Ltd.—Psychiat. Res. grant no. 70039 and by the Medical Research Council, grant. no. B21X-2568.
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Mattsson, B., Perris, C. Average evoked responses (AER) and homovanillic acid (HVA) in cerebrospinal fluid (CSF) in a psychotic patient with Addison's disease. Arch. Psychiat. Nervenkr. 219, 351–355 (1974). https://doi.org/10.1007/BF00343605
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DOI: https://doi.org/10.1007/BF00343605
Key words
- Average Evoked Responses (AER)
- Homovanillic Acid (HVA)
- CSF
- Addison's Disease
- Psychosis
- Electroconvulsive Treatment (ETC)