Abstract
The present study reveals the effect of Musa paradisiaca stem juice on blood glucose level (BGL) of normal & diabetic rats. The dose of 500 mg/kg bodyweight produces a significant rise of 28.3% in blood glucose level after 6h of oral administration in normal rats. Whereas, in sub diabetic rats the same dose produces a rise of 16.4% in blood glucose levels within 1h during glucose tolerance test (GTT) and a rise of 16% after 4 h in fasting blood glucose levels of severe diabetic cases. These results were unexpected and important to report as other species of Musa like Musa sapientum has been reported for its hypoglycemic effect.
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Kesari AN, Gupta R, Watal G. Hypoglycemic effects ofMurraya koenigii on normal and alloxan-diabetic rabbits. J Ethnopharmacol 2005; 97(2): 247–51.
Grover JK, Yadav S, Vats V. Medicinal plants of India with antidiabetic potential. J Ethnopharmacol 2002; 81: 81–100.
Rahman AU, Zaman K. Medicinal Plants with Hypoglycemic activity. J Ethnopharmacol 1989; 26: 1–55.
Ivorra MD, Daya M, Villan A. A review of Natural Products and plants as potential antidiabetic drugs. J Ethnopharmacol 1989; 27: 243–75.
Pellai N, Aashan TN. Ayurveda Prakashika. S.T. Reddiar and Son, Vidyarambham Press, Quilon, 1955, 97 pp.
Kailash, P, Bharathi K, Srinivasan K. Evaluation of Musa (Paradisiaca Linn. Cultivar) “Puttubale” stem juice for antilithiatic activity in albino rats. Ind J Physiol and Pharmacol 1993; 37: 337–41.
Kailash P, Varalakshmi P. Effect of banana stem juice on biochemical change in liver of normal and hyperoxaluric rats. Ind J Exp Biol 1992; 30: 440–2.
Gibson N. Dietary modulation of the human gut micro flora using prebiotics. Britain J Nutrition 1998; 80(4)S: 209–12.
Elliot RC, Heward EJF. The influence of a banana supplemented diet on gastric ulcers in mice. Pharmacol Research Communication 1976; 8: 167–71.
Best R. The antiulcerogenic activity of the unripe plantain banana. Brit J Pharmac 1984; 82: 107–16.
Goel S. Stimulation of gastric and colonic mucosal eicosonoid synthesis by plantain banana. J Pharmceutial and Pharmacol 1989; 41: 747–50.
Lewis G, Shaw H. A natural flavonoid and synthetic analogues protect the gastric mucosa from aspirin-induced erosion. J Nutrition Biochem 2001; 12(2): 95–100.
Jain SR, Sharma SN. Hypoglycemic effect ofMusa Sapientum L. flowers. Planta Medica 1967; 4: 439–42.
Jain SR. Hypoglycemic Principle inMusa Sapientum L. its Isolation. Planta Medica 1968; 5: 43–7.
Pari L, Maheshwari UJ. Hypoglycemic effect ofMusa sapientum L. in alloxan-induced diabetic rats. J Ethnopharmacol 1999; 68: 321–25.
Pari L, Maheshwari UJ. Antihyperglycemic activity ofMusa sapientum flowers: effect on lipid peroxidation in alloxan diabetic rats. Phytotherapy Research 2000; 14: 136–8.
Braham D, Trinder P. Estimation of glucose by glucose oxidase method. Analyst 1972; 97: 142–5.
Brosky G, Logothelopoulos J. Streptozotocin diabetes in the mouse and guinea pig. Diabetes 1969; 18: 606–9.
Dhar ML, Dhar MM, Dhawan BN, Mehrotra BN, Srimal RC, Tandon JS. Screening of Indian plants for biological activity: Part IV. Ind J Exp Biol 1973; 11: 43–55.
Baiely CJ. Biguanides and NIDDM. Diabetes Care 1992; 15: 755–72.
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Singh, S.K., Kesari, A.N., Rai, P.K. et al. Assessment of glycemic potential ofMusa paradisiaca stem juice. Indian J Clin Biochem 22, 48–52 (2007). https://doi.org/10.1007/BF02913313
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DOI: https://doi.org/10.1007/BF02913313