Summary
Relations among exercise acidosis and various electrolyte concentrations in plasma of femoral venous blood were investigated during bicycling. At equal work rates the changes in endurance trained athletes were compared with the changes in non-athletes. The increase of [Ca++] and [Mg++] could be explained by hemoconcentration. In untrained [H+], [K+], [orthophosphate] (P i ), [lactate] (Lac) and [protein] (Prot) increased significantly more than in trained subjects. Actual [HCO3 −] rose at low work rates, at higher rates it decreased in the untrained while remaining constant in the athletes. [Cl−] did not change during work. Na+ shift into the working muscles must occur. A high correlation does exist between [H+] and [K+], [P i ] and Na+ shift, respectively. This confirms the concept of a strong interaction between the H+ and the Na+−K+ transport. Probably P i follows K+ through the cell membrane. From the ratio of K+ and P i release it might be possible to calculate the intracellular pH. The calculated osmolality (Osm) increased more in untrained than in trained subjects primarily caused by changes in [Lac−] and [HCO3 −].
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Tibes, U., Hemmer, B., Schweigart, U. et al. Exercise acidosis as cause of electrolyte changes in femoral venous blood of trained and untrained man. Pflugers Arch. 347, 145–158 (1974). https://doi.org/10.1007/BF00592396
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DOI: https://doi.org/10.1007/BF00592396