Summary
A patient is presented here who had gastric sarcoidosis which was initially diagnosed as Menetrier's disease. The English medical literature comprises 19 cases with symptomatic gastric sarcoidosis, and these are reviewed. The clinical, roentgenographic, and endoscopic findings in gastric sarcoidosis are quite variable, but of the symptomatic patients, 75% present with pain and 25% with bleeding; surgery is required in 50% of patients, while of those treated with corticosteroids, 66% improve symptomatically. Endoscopic biopsies are accurate and essential in establishing the diagnosis.
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References
Fung WP, Foo KT, Lee YS: Gastric sarcoidosis presenting with hematemesis. Med J Aust 2:47–49, 1975
Gould SR, Handley AJ, Barnardo DE: Rectal and gastric involvement in a case of sarcoidosis. Gut 14:971–973, 1973
Thomas TV, Wiebe KC, Heilbrunn A, Thio RT: Sarcoidosis of the stomach: Long-term follow-up of surgical therapy. Am Surg 38:465–467, 1972
Korsager S: Sarcoidosis of the stomach, a case report. Scand J Respir Dis 60:24–28, 1979
Fulton A, Jampol L, Albert DM: Gastrointestinal sarcoidosis diagnosed by conjunctival biopsy. Am J Ophthalmol 82:102–104, 1976
Konda J, Ruth M, Sassaris M, Hunter FM: Sarcoidosis of the stomach and rectum. Am J Gastroenterol 73:516–518, 1980
Kremer RM, Williams JS: Gastric sarcoidosis: A difficult diagnosis. Am Surg 36:686–690, 1970
Nathan MH, Newman A, Ochsner JL, Blum L: Sarcoidosis of the upper gastrointestinal tract. Am J Roentgenol 84:275–280, 1960
Scott NM, Smith VM, Cox PA, Palmer ED: Sarcoid and sarcoid-like granulomas of the stomach. Arch Intern Med 92:741–749, 1953
Levere RD: Sarcoidosis with gastric involvement. Gastroenterology 42:189–192, 1962
Orie NGM, Van Rijssel TG, Van Der Zwaag GL: Pyloric stenosis in sarcoidosis. Acta Med Scand 138:139–143, 1950
Blackstone MO, Dhar GJ, Mizuno H, Para MF: Gastric sarcoidosis presenting as antral scarring. Gastrointest Endosc 22:211–212, 1976
McLaughlin JS, Van Eck W, Thayer W, Albrink WS, Hayes MA: Gastric sarcoidosis. Ann Surg 153:283–288, 1961
Jolobe OMP, Montgomery RD: Gastric sarcoidosis. Gastrointest Endosc 27:199–200, 1981
Sirak HD: Boeck's sarcoid of the stomach simulating linitus [sic] plastica. Arch Surg 69:769–776, 1954
Pearce J, Ehrlich A: Gastric sarcoidosis. Ann Surg 141:115–119, 1955
Ramirez JJ, Ponka JL, Haubrich WS: Massive hemorrhage from sarcoid ulcers in the stomach. Henry Ford Hospital Med Bull 12:15–21, 1964
Ona FV: Gastric sarcoid: Unusual cause of upper gastrointestinal hemorrhage. Am J Gastroenterol 75:286–288, 1981
Bennington JL, Porus R, Ferguson B, Hannon G: Cytology of gastric sarcoid: Report of a case. Acta Cytol 12:30–36, 1968
Fahimi HD, Deren JJ, Gottlieb LS, Zamcheck N: Isolated granulomatous gastritis: Its relationship to disseminated sarcoidosis and regional enteritis. Gastroenterology 45:161–175, 1963
Palmer ED: Note on silent sarcoidosis of the gastric mucosa. J Lab Clin Med 52:231–234, 1958
Wadina GS, Melamed A: Gastric granuloma (sarcoidosis?). Am J Gastroenterol 45:11–21, 1966
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Chinitz, M.A., Brandt, L.J., Frank, M.S. et al. Symptomatic sarcoidosis of the stomach. Digest Dis Sci 30, 682–688 (1985). https://doi.org/10.1007/BF01308419
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DOI: https://doi.org/10.1007/BF01308419