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The clinical effect of felodipine and nifedipine in Raynaud's phenomenon

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Summary

Sixteen patients participated in a double-blind cross-over trial comparing the effect of two dosages of the new calcium entry blocker, felodipine, with nifedipine in the treatment of Raynaud's phenomenon. The effect was evaluated using a symptom recording system. As no difference was found between the 3 treatments, the lower dose of felodipine (10 mg) may be preferable as only one dose per day is necessary.

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Authors and Affiliations

  1. Department of Anesthesiology, Gentofte Hospital, Denmark

    J. F. Schmidt & N. Valentin

  2. Department of Clinical Physiology and Nuclear Medicine, Herlev Hospital, University of Copenhagen, Denmark

    S. Levin Nielsen

Authors
  1. J. F. Schmidt
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  2. N. Valentin
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  3. S. Levin Nielsen
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Schmidt, J.F., Valentin, N. & Levin Nielsen, S. The clinical effect of felodipine and nifedipine in Raynaud's phenomenon. Eur J Clin Pharmacol 37, 191–192 (1989). https://doi.org/10.1007/BF00558230

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  • DOI: https://doi.org/10.1007/BF00558230

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